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Dive into the research topics where Kyoichi Mizuno is active.

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Featured researches published by Kyoichi Mizuno.


Jacc-cardiovascular Interventions | 2012

Comparison of nonculprit coronary plaque characteristics between patients with and without diabetes: a 3-vessel optical coherence tomography study.

Koji Kato; Taishi Yonetsu; Soo-Joong Kim; Lei Xing; Hang Lee; Iris McNulty; Robert W. Yeh; Rahul Sakhuja; Shaosong Zhang; Shiro Uemura; Kyoichi Mizuno; Ik-Kyung Jang

OBJECTIVESnThe aim of the present study was to compare the characteristics of nonculprit coronary plaques between diabetes mellitus (DM) and non-DM patients using 3-vessel optical coherence tomography (OCT) imaging.nnnBACKGROUNDnDM patients have a higher recurrent cardiovascular event rate.nnnMETHODSnPatients who had undergone 3-vessel OCT imaging were identified from the Massachusetts General Hospital OCT Registry. Characteristics of nonculprit plaques were compared between DM and non-DM patients.nnnRESULTSnA total of 230 nonculprit plaques were identified in 98 patients. Compared with non-DM patients, DM patients had a larger lipid index (LI) (averaged lipid arc × lipid length; 778.6 ± 596.1 vs. 1358.3 ± 939.2, p < 0.001) and higher prevalence of calcification (48.4% vs. 72.2%, p = 0.034) and thrombus (0% vs. 8.3%, p = 0.047). DM patients were divided into 2 groups based on glycated hemoglobin (A(1C)) levels of ≤7.9% and ≥8.0%. LI was significantly correlated with diabetic status (778.6 ± 596.1 [non-DM] vs. 1,171.5 ± 708.1 [A(1C) ≤7.9%] vs. 1,638.5 ± 1,173.8 [A(1C) ≥8%], p value for linear trend = 0.005), and fibrous cap thickness was inversely correlated with the A(1C) level (99.4 ± 46.7 μm [non-DM] vs. 91.7 ± 29.6 μm [A(1C) ≤7.9%] vs. 72.9 ± 22.7 μm [A(1C) ≥8%], p value for linear trend = 0.014). Patients with A(1C) ≥8% also had the highest prevalence of thin-cap fibroatheroma (TCFA) and macrophage infiltration.nnnCONCLUSIONSnCompared with non-DM patients, DM patients have a larger LI and a higher prevalence of calcification and thrombus. The LI was larger and TCFA and macrophage infiltration were frequent in patients with A(1C) ≥8%.


Angioscopy | 2016

Very Late In-stent Restenosis due to Neoatherosclerosis in the Second-generation Everolimus-eluting Stent

Hidenori Komiyama; Masamichi Takano; Tomofumi Sawatani; Yusaku Shibata; Masato Matsushita; Osamu Kurihara; Katsuhito Kato; Ryo Munakata; Daisuke Murakami; Noritake Hata; Yoshihiko Seino; Kyoichi Mizuno; Wataru Shimizu


Angioscopy | 2018

Glucose Metabolism Disorder and Angioscopic Findings of Coronary Plaques

Osamu Kurihara; Masamichi Takano; Yasushi Miyauchi; Yoshihiko Seino; Kyoichi Mizuno; Wataru Shimizu


Angioscopy | 2018

Stent Thrombosis and Intrastent Thrombus Formation in Patients Undergoing Elective PCI: Results of an Angioscopic Substudy of the Randomized Trial PRASFIT-Elective (PRASugrel for Japanese PatIenTs with Coronary Artery Disease Undergoing Elective PCI)

Takafumi Ueno; Kyoichi Mizuno; Masami Nishino; Hitoshi Takano; Tadateru Takayama; Yasunori Ueda; Toshiro Shinke; Shuntaro Ikeda; Masaki Awata; Takayuki Ishihara; Shigeru Saito; Masato Nakamura; Kenji Abe; Shinsuke Nanto


Angioscopy | 2017

What Does the Yellow Color of Angioscopy Mean? Why Yellow Plaque Is Always Vulnerable?

Kyoichi Mizuno; Masamichi Takano


Angioscopy | 2016

Relationship between Body Mass Index and Coronary Atherosclerosis Analyzed by Multivessel Angioscopic Study

Osamu Kurihara; Masamichi Takano; Kyoichi Mizuno; Yusaku Shibata; Masato Matsushita; Hidenori Komiyama; Katsuhito Kato; Ryo Munakata; Daisuke Murakami; Kentaro Okamatsu; Yasushi Miyauchi; Noritake Hata; Yoshihiko Seino; Wataru Shimizu


Journal of the American College of Cardiology | 2015

INCIDENCE AND PREDICTORS OF STENT EDGE MEDIAL DISRUPTION: AN IN VIVO OPTICAL COHERENCE TOMOGRAPHY STUDY

Tsunenari Soeda; Seung-Jung Park; Yangsoo Jang; Stephen Lee; Kyoichi Mizuno; Tomonori Itoh; Jack Tan Wei Chieh; Hang Lee; Haibo Jia; Bo Yu; Shiro Uemura; Yoshihiko Saito; Ik-Kyung Jang


Angioscopy | 2015

Angioscopic Comparison of Six-month Arterial Healing between Bare-metal and Drug-eluting Stents in Superficial Femoral Arteries

Tetsuro Shimura; Masamichi Takano; Yoshihiko Seino; Wataru Shimizu; Kyoichi Mizuno


Angioscopy | 2015

Angioscopic Observation of Acute Femoral Artery Occlusion Complicated by Use of Angio-seal Vascular Closure Device

Ryo Munakata; Masamichi Takano; Tomohito Hada; Tetsuro Shimura; Osamu Kurihara; Nakahisa Kimata; Toru Inami; Daisuke Murakami; Takayoshi Ohba; Yoshihiko Seino; Wataru Shimizu; Kyoichi Mizuno


Archive | 2013

Clinical Investigations Comparison of Perfusion-Metabolism Mismatch in 99m Tc-MIBI and 123 I-BMIPP Scintigraphy With Cardiac Magnetic Resonance in Patients With Dilated Cardiomyopathy

Asuka Yoshida; Hitoshi Takano; Kuniya Asai; Masahiro Yasutake; Yasuo Amano; Shin-ichiro Kumita; Wataru Shimizu; Kyoichi Mizuno

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Bo Yu

Harvard University

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