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Dive into the research topics where Laura Masi is active.

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Featured researches published by Laura Masi.


Clinical Cases in Mineral and Bone Metabolism | 2017

The LARO-MEN1 study: a longitudinal clinical experience with octreotide Long-Acting Release in patients with Multiple Endocrine Neoplasia type 1 Syndrome

F Cioppi; Luisella Cianferotti; Laura Masi; F Giusti; Ml Brandi

Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumoral syndrome, featured by a combination of neoplasms of various endocrine and nonendocrine tissues. Approximately 33% of MEN1-related deaths are due to the malignant behaviour of well-differentiated neuroendocrine tumors (NETs), for which a preventive surgical treatment is not feasible. Somatostatin analogues (SSA) have been employed in the treatment of NETs in the stage of advanced or metastatic disease, in order to control the growth and secretion of tumor lesions. A longitudinal, open label study named LARO-MEN1 was undertaken in order to assess whether early medical treatment with long-acting SSA could act as a preventive approach in small MEN1-related gastroenteropancreatic (GEP) NETs. Thirty consecutive patients affected by MEN1 were screened and 8 patients with small (<2 cm) NETs and abnormal laboratory values of at least one of the GEP hormones were administered octreotide acetate slow-release formulation (LAR) (10 mg i.m. every 28 days). Octreotide LAR was effective in decreasing GEP hormones and overall safe in the majority of patients up to six years of treatment, maintaining the disease stable also in terms of tumor size. The positive outcomes of this study in MEN1 patients reinforce the results obtained in advanced NETs on the use of SSA, opening to the opportunity for preventive use of octreotide LAR, aimed to delay or even avoid surgery in these patients.


Journal of Bone and Mineral Research | 2009

Biosynthesis of bone sialoprotein by a human osteoclast-like cell line (FLG 29.1)

Laura Masi; Maria Luisa Brandi; Pamela Gehron Robey; Clara Crescioli; Juan Carlos Calvo; Pietro Antonio Bernabei; Janet M. Kerr; Masaki Yanagishita


Clinical and Experimental Rheumatology | 2013

Can fibroblast growth factor (FGF)-23 circulating levels suggest coronary artery abnormalities in children with Kawasaki disease?

Laura Masi; Francesco Franceschelli; Gigliola Leoncini; A Gozzini; Donato Rigante; F. La Torre; M. Matucci Cerinic; M. L. Brandi; Fernanda Falcini


Archive | 2004

Genetic aspects of Paget’s disease of bone

Alberto Falchetti; Francesca Marini; Laura Masi; Maria Luisa Brandi


ESCEO-IOF | 2013

A New Fgf23 Gene Polymorphism: Possible Role In the Pathogenesis of the Development of Extraskeletal Calcifications?

Gemma Marcucci; Laura Masi; Francesca Giusti; Loredana Cavalli; Francesco Franceschelli; Gigliola Leoncini; Caterina Fossi; Maria Luisa Brandi


Archive | 2009

Short communication Germline mutations in MEN1 and BRCA1 genes in a woman with familial multiple endocrine neoplasia type 1 and inherited breasteovarian cancer syndromes: a case report

Laura Papi; Domenico Palli; Laura Masi; Anna Laura Putignano; Caterina Congregati; Ines Zanna; Francesca Marini; Francesca Giusti; Ettore Luzi; Francesco Tonelli; Maurizio Genuardi; Maria Luisa Brandi; Alberto Falchetti


28th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research | 2006

Haplotype analysis of two pairs of unrelated Italian families affected by Paget's disease of bone, exhibiting different geographical origins and two different mutations of p62/sequestosomel gene, supports the evidence for common founders.

Alberto Falchetti; Marco Di Stefano; Francesca Marini; Laura Masi; Francesca Giusti; C. Cepollaro; Ettore Luzi; Valentina Martineti; Carmelo Mavilia; Debora Strigoli; Simona Bergui; Gianluca Isaia; Maria Luisa Brandi


Archive | 2005

Relatioship of volumetric BMD and structural parameters to ER GENE polymorphisms in men

C. Cepollaro; Fulvio Lauretani; Alessia Gozzini; Laura Masi; Alberto Falchetti; F. Del Monte; Annalisa Tanini; Anna Maria Corsi; Stefania Bandinelli; M. L. Brandi


Archive | 2005

Results of a national survey on multiple endocrine neoplasia syndrome type 1 in Italy: a macroaggregateanalysis

Alberto Falchetti; Francesca Marini; Francesca Del Monte; Laura Masi; Silvia Carbonell Sala; Valentina Ghinoi; Francesco Franceschelli; Annalisa Tanini; Francesco Tonelli; Maria Luisa Brandi


Archive | 2005

A new mutation of PHEX GENE in patient with hyperphospaturia and hypercalciuria

S. Carbonell Sala; Alessia Gozzini; Alberto Falchetti; E. Croppi; F. Cioppi; Laura Masi; Annalisa Tanini; M. L. Brandi

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