Laura Masi
National Institutes of Health
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Publication
Featured researches published by Laura Masi.
Clinical Cases in Mineral and Bone Metabolism | 2017
F Cioppi; Luisella Cianferotti; Laura Masi; F Giusti; Ml Brandi
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumoral syndrome, featured by a combination of neoplasms of various endocrine and nonendocrine tissues. Approximately 33% of MEN1-related deaths are due to the malignant behaviour of well-differentiated neuroendocrine tumors (NETs), for which a preventive surgical treatment is not feasible. Somatostatin analogues (SSA) have been employed in the treatment of NETs in the stage of advanced or metastatic disease, in order to control the growth and secretion of tumor lesions. A longitudinal, open label study named LARO-MEN1 was undertaken in order to assess whether early medical treatment with long-acting SSA could act as a preventive approach in small MEN1-related gastroenteropancreatic (GEP) NETs. Thirty consecutive patients affected by MEN1 were screened and 8 patients with small (<2 cm) NETs and abnormal laboratory values of at least one of the GEP hormones were administered octreotide acetate slow-release formulation (LAR) (10 mg i.m. every 28 days). Octreotide LAR was effective in decreasing GEP hormones and overall safe in the majority of patients up to six years of treatment, maintaining the disease stable also in terms of tumor size. The positive outcomes of this study in MEN1 patients reinforce the results obtained in advanced NETs on the use of SSA, opening to the opportunity for preventive use of octreotide LAR, aimed to delay or even avoid surgery in these patients.
Journal of Bone and Mineral Research | 2009
Laura Masi; Maria Luisa Brandi; Pamela Gehron Robey; Clara Crescioli; Juan Carlos Calvo; Pietro Antonio Bernabei; Janet M. Kerr; Masaki Yanagishita
Clinical and Experimental Rheumatology | 2013
Laura Masi; Francesco Franceschelli; Gigliola Leoncini; A Gozzini; Donato Rigante; F. La Torre; M. Matucci Cerinic; M. L. Brandi; Fernanda Falcini
Archive | 2004
Alberto Falchetti; Francesca Marini; Laura Masi; Maria Luisa Brandi
ESCEO-IOF | 2013
Gemma Marcucci; Laura Masi; Francesca Giusti; Loredana Cavalli; Francesco Franceschelli; Gigliola Leoncini; Caterina Fossi; Maria Luisa Brandi
Archive | 2009
Laura Papi; Domenico Palli; Laura Masi; Anna Laura Putignano; Caterina Congregati; Ines Zanna; Francesca Marini; Francesca Giusti; Ettore Luzi; Francesco Tonelli; Maurizio Genuardi; Maria Luisa Brandi; Alberto Falchetti
28th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research | 2006
Alberto Falchetti; Marco Di Stefano; Francesca Marini; Laura Masi; Francesca Giusti; C. Cepollaro; Ettore Luzi; Valentina Martineti; Carmelo Mavilia; Debora Strigoli; Simona Bergui; Gianluca Isaia; Maria Luisa Brandi
Archive | 2005
C. Cepollaro; Fulvio Lauretani; Alessia Gozzini; Laura Masi; Alberto Falchetti; F. Del Monte; Annalisa Tanini; Anna Maria Corsi; Stefania Bandinelli; M. L. Brandi
Archive | 2005
Alberto Falchetti; Francesca Marini; Francesca Del Monte; Laura Masi; Silvia Carbonell Sala; Valentina Ghinoi; Francesco Franceschelli; Annalisa Tanini; Francesco Tonelli; Maria Luisa Brandi
Archive | 2005
S. Carbonell Sala; Alessia Gozzini; Alberto Falchetti; E. Croppi; F. Cioppi; Laura Masi; Annalisa Tanini; M. L. Brandi