Lars Willmes
Leiden University
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Publication
Featured researches published by Lars Willmes.
congress on evolutionary computation | 2003
Lars Willmes; Thomas Bäck; Yaochu Jin; Bernhard Sendhoff
Neural networks and Kriging method are compared for constructing fitness approximation models in evolutionary optimization algorithms. The two models are applied in an identical framework to the optimization of a number of well known test functions. In addition, two different ways of training the approximators are evaluated: in one setting the models are built off-line using data from previous optimization runs and in the other setting the models are built online from the data available from the current optimization.
Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2012
Frank R. Datema; Ana Moya; Peter Krause; Thomas Bäck; Lars Willmes; Ton P. M. Langeveld; Robert J. Baatenburg de Jong; Henk Blom
Electronic patient files generate an enormous amount of medical data. These data can be used for research, such as prognostic modeling. Automatization of statistical prognostication processes allows automatic updating of models when new data is gathered. The increase of power behind an automated prognostic model makes its predictive capability more reliable. Cox proportional hazard regression is most frequently used in prognostication. Automatization of a Cox model is possible, but we expect the updating process to be time‐consuming. A possible solution lies in an alternative modeling technique called random survival forests (RSFs). RSF is easily automated and is known to handle the proportionality assumption coherently and automatically. Performance of RSF has not yet been tested on a large head and neck oncological dataset. This study investigates performance of head and neck overall survival of RSF models. Performances are compared to a Cox model as the “gold standard.” RSF might be an interesting alternative modeling approach for automatization when performances are similar.
EA'07 Proceedings of the Evolution artificielle, 8th international conference on Artificial evolution | 2007
Riccardo Fanciulli; Lars Willmes; Janne Savolainen; Peter van der Walle; Thomas Bäck; Jennifer Lynn Herek
This study describes first steps taken to bring evolutionaryoptimization technology from computer simulations to real world experimentationin physics laboratories. The approach taken considers a wellunderstood Laser Pulse Compression problem accessible both to simulationand laboratory experimentation as a test function for variants ofEvolution Strategies. The main focus lies on coping with the unavoidablenoise present in laboratory experimentation. Results from simulations arecompared to previous studies and to laboratory experiments.
parallel problem solving from nature | 2002
Boris Naujoks; Lars Willmes; Thomas Bäck; Werner Haase
A new approach for multi criteria design optimisation is presented in the paper. The problem tackled with this approach is the 2- dimensional design of an aircraft wing. To carry the derandomized step size control also to the multi criteria applications, four different selection schemes are proposed. Furthermore, we present a new method for averaging results of multi objective evolutionary algorithms. This method is then used to compare the results achieved with the proposed algorithms.
Lecture Notes in Computer Science | 2004
Thomas Bäck; Ron Breukelaar; Lars Willmes
Evolving solutions rather than computing them certainly represents an unconventional programming approach. The general methodology of evolutionary computation has already been known in computer science since more than 40 years, but their utilization to program other algorithms is a more recent invention. In this paper, we outline the approach by giving an example where evolutionary algorithms serve to program cellular automata by designing rules for their iteration. Three different goals of the cellular automata designed by the evolutionary algorithm are outlined, and the evolutionary algorithm indeed discovers rules for the CA which solve these problems efficiently.
Lecture notes in artificial intelligence | 2008
Nicolas Monmarché; Riccardo Fanciulli; Lars Willmes; El-Ghazali Talbi; Janne Savolainen; Pierre Collet; Marc Schoenauer; P. van der Walle; Evelyne Lutton; Thomas Bäck; Jennifer Lynn Herek
This study describes first steps taken to bring evolutionaryoptimization technology from computer simulations to real world experimentationin physics laboratories. The approach taken considers a wellunderstood Laser Pulse Compression problem accessible both to simulationand laboratory experimentation as a test function for variants ofEvolution Strategies. The main focus lies on coping with the unavoidablenoise present in laboratory experimentation. Results from simulations arecompared to previous studies and to laboratory experiments.
Computational Fluid and Solid Mechanics 2003#R##N#Proceedings Second MIT Conference on Compurational Fluid and Solid Mechanics June 17–20, 2003 | 2003
Lars Willmes; Thomas Bäck
Publisher Summary Computer simulations of complex engineering problems have become a standard tool of modern product development and design. The increasing computational power at modest costs leads to a growing interest in directly using computer simulation codes for automatic product optimization. Traditional numerical optimization methods have some drawbacks that make them difficult to use with complex simulation software. Gradient-based methods are always local optimizers, thus requiring additional methods such as random restarts to find global optima. Evolutionary optimization is a way to overcome some of these limitations. This chapter presents a paper that introduces evolution strategies as a robust and fault-tolerant optimization method, which does not rely on gradients, is easily adaptable to massively parallel computing systems and can be used for single and multiple-criteria optimization. It describes a complex and aerodynamical test problem that was solved by an evolution strategy. This paper introduces the basic elements of evolution strategies and addresses their important features such as self adaptation, robustness, and multiprocessor implementations.
Archive | 2000
Lars Willmes; Werner Haase; Martin Schutz
Head & Neck Oncology | 2012
Frank R. Datema; Ana Moya; Peter Krause; Thomas Bäck; Lars Willmes; Ton P. M. Langeveld; Robert J. Baatenburg de Jong; Henk Blom
Informatica (slovenia) | 2004
Thomas Bäck; Lars Willmes; Peter Krause