L M Santiago
Oswaldo Cruz Foundation
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Arquivos Brasileiros De Endocrinologia E Metabologia | 2012
Patrícia Echenique Mattos; Laércio Lima Luz; L M Santiago; Inês Echenique Mattos
OBJECTIVE To analyze mortality patterns of patients with diabetes in Brazilian capitals from 1980 to 2007. MATERIALS AND METHODS Age-standardized quadrennial and annual mortality rates were calculated with the world population as reference. Linear regression models were estimated to analyze mortality trends in each capital. RESULTS In the first quadrennial period, the highest rate was 42.89/100,000 in Aracaju; and in the last quadrennial period, 54.38/100,000 in São Luis. Although mortality rates showed statistically significant incremental trends in most capitals, there were regional differences. Belo Horizonte was the only capital to show a declining trend. CONCLUSIONS Part of the observed increment could be attributed to improvements in access to diagnosis and death certification, but regional differences in the prevalence of diabetes risk and protective factors might also be implicated. The absence of a time series of incident cases makes it difficult to determine if these results reflect current trends in the incidence of diabetes in Brazil.
Archives of Gerontology and Geriatrics | 2010
L M Santiago; Cristiane de Oliveira Novaes; Inês Echenique Mattos
The objective was to examine the role of SRH as a predictor of mortality in elderly men in a medium-size Brazilian city. In 2 years of follow-up, 120 deaths occurred in the study population, with the following main causes: cardiovascular diseases (40%), neoplasms (22.5%), and respiratory diseases (10%). In practically all of the target variable strata, elderly men with fair or poor SRH showed a higher risk of dying as compared to those with excellent or good SRH. In the final model, the variables fair/poor SRH (hazard risk=HR=1.88, 95% confidence interval=95%CI=1.29-2.72), age (HR=1.05, 95%CI=1.03-1.08), public health system as the regular source of care (HR=1.69, 95%CI=1.10-2.60), current smoking (HR=1.94, 95%CI=1.24-3.04), and acute cardiovascular disease (HR=1.62, 95%CI=1.06-2.47) were associated with mortality. We concluded that SRH proved to be a predictive variable for mortality in elderly men after 2 years of follow-up, with nearly a twofold risk of death among men that reported fair or poor health, after adjusting for age, regular use of the public health system, current smoking, and acute cardiovascular disease. Given the importance of poor SRH for predicting mortality in elderly men, health services should incorporate this indicator into health assessments in this population.
Revista Brasileira em Promoção da Saúde | 2013
Karla Geovanna Moraes Crispim; Rita de Cássia Rodrigues; Aldo Pacheco Ferreira; Inês Echenique Mattos; L M Santiago
Objetivo: Descrever os achados audiologicos (tipo, configuracao audiometrica, grau de perda auditiva) e sua associacao com sexo e faixa etaria em sujeitos com idade igual ou superior a 60 anos, atendidos em ambulatorio de especialidades de Manaus. Metodos: Estudo epidemiologico transversal, descritivo, realizado com o universo de idosos que se submeteram a audiometria no periodo de janeiro a dezembro de 2010, sendo um total de 574 sujeitos. Para classificacao do tipo, grau e configuracao da perda auditiva, utilizaram-se os criterios adotados por Santos & Russo; Davis & Silverman e Silman & Silverman, respectivamente. Realizou-se analise estatistica atraves de medidas de tendencia central, dispersao e distribuicoes de frequencia. Para verificacao de diferencas estatisticamente significativas, utilizou-se o teste qui-quadrado, com nivel de significância de 5% (p≤0,05). Resultados: Observou-se prevalencia de 94,4 % (n=542) de perda auditiva, predominantemente do tipo sensorioneural (85,5%; n=491) e grau leve (60%; n=188) no sexo feminino e grau moderado ou maior no sexo masculino (50%; n=130), de configuracao descendente (54,2%; n=311) em ambos os sexos. O percentual de normalidade foi baixo, sendo de 261 (3,4%) para os homens e 313 (7,3%) para as mulheres. Conclusao: A prevalencia de perda auditiva aumentou com a idade, sendo igual a 100% nos individuos de 80 anos ou mais, e os homens apresentaram os piores limiares auditivos. Ha necessidade de maior conhecimento sobre a deficiencia auditiva no idoso, sendo necessarios estudos adicionais de base populacional e multicentricos com o objetivo de subsidiar politicas publicas.
Journal of Epidemiology and Community Health | 2011
L L Luz; L M Santiago; Inês Echenique Mattos; D B Ferreira; J F S da Silva
Introduction While incidence and mortality rates for most cancers are decreasing in developed countries, they are increasing in the less developed. Prostate cancer is becoming one of the most frequent cancers in men. The aim of this study was to analyse trends of mortality for prostate cancer in elder Brazilians. Methods All deaths with prostate cancer as the underlying cause, occurring during 1980–2008, in the 27 Brazilian States, in men aged 60 years or more, were identified in the Mortality Information System, a population-based nationwide registry. Population data was obtained from the Brazilian Institute of Geography and Statistics. Trends were analysed through polynomial regression models, using adjusted and age-specific annual rates of mortality for each State. Results Prostate cancer mortality has been increasing in all Brazilian States, although some showed a certain pattern of stability for the more recent years. There was considerable regional variability in the magnitude of the annual increments, varying from 1.30 to 6.25 deaths per 100 000 men/year. Regarding trends by age groups, patterns were similar to those observed for the group as a whole. Conclusion Incidence of prostate cancer has greatly increased over the last decades, following the advent of the prostate-specific antigen test. Consequently, interpreting temporal trends in mortality has become difficult. It remains unclear to what extent the increasing mortality rates are due to detection of the disease or are representing a rise in its incidence. The increase in mortality observed in Brazil requires further monitoring.
Journal of Epidemiology and Community Health | 2011
L M Santiago; L L Luz; Inês Echenique Mattos
Introduction The adoption of unhealthy western lifestyles has contributed to changes in mortality patterns in developing countries. The aim of this study was to evaluate associated causes of death in older men in a medium-size Brazilian city. Methods The study was based on a cohort of 2859 older men living in Juiz de Fora, Brazil, followed from 2006 to 2010. All death certificates were retrieved from the Mortality Information System of the city. Underlying and associated causes of death were coded according to the 10th International Classification of Diseases. Results There were 298 deaths and mean age at death was 73.4 years. Diseases of the circulatory system (I00–I99) corresponded to 108 (36.2%) deaths and its major associated causes were other circulatory diseases, diseases of the respiratory system (J00–J99) and infectious and parasitic diseases (A00–B99). Neoplasms corresponded to 65 deaths (21.8%) and predominant associated causes were respiratory diseases, mainly pneumonias, and infectious and parasitic diseases. Diseases of the respiratory system corresponded to 44 (14.8%) deaths and infectious and parasitic diseases were the main associated cause. These three groups comprised 72.8% of the underlying causes in the cohort. Conclusion Circulatory and respiratory diseases and neoplasms were major causes of mortality in this cohort and also represent an important public health problem in Brazil. The influence of a westernised life style is probably reflected in this pattern of chronic diseases. Although not as important, infectious and parasitic diseases are still present as associated causes and likely worsening health conditions in this cohort.
Journal of Epidemiology and Community Health | 2011
L L Luz; L M Santiago; Inês Echenique Mattos
Introduction The Comprehensive Geriatric Assessment (CGA) is an evaluation conducted on older people to detect limitations of health in multiple domains. However, CGA is a time-consuming assessment and so the use of abbreviated screening instruments, as the Vulnerable Elders Survey (VES-13) has been proposed. The purpose of this study was to evaluate the performance of the VES-13 in elders who live in Brazilian long-stay institutions. Methods This is a study with elderly residents of long-stay institutions in four Brazilian cities. The assessment of functional, emotional and cognitive domains was performed with CGA and with VES-13. Individuals were scored separately with both instruments and classified accordingly. The proportion of positives identified in each domain with the CGA was compared to that of the VES-13. The characteristics of the targeted group were compared with those not selected using the χ2 test. Results These are preliminary results for 340 elders. Mean age was 75.5 years and 304 (89.4%) were considered as vulnerable (score ≥3). VES-13 identified correctly 90.5% of the elders with cognitive impairment, 99.3% of those with dependence in ADL, 99.5% of those in IADL and 86.9% of those who had depression. Compared to those not selected targeted individuals were older (80 years or more), male, had cognitive impairment and were dependent in ADL and in IADL (p<0.001). Conclusions VES-13 performed well as a screening instrument in this particular setting, identifying the majority of those elders with functionality problems, cognitive impairment and depression and who would need further evaluation with CGA.
Journal of Epidemiology and Community Health | 2011
L M Santiago; Inês Echenique Mattos; L L Luz
Introduction Self-reported health is a perception based on an individual interpretation of physical aspects, mental status and expectations and is considered a good predictor of mortality among old people in developed countries. The aim of this study was to evaluate the role of self-reported health as a predictor of mortality in elderly men in a developing country. Methods The study population consisted of 2875 elderly men of a medium size city in Southeast Brazil, who were followed for 4 years or until the date of their death, whichever occurred first. Individuals alive at the end of follow-up were censored. Multivariate analysis was performed through Cox regression models. Variables presenting statistically significant associations with mortality in bivariate analysis where entered into the models. Results During the follow-up, 298 deaths occurred. Elders with self-reported poor health presented a greater risk of death, compared to those with self-reported good/excellent health in almost all stratus of the analysed variables. In the final model, poor self-reported health (HR 1.54 95% CI 1.21 to 1.96), age (HR 1.07 95% CI 1.06 to 1.09), marital status (HR 1.32 95% CI 1.04 to 1.69), current use of cigarette smoking (HR 1.94 95% CI 1.24 to 2.62), cardiovascular disease (HR 1.62 95% CI 1.06 to 2.47), diabetes (HR 1.53 95% CI 1.14 to 2.04) and recent hospitalisation (HR 1.50 95% CI 1.15 to 1.95) were independently associated to mortality. Conclusion Self-reported health was a good predictor of mortality in this population of elderly men, even when adjusted for other independent variables. It is important that healthcare services incorporate this indicator in the health evaluation of old people.
Journal of Epidemiology and Community Health | 2011
L L Luz; J F Santos-Silva; L M Santiago; Inês Echenique Mattos
Introduction Mortality rates of prostate cancer show regional variations in Brazil. The heterogeneous dietary profile and the distribution of agricultural practices could, at least partially, explain the observed patterns. This ecological study aimed to identify associations between selected dietary, agricultural variables and mortality rates for prostate cancer in men aged 60 or more in selected Brazilian States. Methods States selected for study were the main agricultural producers in Brazil. Dietary (characterised as per capita kcal/day consumption of food groups) and agricultural variables were selected in the literature. Agricultural data were obtained from the National Agricultural Census and dietary data from the National Survey by Household Sampling. Multiple linear regression were used to analyse the correlations between mortality rates and the selected variables. Results Age-adjusted mortality rates varied from 112.79 to 174.92 per 100 000. The final multivariate model was capable of explaining 99.9% of the variation in mortality rates. Number of agricultural establishments, hectares planted with permanent crops, and hectares planted with temporary crops showed positive associations with mortality rates, as well as vegetable consumption, percentage of population aged 60 or more, and percentage of population having had medical consultation in the last 12 months. Negative associations were observed for total calories, consumption of oils and fats and percentage of population with health plan coverage. Conclusions These results suggest that differences in long-term dietary habits and exposures to agricultural hazards could influence patterns of prostate cancer among Brazilian elders. Further epidemiologic studies are needed to clarify these possible associations.
Journal of Epidemiology and Community Health | 2011
L L Luz; Inês Echenique Mattos; D B Ferreira; L M Santiago
Introduction Incidence and mortality of haematological malignancies have been increasing in Brazil, as a great number of individuals reach the age of 60 years. The aim of this study was to analyse patterns of mortality from haematological cancers in older Brazilians. Methods Deaths from haematological malignancies in individuals of 60 or more years in 11 States were identified in the Mortality Information System, a population-based nationwide registry. Population data was obtained from the Brazilian Institute of Geography and Statistics. Polynomial regression was used to analyse trends in age-adjusted and age-specific mortality rates. Results Leukaemia showed the highest rates, varying from 11.96 to 17.58 per 100 000. Trends of increment were observed in three States, while a declining trend was observed in one. Mortality rates of Non-Hodgkin lymphoma ranged between 6.64 and 16.35 per 100 000 and presented regional variability, with declining trends in South and Southeast States and increments in Central-West States. Mortality rates for myeloma showed steady increasing trends in four States. For Hodgkins disease, declining trends were seen in two States. Trends of increment were observed for leukaemia and Non-Hodgkin lymphoma in the 80 or more age-group. Conclusions The Southeast is the most industrialised Brazilian region with major petroleum exploitation and petroleum-based industries. The South and the Central-West are areas of extensive agriculture. Although the aetiology of these malignancies is still largely undefined, they have some common potential risk factors (solvents, pesticides) which could have contributed to the observed trends. These findings need further analysis to better characterise mortality patterns.
Journal of Epidemiology and Community Health | 2011
L L Luz; L M Santiago; J F Santos da Silva; P H de Oliveira; Inês Echenique Mattos; L C Alves
Introduction Health conditions and functionality problems related to ageing affect the ability to live independently, leading to the placement of elders in a long-stay institution. This phenomenon has been increasing in Brazil. This study analyzes functional dependence and its associated factors in this population group. Methods This is a cross-sectional study with elderly residents of long-stay institutions in four Brazilian cities. The studys questionnaire included socio-demographic and health-related variables and the assessment of functioning, cognition and mood with scales widely used in elderly populations. The population profile was characterised and the prevalence of dependence in activities of daily life (ADL) and instrumental activities of daily life (IADL) was estimated. Bivariate and multivariate analyses were performed with Poisson regression. Results These are preliminary results for 340 elders. The mean age was 75.5 years, most were men, 0–4 years of schooling and <5 years of institutionalisation. ADL dependence was 40.0% and IADL 58.5%. Female (PR 2:41, 95% CI 1.84 to 3.17), 80 or more years (PR 3.35; 95% CI 1.37 to 8.17), with very poor/poor health (PR 3.28; 95% CI 1.23 to 8.72) and cognitive impairment (PR 2.66; 95% CI 1.19 to 5.95) had high probability of dependence in ADL. Female (PR 3.55; 95% CI 2.31 to 5.45), 80 or more years (PR 5.47, 95% CI 2.26 to 13.25), illiterate (PR 4.89, 95% CI 2.54 to 9.43) and with cognitive impairment (RP 2.55; 95% CI 1.14 to 5.73) had high probability of dependence in IADL. Conclusions The high prevalence of functional dependence indicates the need for social and healthcare public policies aimed at this specific group in Brazil.