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Dive into the research topics where Kwame McKenzie is active.

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Featured researches published by Kwame McKenzie.


British Journal of Psychiatry | 2002

Social capital and mental health

Kwame McKenzie; Rob Whitley; Scott Weich

Evidence for inequalities in morbidity and mortality by occupational social class and material standard of living has become irrefutable ([Acheson, 1998][1]). Attention has now turned to the effects of social context ([MacIntyre et al , 1993][2]; [MacIntyre, 1997][3]; [Ecob & MacIntyre, 2000][4]; [


BMJ | 2001

Incidence of schizophrenia in ethnic minorities in London: ecological study into interactions with environment

Jane Boydell; J. van Os; Kwame McKenzie; Judith Allardyce; R Goel; R G McCreadie; Robin M. Murray

Abstract Objective: To determine whether the incidence of schizophrenia among people from non-white ethnic minorities is greater in neighbourhoods where they constitute a smaller proportion of the total population. Design: Ecological design including retrospective study of case records to calculate the incidence of schizophrenia in the ethnic minority population across electoral wards and multi-level analysis to examine interaction between individuals and environment. Setting: 15 electoral wards in Camberwell, South London. Participants: All people aged 16 years and over who had contact with psychiatric services during 1988-97. Main outcome measure: Incidence rates of schizophrenia according to Research Diagnostic Criteria. Results: The incidence of schizophrenia in non-white ethnic minorities increased significantly as the proportion of such minorities in the local population fell. The incidence rate ratio varied in a dose-response fashion from 2.38 (95% confidence interval 1.49 to 3.79) in the third of wards where non-white ethnic minorities formed the largest proportion (28-57%) of the local population to 4.4 (2.49 to 7.75) in the third of wards where they formed the smallest proportion (8-22%). Conclusion: The incidence of schizophrenia in non-white ethnic minorities in London is greater when they comprise a smaller proportion of the local population. What is already known on this topic An increased incidence of schizophrenia has been reported in several ethnic minorities in the United Kingdom Biological risk factors do not seem to explain this Reports from the United States have shown an association between the proportion of an ethnic minority living in an area and their admission rates for mental illness in general What this study adds The lower the proportion of non-white ethnic minorities in a local area the higher the incidence of schizophrenia in those minorities


Psychological Medicine | 2007

Parental separation, loss and psychosis in different ethnic groups: a case-control study

Craig Morgan; James B. Kirkbride; Julian Leff; Tom Craig; Gerard Hutchinson; Kwame McKenzie; Kevin Morgan; Paola Dazzan; Gillian A. Doody; Peter B. Jones; Robin M. Murray; Paul Fearon

BACKGROUND Numerous studies have reported high rates of psychosis in the Black Caribbean and Black African populations in the UK. However, few studies have investigated the role of specific risk factors in different ethnic groups. We sought to investigate the relationship between long-term separation from, and death of, a parent before the age of 16 and risk of adult psychosis in different ethnic groups. METHOD All patients with a first episode of psychosis who made contact with psychiatric services in defined catchment areas in London and Nottingham, UK and a series of community controls were included in the AESOP (Aetiology and Ethnicity in Schizophrenia and Other Psychoses) study. Data relating to clinical and social variables, including parental separation and loss, were collected from patients and controls. RESULTS Separation from, and death of, a parent before the age of 16 were both strongly associated with a two- to threefold increased risk of psychosis. The strength of these associations were similar for White British and Black Caribbean (but not Black African) subjects. Separation from (but not death of) a parent was more common among Black Caribbean controls than White British controls. CONCLUSIONS Early separation may have a greater impact in the Black Caribbean population, because it is more common, and may contribute to the excess of psychosis in this population.


American Journal of Public Health | 2005

Racial/Ethnic Discrimination and Common Mental Disorders Among Workers: Findings From the EMPIRIC Study of Ethnic Minority Groups in the United Kingdom?

Kamaldeep Bhui; Stephen Stansfeld; Kwame McKenzie; Saffron Karlsen; James Nazroo; Scott Weich

OBJECTIVES We measured perceived discrimination and its association with common mental disorders among workers in the United Kingdom. METHODS We conducted a secondary analysis of a national sample of 6 ethnic groups (n=2054). Discrimination was measured as reports of insults; unfair treatment at work; or job denial stemming from race, religion, or language. The outcome assessed was presence of common mental disorders. RESULTS The risk of mental disorders was highest among ethnic minority individuals reporting unfair treatment (odds ratio [OR]=2.0; 95% confidence interval [CI]=1.2, 3.2) and racial insults (OR=2.3; 95% CI=1.4, 3.6). The overall greatest risks were observed among Black Caribbeans exposed to unfair treatment at work (OR=2.9; 95% CI=1.2, 7.3) and Indian (OR=3.1; 95% CI=1.4, 7.2), Bangladeshi (OR=32.9; 95% CI=2.5, 436.0), and Irish (OR=2.9; 95% CI=1.1, 7.6) individuals reporting insults. CONCLUSIONS Racial/ethnic discrimination shows strong associations with common mental disorders.


Psychological Medicine | 2005

Racism, psychosis and common mental disorder among ethnic minority groups in England.

Saffron Karlsen; James Nazroo; Kwame McKenzie; Kamaldeep Bhui; Scott Weich

BACKGROUND The aim of this study was to explore the relationship between risk of psychosis, common mental disorder (CMD) and indicators of racism among ethnic minority groups in England and how this relationship may vary by particular ethnic groups. METHOD A multivariate analysis was carried out of quantitative, cross-sectional data from a nationally representative community sample of people aged between 16 and 74 years from the largest ethnic minority groups in England: those of Caribbean, Indian, Pakistani, Bangladeshi and Irish origin. RESULTS Experience of interpersonal racism and perceiving racism in the wider society each have independent effects on the risk of CMD and psychosis, after controlling for the effects of gender, age and socio-economic status. There was some variation in the findings when they were conducted for separate ethnic and gender groups. CONCLUSIONS An understanding of the relationship between racism and mental health may go some way towards explaining the ethnic variations found in both CMD and, particularly, psychosis.


Harvard Review of Psychiatry | 2005

Social capital and psychiatry: Review of the literature

Rob Whitley; Kwame McKenzie

&NA; Social capital is an umbrella term used to describe aspects of social networks, relations, trust, and power, as a function of either the individual or a geographical entity (e.g., a city neighborhood). Increased attention is being paid to the role that social capital can play in determining a variety of physical health outcomes, though less attention has been paid to its role in determining mental health outcomes. This relative inattention continues despite a long historical tradition in psychiatry of exploring the role that socio‐environmental factors can play in the etiology and course of mental illness. In this review, we begin by tracing the historical development of the concept of social capital, describing and analyzing competing definitions. We then proceed to review the published studies that examine the relationship between social capital and mental health—looking first at studies that focus on depression and anxiety, and second at studies that focus on psychoses. After briefly exploring whether social capital can have a detrimental effect on mental health, we discuss how knowledge regarding social capital may aid the clinician and mental health services. We go on to make a number of suggestions relevant to methodological, theoretical, and empirical advancement. These suggestions include refining the definitions of social capital, paying attention to communities without propinquity, and constructing contextual indicators of social capital. We conclude by remarking that social capital may be a promising heuristic for studies in community psychiatry and may even help individual clinicians in designing treatment plans. Despite all this promise, however, there is a lack of strong evidence supporting the hypothesis that social capital protects mental health.


Psychological Medicine | 2014

The association between cannabis use and depression: a systematic review and meta-analysis of longitudinal studies

Shaul Lev-Ran; Michael Roerecke; B. Le Foll; Tony P. George; Kwame McKenzie; Jürgen Rehm

BACKGROUND Longitudinal studies reporting the association between cannabis use and developing depression provide mixed results. The objective of this study was to establish the extent to which different patterns of use of cannabis are associated with the development of depression using meta-analysis of longitudinal studies. METHOD Peer-reviewed publications reporting the risk of developing depression in cannabis users were located using searches of EMBASE, Medline, PsychINFO and ISI Web of Science. Only longitudinal studies that controlled for depression at baseline were included. Data on several study characteristics, including measures of cannabis use, measures of depression and control variables, were extracted. Odds ratios (ORs) were extracted by age and length of follow-up. RESULTS After screening for 4764 articles, 57 articles were selected for full-text review, of which 14 were included in the quantitative analysis (total number of subjects = 76058). The OR for cannabis users developing depression compared with controls was 1.17 [95% confidence interval (CI) 1.05-1.30]. The OR for heavy cannabis users developing depression was 1.62 (95% CI 1.21-2.16), compared with non-users or light users. Meta-regression revealed no significant differences in effect based on age of subjects and marginal difference in effect based on length of follow-up in the individual studies. There was large heterogeneity in the number and type of control variables in the different studies. CONCLUSIONS Cannabis use, and particularly heavy cannabis use, may be associated with an increased risk for developing depressive disorders. There is need for further longitudinal exploration of the association between cannabis use and developing depression, particularly taking into account cumulative exposure to cannabis and potentially significant confounding factors.


Psychological Medicine | 2008

Testing the association between the incidence of schizophrenia and social capital in an urban area

James B. Kirkbride; Jane Boydell; George B. Ploubidis; Craig Morgan; Paola Dazzan; Kwame McKenzie; Robin M. Murray; Peter B. Jones

BACKGROUND Social capital has been considered aetiologically important in schizophrenia but the empirical evidence to support this hypothesis is absent. We tested whether social capital, measured at the neighbourhood level, was associated with the incidence of schizophrenia (ICD-10 F20). MethodWe administered a cross-sectional questionnaire on social capital to 5% of the adult population in 33 neighbourhoods (wards) in South London (n=16 459). The questionnaire contained items relating to two social capital constructs: social cohesion and trust (SC&T) and social disorganization (SocD). Schizophrenia incidence rates, estimated using data from the Aetiology and Ethnicity in Schizophrenia and Other Psychoses (AESOP) study, provided the outcome. We used multi-level Poisson regression to test our hypothesis while controlling for individual- and neighbourhood-level characteristics. RESULTS We identified 148 cases during 565 576 person-years at-risk. Twenty-six per cent of the variation in incidence rates was attributable to neighbourhood-level characteristics. Response from the social capital survey was 25.7%. The association between SC&T and schizophrenia was U-shaped. Compared with neighbourhoods with medial levels of SC&T, incidence rates were significantly higher in neighbourhoods with low [incidence rates ratio (IRR) 2.0, 95% confidence interval (CI) 1.2-3.3] and high (IRR 2.5, 95% CI 1.3-4.8) levels of SC&T, independent of age, sex, ethnicity, ethnic density, ethnic fragmentation and socio-economic deprivation. ConclusionNeighbourhood variation in SC&T was non-linearly associated with the incidence of schizophrenia within an urban area. Neighbourhoods with low SC&T may fail to mediate social stress whereas high SC&T neighbourhoods may have greater informal social control or may increase the risk of schizophrenia for residents excluded from accessing available social capital.


BMC Public Health | 2007

Rates, risk factors & methods of self harm among minority ethnic groups in the UK: a systematic review

Kamaldeep Bhui; Kwame McKenzie; Farhat Rasul

BackgroundStudies suggest that the rates of self harm vary by ethnic group, but the evidence for variation in risk factors has not been synthesised to inform preventive initiatives.MethodsWe undertook a systematic literature review of research about self harm that compared at least two ethnic groups in the United Kingdom.Results25 publications from 1765 titles and abstracts met our inclusion criteria. There was higher rate of self harm among South Asian women, compared with South Asian men and White women. In a pooled estimate from two studies, compared to their white counterparts, Asian women were more likely to self harm (Relative Risk 1.4, 95%CI: 1.1 to 1.8, p = 0.005), and Asian men were less likely to self harm (RR 0.5, 95% CI: 0.4 to 0.7, p < 0.001). Some studies concluded that South Asian adults self-harm impulsively in response to life events rather than in association with a psychiatric illness. Studies of adolescents showed similar methods of self harm and interpersonal disputes with parents and friends across ethnic groups. There were few studies of people of Caribbean, African and other minority ethnic groups, few studies took a population based and prospective design and few investigated self harm among prisoners, asylum seekers and refugees.ConclusionThis review finds some ethnic differences in the nature and presentation of self harm. This argues for ethnic specific preventive actions. However, the literature does not comprehensively cover the UKs diverse ethnic groups.


BMJ | 2007

Institutional racism in mental health care.

Kwame McKenzie; Kamaldeep Bhui

Services have some way to go before they meet the challenges of a multicultural society

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Kamaldeep Bhui

Queen Mary University of London

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Kelly K. Anderson

University of Western Ontario

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Andrew Tuck

Centre for Addiction and Mental Health

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J. van Os

University of Cambridge

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Nina Flora

Centre for Addiction and Mental Health

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