L. L. Huckstep | Researchain

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Journal of The Chemical Society, Chemical Communications | 1974

Retention of valine methyl hydrogens in penicillin biosynthesis

D. John Aberhart; John Yeou-Ruoh Chu; Norbert Neuss; Claude H. Nash; John L. Occolowitz; L. L. Huckstep; Nancy De La Higuera

[Me2-2H6]-D,L-valine has been synthesized and incorporated into penicillin V. The mass spectrum of the penicillin V methyl ester showed the retention of all six deuterons in the biosynthetic product.

Tetrahedron Letters | 1968

Aranotin and related metabolites. II. Isolation, characterization, and structures of two new metabolites

Norbert Neuss; R. Nagarajan; B.B. Molloy; L. L. Huckstep

Helvetica Chimica Acta | 1970

Structure of Hygromycin B, an antibiotic from Streptomyces hygroscopicus: the use of CMR. spectra in structure determination, I.

Norbert Neuss; K. F. Koch; B.B. Molloy; W. Day; L. L. Huckstep; Douglas E. Dorman; John D. Roberts

Journal of the American Chemical Society | 1973

Use of chiral isopropyl groups in biosynthesis. Synthesis of (2RS,3S)-[413C]-valine

J. E. Baldwin; J. Loeliger; W. Rastetter; Norbert Neuss; L. L. Huckstep; N. De la Higuera

The Journal of Antibiotics | 1982

High performance liquid chromatography (HPLC) of natural products. V. The use of HPLC in the cell-free biosynthetic conversion of .ALPHA.-aminoadipyl-cysteinyl-valine (LLD) into isopenicillin N.

Norbert Neuss; Donnis M. Berry; J. Kupka; Arnold L. Demain; S. W. Queener; Dale C. Duckworth; L. L. Huckstep

The Journal of Antibiotics | 1981

High performance liquid chromatography (HPLC) of natural products. IV. The use of HPLC in biosynthetic studies of cephalosporin C in the cell-free system.

Roger D. Miller; L. L. Huckstep; McDermott Jp; Queener Sw; S. Kukolja; Douglas O. Spry; Elzey Tk; Lawrence Sm; Norbert Neuss

Helvetica Chimica Acta | 1980

High Performance Liquid Chromatography (HPLC.) of Natural Products. III [1]. Isolation of New Tripeptides from the Fermentation Broth of P. Chrysogenum

Norbert Neuss; Roger D. Miller; C. A. Affolder; Walter Mitsuo Nakatsukasa; J. Mabe; L. L. Huckstep; N. La De Higuera; A. H. Hunt; John L. Occolowitz; J. H. Gilliam

Tetrahedron Letters | 1968