Kyosuke Yokota
Toho University
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Acta neurochirurgica | 2013
Mitsuru Honda; Shigeru Sase; Kyosuke Yokota; Ryo Ichibayashi; Katsunori Yoshihara; Hiroyuki Masuda; Hiroyuki Uekusa; Jun Nomoto; Nobuo Sugo; Taichi Kishi; Yoshikatsu Seiki
INTRODUCTION Traumatic brain injury (TBI) is widely known to cause dynamic changes in cerebral blood flow (CBF). In particular, secondary brain insults have been reported to decrease CBF. The purpose of this study was to clarify the cerebral circulation in different types of TBI. METHODS Sixty-nine patients with TBI were divided into four groups, the subdural hematoma group, the contusion/intracerebral hematoma group, the diffuse axonal injury group, and the diffuse brain swelling group. In these patients, we simultaneously performed Xe-CT and perfusion CT to evaluate the cerebral circulation on post-injury days 1-3. We measured CBF using Xe-CT and mean transit time using perfusion CT and calculated the cerebral blood volume using the AZ-7000 W98 computer system. RESULTS There were no significant differences in the Glasgow Coma Scale score on arrival or the Glasgow Outcome Scale score between the groups. The patients who had suffered focal TBI displayed more significant cerebral circulation disturbances than those that had suffered diffuse TBI. We were able to evaluate the cerebral circulation of TBI patients using these parameters. CONCLUSION Moderate hypothermia therapy, which decreases CBF, the cerebral metabolic rate oxygen consumption (CMRO2), and intracranial pressure might be effective against the types of TBI accompanied by cerebral circulation disturbance. We have to use all possible measures including hypothermia therapy to treat severe TBI patients according to the type of TBI that they have suffered.
Asian journal of neurosurgery | 2012
Mitsuru Honda; Kyosuke Yokota; Ryo Ichibayashi; Katsunori Yoshihara; Hiroyuki Masuda; Hiroyuki Uekusa; Yoshikatsu Seiki; Jun Nomoto; Takeki Nagao; Taichi Kishi; Shigeru Sase
Aims: Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determine the systemic circulation disturbance during the initiation of therapeutic hypothermia by using this continuous neurointensive monitoring system. Materials and Methods: Ten severe brain damage patients treated with hypothermia were enrolled. All patients had Glasgow Coma Scale (GCS) less than or equal to 8, on admission. Results: We verified that heart rate, cardiac output, and oxygen delivery index (DO2I) decreased with decreasing core temperature. We recognized that depressed cardiac index (CI) was attributed to bradycardia, dehydration, and increased systemic vascular resistance index (SVRI) upon initiation of hypothermia. Conclusion: Although the hypothermia has a therapeutic role in severe brain damage patients, we have to carry out this therapy while maintaining their cardiac output using multimodality monitoring devices during hypothermia period.
Neurologia Medico-chirurgica | 2012
Mitsuru Honda; Shigeru Sase; Kyosuke Yokota; Ryo Ichibayashi; Katsunori Yoshihara; Yoshihito Sakata; Hiroyuki Masuda; Hiroyuki Uekusa; Yoshikatsu Seiki; Taichi Kishi
Neurologia Medico-chirurgica | 2007
Jun Nomoto; Yoshikatsu Seiki; Masaaki Nemoto; Hiroshi Takahashi; Hiroshi Terashima; Kyosuke Yokota; Kosuke Kondo; Toshiyuki Kano; Syozo Goto; Nobuo Sugo
Neurologia Medico-chirurgica | 2007
Yoshinori Aoki; Masaaki Nemoto; Kyosuke Yokota; Toshiyuki Kano; Shouzou Goto; Nobuo Sugo
日本シミュレーション外科学会会誌 = Journal of the Japan Society for Simulation Surgery | 2009
Naoyuki Harada; Toshiyuki Kano; Masaaki Nemoto; Kyosuke Yokota; Shozo Goto; Nobuo Sugo
日本シミュレーション外科学会会誌 = Journal of the Japan Society for Simulation Surgery | 2009
Kyosuke Yokota; Naoyuki Harada; Masaaki Nemoto; Toshiyuki Kano; Syozo Goto; Nobuo Sugo
日本シミュレーション外科学会会誌 = Journal of the Japan Society for Simulation Surgery | 2008
Yoshinori Aoki; Naoyuki Harada; Kyosuke Yokota; Masaaki Nemoto; Kosuke Kondo; Toshiyuki Kano; Yoshikatsu Seiki; Nobuo Sugo
日本シミュレーション外科学会会誌 = Journal of the Japan Society for Simulation Surgery | 2008
Hiroyuki Masuda; Kosuke Kondo; Kyosuke Yokota; Masaaki Nemoto; Toshiyuki Kano; Syozo Goto; Yoshikatsu Seiki; Nobuo Sugo
日本シミュレーション外科学会会誌 = Journal of the Japan Society for Simulation Surgery | 2008
Nobuo Sugo; Kosuke Kondo; Kyosuke Yokota; Masaaki Nemoto; Daisuke Haga; Yoshitaka Noguchi; Hiroyuki Masuda; Toshiyuki Kano; Syozo Goto; Yoshikatsu Seiki