Larisa Kunitskaya

Block-Copolymers of Polyacrylamide with Poly(Ethylene Oxide) Forming Intramolecular Polycomplexes

Diblock-copolymers of polyacrylamide (PAA) and monomethyl ethers of poly(ethylene glycol) (MEPEG) of different molecular weights (M vMEPEG = 7.5 ⋅ 102 − 5 ⋅ 103) are obtained. The positive matrix effect depending on the length of MEPEG chains is revealed. The copolymerization kinetics is measured by dilatometry and compared with that of AA homopolymerization. Molecular parameters of synthesized copolymers are determined by size exclusion chromatography (SEC). Structural investigations are carried out by differential scanning calorimetry (DSC).

Donor Oligomer Based Film Heterostructures Doped with Squarilium Organic Dye and their Photoelectric Properties

The new heterostructures comprising a squarylium dye (SQ) film deposited onto a oligo-N-epoxypropylcarbazole (OGC) film have been created, and their photoconducting, photodielectric, and photovoltaic properties have been studied. The OGC/SQ heterostructures exhibit the photodiode properties. It is concluded that the p–n junction in these heterostructures is ensured by the hole character of conductivity in the oligomer and the bipolar conductivity of the deposited dye film.

Double Hydrophilic Block Copolymers for Doxorubicin Delivery

The anionic derivative of asymmetric triblock copolymer containing biocompatible chemically complementary polyacrylamide and poly(ethylene oxide) (PAAm-b-PEO-b-PAAm) was obtained. The micellization of the initial (TBC) and modified (TBC-COOH) copolymer samples in aqueous solution were investigated. The similar values of the critical micellization concentration and the Gibbs free micellization energy for initial and modified TBCs were found. The anticancer effects of the doxorubicin (DOX)-loaded micelles of the initial and modified triblock copolymers were studied. The fact of higher efficacy of DOX/TBC and DOX/TBC-COOH compositions in compare with pure DOX was determined and discussed.

The Self-Assembly of Diblock Copolymers MePEG-b-PAAm into Micellar Structures and Their Interaction with Doxorubicin

The micellization of asymmetric diblock copolymers (DBC) MePEG-b-PAAm formed by monomethoxy-poly(ethylene)oxide (MePEG) and polyacrylamide (PAAm) has been studied in water, a water/alcohol mixture, and a NaCl solution. The effect of added NaCl on the critical micellization concentration of DBC water solutions was examined. The interaction between DBC and antitumor drug doxorubicin is discussed. The analysis of the UV spectrum of doxorubicin is performed.

Block copolymers containing polyacrylamide and polyacrylic acid: Bulk structure and hydrogen bonds system

ABSTRACT Asymmetric block copolymers PAAc-b-PAAm (DBCs) and PAAm-b-PAAc-b-PAAm (TBCs) comprised poly(acrylic acid) blocks of constant chain length and polyacrylamide blocks of variable chain length were synthesized using RAFT/MADIX technique. Their properties in a bulk state were studied by differential scanning calorimetry and the hydrogen bond system was investigated by Fourier transform infrared spectroscopy. It was found that DBCs and TBCs possess a homogeneous amorphous structure, whose temperatures of glass transition and destruction beginning increased with growth of PAAm block length. The H-bond system between PAAc and PAAm blocks was most developed in TBC sample and formed manly by the mixed cyclic dimmers of carboxyl and amide groups.

Nanostructured Triblock Copolymers with Chemically Complementary Components and their Ionic Conductivity

A series of structural and electrochemical studies of the triblock copolymers (TBCs) based on poly(ethylene oxide) ( M n = 14 and 35 kDa) and polyacrylamide (PAAm- b -PEO- b -PAAm), which formed the intramolecular polycomplexes, were carried out using nuclear magnetic resonance, differential scanning calorimetry, wide-angle and small-angle X-ray scattering, and impedance spectroscopy. The combination of the amorphous mass-fractal-organized structure of the copolymers with high level of the ionic conductivity of pure TBCs and their compositions with the couple KI/I 2 and LiPF 6 salt was established. Possible reasons for the effects in the context of applications of TBC compositions in solar cells and lithium batteries are discussed.