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Dive into the research topics where Kusum Gupta is active.

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Featured researches published by Kusum Gupta.


Hematology | 2009

Role of platelet volume indices in the differential diagnosis of thrombocytopenia: a simple and inexpensive method

Sangeeta Borkataky; Ritu Jain; Ruchika Gupta; Sompal Singh; Gopal Krishan; Kusum Gupta; Madhur Kudesia

Abstract Thrombocytopenia may result from hypoproliferation in marrow, or peripheral destruction of platelets. Distinction between these two categories is usually made by bone marrow examination. Some studies in literature hint that platelet volume indices are differentially altered in various causes of thrombocytopenia. The present study was aimed at investigating the role of platelet volume indices in the differential diagnosis of thrombocytopenia. Sixty healthy controls and 60 patients (study group) with thrombocytopenia (platelet count < 150 × 109/l) were included in the study. The study group was divided into two categories: hypoproliferative (megaloblastic and non-megaloblastic) and destructive thrombocytopenia. Clinical features, platelet counts and platelet indices were studied in both these categories, and statistical analysis was performed. Platelet counts in the three categories of thrombocytopenia were statistically not different. All the three platelet volume indices were significantly higher in megaloblastic group as compared to the non-megaloblastic hypoproliferative category. Platelet distribution width (PDW) was significantly different between destructive thrombocytopenia and non-megaloblastic hypoproliferative groups. In conclusion, we recommend the division of hypoproliferative category of thrombocytopenia into megaloblastic and non-megaloblastic types. Alterations in platelet indices, especially PDW can differentiate non-megaloblastic hypoproliferative category from both the destructive and megaloblastic thrombocytopenia category. These simple indices can be routinely used in the initial evaluation of a patient with thrombocytopenia.


Diagnostic Cytopathology | 2009

Significance of incidental detection of filariasis on aspiration smears: A case series

Sampada Gupta; Ruchika Gupta; Bhawna Bansal; Sompal Singh; Kusum Gupta; Madhur Kudesia

Filariasis is a major public health problem in tropical and subtropical countries including India. Although there are reports of incidentally diagnosed cases of lymphatic filariasis in the existing literature, the significance of this finding needs to be summarised in one place. The association of filariasis with neoplasms is still debatable.


Diagnostic Cytopathology | 2009

Clear-cell hidradenoma in a child: a diagnostic dilemma for the cytopathologist.

Ruchika Gupta; Sompal Singh; Kusum Gupta; Madhur Kudesia

Primary cutaneous tumors are infrequently subjected to fine needle aspiration cytology. As a result, the cytological reports of skin adnexal tumors like hidradenoma are scarce in the available literature.


Diagnostic Cytopathology | 2009

Nuclear morphometry and texture analysis of B‐cell non‐Hodgkin lymphoma: Utility in subclassification on cytosmears

Shilpa Gupta; Ruchika Gupta; Sompal Singh; Kusum Gupta; Madhur Kudesia

Non‐Hodgkin lymphoma (NHL) is a heterogeneous group of lymphoid neoplasms and accurate subclassification is an essential prerequisite for proper management of patients. This study was aimed at evaluating the utility of nuclear morphometry and textural features on cytology smears to classify the cases of NHL on aspiration cytology.


Cases Journal | 2009

Lichen planus of uterine cervix - the first report of a novel site of occurrence: a case report.

Ruchika Gupta; Bhavna Bansal; Sompal Singh; Indra Yadav; Kusum Gupta; Madhur Kudesia

IntroductionLichen planus is an immune mediated inflammatory lesion involving skin and mucosal sites including oral mucosa, vulva and rarely vagina. Lichen planus occurring at mucosal sites has been shown to be associated with squamous cell carcinoma in a proportion of cases. To the best of our knowledge, no case of lichen planus of uterine cervix has been reported in the available literature.Case PresentationA 45-year-old female underwent vaginal hysterectomy for uterine prolapse. The resected specimen showed a bluish-colored area in the non-dependent part of the ectocervix. Microscopic sections from this area showed dense lymphocytic infiltrate at the junction of mucosa and submucosa causing disruption of the basal cell layer. On immunohistochemical examination there was predominance of CD8+ T lymphocytes at the junction with scattered CD4+ T lymphocytes, characteristic of lichen planus. Based on the history and negative serum antibody titers, other differential diagnoses including lupus erythematosus and drug reaction were excluded. The patient did not have any cutaneous or oral lesions of lichen planus.ConclusionLichen planus of uterine cervix is a hitherto unreported entity, and is worth studying considering the premalignant potential of lichen planus at other mucosal sites.


Indian Journal of Dermatology, Venereology and Leprology | 2008

Primary cutaneous B-cell lymphoblastic lymphoma

Ruchika Gupta; Sangeeta Borkataky; Deepti Aggarwal; Sompal Singh; Kusum Gupta; Madhur Kudesia

652 in dust and air, and this increased exposure can lead to a sensitization against this metal, even in very low doses, with risk of allergic reaction, especially in susceptible individuals. Several authors have described reactions both to nickel and palladium ions,[1-3] which has led to the thinking that the reaction is not dependent on the element itself but rather on the formation of complexes between the ions and skin proteins.


Journal of Medical Case Reports | 2008

Avascular necrosis of humeral head in an elderly patient with tuberculosis: a case report

Renu Agarwal; Ruchika Gupta; Sompal Singh; Kusum Gupta; Madhur Kudesia

IntroductionOsteonecrosis (avascular necrosis) is known to be caused by high-dose corticosteroid therapy, alcoholism and rarely by infections. However, a tubercular etiology of this condition is very rare. A review of the literature yielded only a few cases of polyarticular tuberculosis with osteonecrosis in immunosuppressed individuals. No case of monoarticular tubercular osteonecrosis diagnosed by aspiration cytology was found. Since tuberculosis is a curable disease, an early and accurate diagnosis is essential.Case presentationA 60-year-old Indian man presented with diffuse swelling and pain in the left shoulder for the previous 6 months. A computed tomography scan of the left shoulder revealed crescentic lucency in the humeral head, suggestive of osteonecrosis. Fine needle aspiration cytology smears from the swelling showed features of an acute suppurative lesion. Stain for acid-fast bacillus was positive and thus, a final clinico-pathological diagnosis of osteonecrosis of humeral head with tubercular etiology was rendered. The patient was initiated on anti-tuberculous therapy with symptomatic improvement in his condition.ConclusionOsteonecrosis, a debilitating disease, may rarely occur due to tuberculosis, especially in endemic areas. Fine needle aspiration cytology is an effective and inexpensive modality for an early diagnosis of the tubercular etiology of osteonecrosis.


Pediatric and Developmental Pathology | 2007

Congenital Sialolipoma of Parotid Gland: A Report of Rare and Recently Described Entity with Review of Literature

Bhavna Bansal; Anurag S. Ramavat; Sampada Gupta; Sompal Singh; Amitabh Sharma; Kusum Gupta; Asit Mittal; Madhur Kudesia


Indian Journal of Hematology and Blood Transfusion | 2010

Hemophagocytic Lymphohistiocytosis in B-Cell Lymphoproliferative Disorder: Report of a Rare Association

Deepti Aggarwal; Ruchika Gupta; Sompal Singh; Kusum Gupta; Madhur Kudesia


Proceedings of the Indian National Science Academy | 2015

Modified Surface Tension of a QGP-Droplet Under One Loop Correction in Peshier Potential

S. Somorendro Singh; Agam K. Jha; Kusum Gupta

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Madhur Kudesia

Maulana Azad Medical College

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Sompal Singh

Maulana Azad Medical College

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Ruchika Gupta

Maulana Azad Medical College

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Sampada Gupta

Maulana Azad Medical College

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Deepti Aggarwal

Maulana Azad Medical College

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Sonali Kalra

Maulana Azad Medical College

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