Kyung-Sook Hwang

Estimation of the costs of smoking-related oral disease: a representative South Korean study

OBJECTIVES The objectives of this study were to estimate the socioeconomic and psychological costs associated with smoking-related oral disease (SROD) with the aim of generating objective data that could be used in smoking cessation counselling by dental care providers and could also serve as data with which to set standards and criteria for use in dental health insurance. METHODS Patients were sourced from the 11 dental hospitals associated with dental schools in South Korea. A total of 1,288 of 10,080 patients with SROD were selected to participate in the study for a period of 2 years from January 2009 to March 2011. Data collected were analysed using spss Version 17.0. RESULTS Among the SRODs, the most common was periodontal disease (40.7%). Periodontal disease accounted for the highest social and economic costs. Mouth cancer accounted for the highest psychological cost. CONCLUSIONS In order to reduce associated socioeconomic and psychological costs, dental care providers and government should provide more proactive and more efficient smoking cessation programmes.

ANALYSIS AND INVESTIGATION OF CHEMICAL STABILITY ON PHENOLIC COMPOUNDS IN ZANTHOXYLUM SCHINIFOLIUM-CONTAINING DENTIFRICES

Chromatographic properties and chemical stability of 12 kinds of phenolic compounds Z. schinifolium were investigated and analyzed to use as an antioxidant substance in dentifrices. Twelve compounds were completely separated under 0.01% phosphoric acid-acetonitrile gradient condition at 20°C and detected by photodiode array detector. Each compound showed good linearity at optimized wavelength, and showed good precision and accuracy in dentifrices. Using this analytical method, phenolic compounds in Z. schinifolium fraction and dentifrices were successfully determined. Caffeic acid, quercetin, and xanthoxylin decomposed in aqueous solution, and other compounds were preserved over 94%. It was better to store phenolic compounds under weak acidic conditions (<pH 6) to prevent the decomposition of phenolic compounds. Mixed in dentifrices, about half of the total compounds remained for 45 d, but the preservation rate (%) showed big differences between each compound. Each fraction of Z. schinifolium -containing dentifrice was manufactured and analyzed. In Z. schinifolium dentifrices, 44% of phenolic compounds remained after 2 mo.