Kyoichi Mizuno
Harvard University
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Featured researches published by Kyoichi Mizuno.
Jacc-cardiovascular Interventions | 2012
Koji Kato; Taishi Yonetsu; Soo-Joong Kim; Lei Xing; Hang Lee; Iris McNulty; Robert W. Yeh; Rahul Sakhuja; Shaosong Zhang; Shiro Uemura; Kyoichi Mizuno; Ik-Kyung Jang
OBJECTIVESnThe aim of the present study was to compare the characteristics of nonculprit coronary plaques between diabetes mellitus (DM) and non-DM patients using 3-vessel optical coherence tomography (OCT) imaging.nnnBACKGROUNDnDM patients have a higher recurrent cardiovascular event rate.nnnMETHODSnPatients who had undergone 3-vessel OCT imaging were identified from the Massachusetts General Hospital OCT Registry. Characteristics of nonculprit plaques were compared between DM and non-DM patients.nnnRESULTSnA total of 230 nonculprit plaques were identified in 98 patients. Compared with non-DM patients, DM patients had a larger lipid index (LI) (averaged lipid arc × lipid length; 778.6 ± 596.1 vs. 1358.3 ± 939.2, p < 0.001) and higher prevalence of calcification (48.4% vs. 72.2%, p = 0.034) and thrombus (0% vs. 8.3%, p = 0.047). DM patients were divided into 2 groups based on glycated hemoglobin (A(1C)) levels of ≤7.9% and ≥8.0%. LI was significantly correlated with diabetic status (778.6 ± 596.1 [non-DM] vs. 1,171.5 ± 708.1 [A(1C) ≤7.9%] vs. 1,638.5 ± 1,173.8 [A(1C) ≥8%], p value for linear trend = 0.005), and fibrous cap thickness was inversely correlated with the A(1C) level (99.4 ± 46.7 μm [non-DM] vs. 91.7 ± 29.6 μm [A(1C) ≤7.9%] vs. 72.9 ± 22.7 μm [A(1C) ≥8%], p value for linear trend = 0.014). Patients with A(1C) ≥8% also had the highest prevalence of thin-cap fibroatheroma (TCFA) and macrophage infiltration.nnnCONCLUSIONSnCompared with non-DM patients, DM patients have a larger LI and a higher prevalence of calcification and thrombus. The LI was larger and TCFA and macrophage infiltration were frequent in patients with A(1C) ≥8%.
Angioscopy | 2016
Hidenori Komiyama; Masamichi Takano; Tomofumi Sawatani; Yusaku Shibata; Masato Matsushita; Osamu Kurihara; Katsuhito Kato; Ryo Munakata; Daisuke Murakami; Noritake Hata; Yoshihiko Seino; Kyoichi Mizuno; Wataru Shimizu
Angioscopy | 2018
Osamu Kurihara; Masamichi Takano; Yasushi Miyauchi; Yoshihiko Seino; Kyoichi Mizuno; Wataru Shimizu
Angioscopy | 2018
Takafumi Ueno; Kyoichi Mizuno; Masami Nishino; Hitoshi Takano; Tadateru Takayama; Yasunori Ueda; Toshiro Shinke; Shuntaro Ikeda; Masaki Awata; Takayuki Ishihara; Shigeru Saito; Masato Nakamura; Kenji Abe; Shinsuke Nanto
Angioscopy | 2017
Kyoichi Mizuno; Masamichi Takano
Angioscopy | 2016
Osamu Kurihara; Masamichi Takano; Kyoichi Mizuno; Yusaku Shibata; Masato Matsushita; Hidenori Komiyama; Katsuhito Kato; Ryo Munakata; Daisuke Murakami; Kentaro Okamatsu; Yasushi Miyauchi; Noritake Hata; Yoshihiko Seino; Wataru Shimizu
Journal of the American College of Cardiology | 2015
Tsunenari Soeda; Seung-Jung Park; Yangsoo Jang; Stephen Lee; Kyoichi Mizuno; Tomonori Itoh; Jack Tan Wei Chieh; Hang Lee; Haibo Jia; Bo Yu; Shiro Uemura; Yoshihiko Saito; Ik-Kyung Jang
Angioscopy | 2015
Tetsuro Shimura; Masamichi Takano; Yoshihiko Seino; Wataru Shimizu; Kyoichi Mizuno
Angioscopy | 2015
Ryo Munakata; Masamichi Takano; Tomohito Hada; Tetsuro Shimura; Osamu Kurihara; Nakahisa Kimata; Toru Inami; Daisuke Murakami; Takayoshi Ohba; Yoshihiko Seino; Wataru Shimizu; Kyoichi Mizuno
Archive | 2013
Asuka Yoshida; Hitoshi Takano; Kuniya Asai; Masahiro Yasutake; Yasuo Amano; Shin-ichiro Kumita; Wataru Shimizu; Kyoichi Mizuno