Kris Mendenhall
Novartis
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Publication
Featured researches published by Kris Mendenhall.
Journal of Medicinal Chemistry | 2014
Christopher Mcbride; Barry Levine; Yi Xia; Cornelia Bellamacina; Timothy D. Machajewski; Zhenhai Gao; Paul A. Renhowe; William R. Antonios-Mccrea; Paul A. Barsanti; Kristin Brinner; Abran Costales; Brandon M. Doughan; Xiaodong Lin; Alicia Louie; Maureen Mckenna; Kris Mendenhall; Daniel Poon; Alice Rico; Michael Wang; Teresa E. Williams; Tinya Abrams; Susan Fong; Thomas Hendrickson; Dachuan Lei; Julie Lin; Daniel Menezes; Nancy Pryer; Pietro Taverna; Yongjin Xu; Yasheen Zhou
Utilizing structure-based drug design, a novel dihydropyridopyrimidinone series which exhibited potent Hsp90 inhibition, good pharmacokinetics upon oral administration, and an excellent pharmacokinetic/pharmacodynamic relationship in vivo was developed from a commercial hit. The exploration of this series led to the selection of NVP-HSP990 as a development candidate.
Archive | 2006
Timothy D. Machajewski; Cynthia Shafer; Christopher Mcbride; William R. Antonios-McCrea; Brandon M. Doughan; Barry Haskell Levine; Yi Xia; Maureen Mckenna; X. Michael Wang; Kris Mendenhall; Yasheen Zhou; Baoqing Gong; Dan Gu; John Dolan; John Tulinsky; Kristin Brinner; Zhenhai Gao; Daniel Poon; Paul A. Barsanti; Xiaodong Lin; Abran Costales; Alice Rico; Nathan Brammeier; Teresa E. Pick; Paul A. Renhowe
Archive | 2006
Timothy D. Machajewski; Zhenhai Gao; Barry H. Levine; William R. Antonios-Mccrea; Cornelia Bellamacina; Abran Costales; Brandon M. Doughan; Susan Fong; Thomas Hendrickson; Xiaodong Lin; Christopher Mcbride; Maureen Mckenna; Alice Rico; Cynthia Shafer; X. Michael Wang; Yasheen Zhou; Yi Xia; Kris Mendenhall
Archive | 2005
Weibo Wang; Paul A. Barsanti; Yi Xi; Rustum S. Boyce; Sabina Pecchi; Nathan Brammeier; Megan C. Phillips; Kris Mendenhall; Kelly Wayman; Liana Marie Lagniton; Ryan Constantine; Hong Yang; Elizabeth Mieuli; Savithri Ramurthy; Elisa Jazan; Anu Sharma; Jain Rama; Sharadha Sabramanian; Paul A. Renhowe; Kenneth W. Bair; David Duhl; Annette Walter; Tinya Abrams; Kay Huh; Eric J. Martin; Mark Knapp; Vincent P. Le
Archive | 2009
Weibo Wang; Paul A. Barsanti; Yia Xia; Rustum Boyce; Sabina Pecchi; Nathan Brammeier; Megan C. Phillips; Kris Mendenhall; Kelly Wayman; Liana Marie Lagniton; Ryan Constantine; Hong Yang; Elizabeth Mieuli; Savithri Ramurthy; Elisa Jazan; Anu Sharma; Rama Jain; Sharadha Subramanian; Paul A. Renhowe; Kenneth W. Bair; David Duhl; Annette Walter; Tinya Abrams; Kay Huh; Eric J. Martin; Mark Knapp; Vincent P. Le
Archive | 2006
Paul A. Barsanti; Yi Xia; Weibo Wang; Kris Mendenhall; Liana Marie Lagniton; Savithri Ramurthy; Megan C. Phillips; Sharadha Subramanian; Rustum Boyce; Nathan Brammeier; Ryan Constantine; David Duhl; Annette Walter; Tinya Abrams; Paul A. Renhowe
Archive | 2007
Yi Xia; Kris Mendenhall; Paul A. Barsanti; Annette Walter; David Duhl; Paul A. Renhowe
Archive | 2006
Cornelia Bellamacina; Abran Costales; Brandon M. Doughan; Susan Fong; Zhenhai Gao; Thomas Hendrickson; Barry H. Levine; Xiaodong Lin; Timothy D. Machajewski; Christopher Mcbride; William R. Antonios-Mccrea; Maureen Mckenna; Kris Mendenhall; Alice Rico; Cynthia Shafer; Xiaolun Wang; Yi Xia; Yasheen Zhou
Archive | 2012
Weibo Wang; Paul A. Barsanti; Xia Yia; Rustum Boyce; Sabina Pecchi; Nathan Brammeier; Megan C. Phillips; Kris Mendenhall; Kelly Wayman; Liana Marie Lagnition; Ryan Constantine; Hong Yang; Elizabeth Mieuli; Savithri Ramurthy; Elisa Jazan; Anu Sharma; Rama Jain; Sharadha Subramanian; Paul A. Renhowe; Kenneth W. Bair; David Duhl; Annette Walter; Tinya Abrams; Kay Huh; Eric J. Martin; Mark Knapp; Vincent P. Le
Archive | 2011
Timothy D. Machajewski; Cynthia Shafer; Christopher Mcbride; William R. Antonios-McCrea; Brandon M. Doughan; Barry Haskell Levine; Yi c; Maureen Mckenna; X. Michael Wang; Kris Mendenhall; Yasheen Zhou; Baoqing Gong; Dan Gu; John Dolan; John Tulinsky; Kristin Brinner; Zhenhai Gao; Paul A. c; o Novartis Vaccines; Daniel c; Xiaodong c; Teresa c; Abran c; Nathan c; Alice c
