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Archive | 1997

Targeted and Sustained-Release Delivery Concepts in Gene Therapy

Robert W. Schroff; Lawrence L. Kunz

There are presently a number of applications for gene therapy, and a number of promising approaches. This chapter describes a variety of methodologies that could potentially be employed to address some of the deficiencies of current delivery vehicles employed in gene therapy. In particular, approaches that may provide for specific targeting or the sustained release of therapeutically administered genetic material are discussed.


Archive | 2001

THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS

Lawrence L. Kunz; Peter G. Anderson


Archive | 1998

Prevention and treatment of cardiovascular pathologies

David J. Grainger; James C. Metcalfe; Lawrence L. Kunz; Robert W. Schroff; Peter L. Weissberg


Archive | 1996

Prevention and treatment of cardiovascular pathologies with tamoxifen analogues

David J. Grainger; James C. Metcalfe; Lawrence L. Kunz; Robert W. Schroff


Archive | 1998

Use of cytoskeletal inhibitors for the prevention of restenosis

Lawrence L. Kunz; Richard A. Klein; John M. Reno


Archive | 1994

Therapeutic inhibitors of vascular smooth muscle cells

Lawrence L. Kunz; Richard A. Klein


Archive | 1998

Implantable device comprising taxol in crystalline form for the inhibition or prevention of restenosis

Lawrence L. Kunz; Richard A. Klein; John M. Reno


Archive | 1998

Dosage form comprising taxol in crystalline form

Richard A. Klein; Lawrence L. Kunz; John M. Reno


Journal of the American College of Cardiology | 1995

984-23 Efficacy of Cytochalasin B in Inhibiting Coronary Restenosis Caused by Chronic Remodeling After Balloon Trauma in Swine

Lawrence L. Kunz; Lauren M. Tatalick; Peter G. Anderson; Robert W. Schroff; Gary S. Roubin


Archive | 1998

Implantierbare Vorrichtung enthaltend Taxol in kristalliner Form zur Hemmung oder Vorbeugung der Restenose

Lawrence L. Kunz; Richard A. Klein; John M. Reno

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