Kyung Eun Jung

Medallion-Like Dermal Dendrocyte Hamartoma: Differential Diagnosis with Congenital Atrophic Dermatofibrosarcoma Protuberans

382 Ann Dermatol Received October 9, 2012, Accepted for publication October 18, 2012 Corresponding author: Young Min Park, Department of Dermatology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. Tel: 82-2-2258-6223, Fax: 82-2-599-9950, E-mail: yymmpark6301@hotmail.com This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Dermatol 1994;11:241-245. 6. Elder DE. Dysplastic naevi: an update. Histopathology 2010; 56:112-120. 7. Misago N, Takahashi M, Kohda H. Unilateral dysplastic nevi associated with malignant melanoma. J Dermatol 1991;18: 649-653. 8. Sterry W, Christophers E. Quadrant distribution of dysplastic nevus syndrome. Arch Dermatol 1988;124:926-929. 9. Marghoob AA, Blum R, Nossa R, Busam KJ, Sachs D, Halpern A. Agminated atypical (dysplastic) nevi: case report and review of the literature. Arch Dermatol 2001;137:917-920. 10. Bragg JW, Swindle L, Halpern AC, Marghoob AA. Agminated acquired melanocytic nevi of the common and dysplastic type. J Am Acad Dermatol 2005;52:67-73.

A split-face comparison of ablative fractional lasers (CO(2) and Er:YAG) in Asian patients; postprocedure erythema, pain and patient's satisfaction.

Abstract Fractional photothermolysis has become popular in the recent years and is currently widely used for the treatment of scars and for photo-rejuvenation purposes. The fractional photothermolysis is to thermally alter a ‘fraction’ of the skin, leaving intervening areas of normal skin untouched, which rapidly repopulate the altered columns of tissue. Fractional photothermolysis is subdivided into non-ablative and ablative fractional resurfacing. Ablative fractional resurfacing uses fractional CO2 or Er:YAG lasers to create deeper columns of thermal damage.Few studies have compared fractional CO2 and Er:YAG lasers on scars and cutaneous photodamages by a split trial. In this pilot study, we have compared the effects, down time, postprocedure erythema, pain of CO2 and Er:YAG fractional lasers using analysis of clinical photographs, dermoscopic findings and patients rate of satisfaction.

Comparison of modified Korean cupping method and conventional respiratory suction unit for epidermal graft

of authors, we would like to object to the statement that nodular prurigo commonly responds to dapsone. In our hands, dapsone is virtually ineffective in the treatment of prurigo nodularis. Usually, long-term treatment and a combination of different treatment modalities are needed to cure these patients. To summarize, Bonciolini et al. base their correspondence on a large body of personal experience and literature, and their arguments are highly valuable and consistent. Nevertheless, our central idea that dermatitis herpetiformis should be excluded in patients with nodular prurigo is still valid.

Langerhans cell sarcoma: a case report and review of the literature

multiple tumors developed all over the body. We started multiple drug chemotherapy; one course of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone) followed by ESHAP (etoposide, carboplatin, cytarabine, and methylprednisolone). The skin lesions initially responded to treatment. New skin lesions, however, continued to develop between cycles. We repeatedly performed focal radiation therapy against skin tumors. The clinical presentation of PCGD-TCL is variable. Most cases clinically show panniculitis-like ulcerated plaques or patches resembling MF. To our knowledge, there has been no reported case with PCGD-TCL following MF. In most cases of PCGD-TCL, tumor cells are CD4 and CD8. CD4 and CD8 phenotype, however, is not specific to PCGD-TCL. In some MF cases, tumor cells are CD4 and CD8, most of which are of the ab phenotype rather than cd phenotype. Therefore, skin biopsy and immunostaining for TCR-d1 using frozen samples are necessary to distinguish between transformed MF and PCGD-TCL. In summary, we present a unique case of PCGD-TCL following MF. Skin biopsies and immunostaining for TCR-d1 is important to distinguish between these two diseases. To know the true characters of tumor cells will be more important in the era of monoclonal antibody therapies targeting surface molecules of tumor cells.

A Clinical Study of Cutaneous Adverse Reactions to Nonionic Contrast Media in Korea

Background The use of intravenous contrast media (CM) has increased for the diagnosis of several diseases. The newly developed low osmolar nonionic contrast agents cause significantly decreased adverse reactions than the higher osmolar ones. However, adverse reactions may still occur, ranging in severity from minor side effects to severe complications. However, there have been few reports about cutaneous adverse reactions (CARs) to nonionic monomer CM. Objective The purpose of this study was to evaluate clinical features of CAR to intravenous nonionic monomer CM. Methods A total 47,338 examinees underwent intravenous iodinated contrast-enhanced computed tomography scan using nonionic monomer CM. Among the adverse reactions to the CM, we divided them into cutaneous or noncutaneous and immediate (<1 hr) or late (≥1 hr) adverse reactions. Results Adverse reactions were noted in 62 cases out of the total 47,338 cases; 50 cases (80.7%) were categorized CARs. Among them, there were 24 male and 26 female patients. There was no significant difference between the sexes, and CARs occurred in all age groups. The highest occurrence was in the age range of 50~59 years. CARs included urticaria (78%), angioedema (10%), maculopapular rash (8%), erythema (2%), and pruritus without rash (2%). Immediate reactions were 92% (46 cases), while late reactions were 8% (4 cases). Conclusion CARs to nonionic monomer CM accounted for most of the adverse reactions (80.7%) and urticaria was the most common.

Zosteriform transient acantholytic dermatosis

Dear Editor, Transient acantholytic dermatosis (TAD, Grover’s disease) is an acquired pruritic papulovesicular eruption. Unilateral involvement along Blaschko’s line is rare, and only one case with a zosteriform distribution has been reported in the published work. Herein, we report on the second case of TAD with an unusual zosteriform distribution. A 51-year-old man presented with a 3-month history of pruritic, multiple, erythematous to brownish papules with crust on the right waistband area (Fig. 1). As time went on, the original lesions crusted and new lesions developed. The patient complained of pruritus, but denied pain or any other symptoms. The lesions were arranged in a zosteriform pattern along the right T12 dermatome. Over time, the color of the skin lesions became darker. The patient’s medical history included hepatitis B and diabetes mellitus, which were being treated with lamivudine and metformin in the typical amounts. The patient’s past history and family history were unremarkable for a similar skin disease. There was no evidence of internal malignancy based on various examinations. A skin biopsy specimen was taken from the center of the representative lesion. Histological examination demonstrated acantholysis, dyskeratotic cells and suprabasal clefts. The epidermis was characterized by basket weave patterned hyperkeratosis, papillomatosis and exocytosis. The upper dermis showed a moderate perivascular lymphohistiocytic infiltration admixed with some eosinophils (Fig. 2). Based on these clinical and histopathological findings, the diagnosis of TAD was made. The patient was treated with topical (a)