L. Requena Caballero

Clear-Cell Syringoma

Clear-cell syringoma is a histologic variant of syringoma that is otherwise clinically indistinguishable from ordinary syringoma. This variant is formed by cells that have pale or clear cytoplasm as a

Clear cell syringoid eccrine carcinoma

: A case of syringoid eccrine carcinoma (SEC) is reported. The tumor was mainly formed by clear cells laden with glycogen. This feature, rarely found in syringoma, had not previously been reported in SEC. The authors assume that SEC is an infiltrating and locally destructive but not metastasizing neoplasm. They propose that SEC is a clinicopathologic entity with a histopathologic spectrum from the more differentiated syringomatoid ones to so-called primary cutaneous adenoid cystic carcinoma. A possible nexus between the more syringomatoid cases and the sclerosing sweat duct (syringomatous) carcinoma is also discussed.

Pigmented follicular cyst.

This report describes the clinical and histopathologic characteristics of a pigmented follicular cyst. Clinically, it was a blue intracutaneous nodule that simulated a blue nevus. Nevertheless, the histopathologic examination showed in the mid dermis an epithelial cyst whose wall comprised a layer of stratified squamous epithelium with infundibular keratinization and whose lumen contained laminated keratin and many pigmented terminal hair shafts. The differential diagnosis with other epithelial cysts containing hair shafts in their cavities, mainly the eryptive vellus hair cyst, is discussed.