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Lawrence R. Koupal

Merck & Co.

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Featured researches published by Lawrence R. Koupal.

Cancer Research | 1995

Epothilones, a New Class of Microtubule-stabilizing Agents with a Taxol-like Mechanism of Action

Daniel M. Bollag; Patricia A. Mcqueney; Jian Zhu; Otto D. Hensens; Lawrence R. Koupal; Jerrold M. Liesch; Michael A. Goetz; Elias Lazarides; Catherine M. Woods

Endocrinology | 1989

A Structurally Unique, Potent, and Selective Oxytocin Antagonist Derived from Streptomyces silvensis

Douglas J. Pettibone; Bradley V. Clineschmidt; Paul S. Anderson; Roger M. Freidinger; George F. Lundell; Lawrence R. Koupal; Cheryl D. Schwartz; Joanne M. Williamson; Michael A. Goetz; Otto D. Hensens; Jerrold M. Liesch; James P. Springer

Archive | 1989

Renin-inhibitory pepstatin phenyl derivatives

Leeyuan Huang; Joseph Dunn; Lawrence R. Koupal; Jerrold M. Liesch; Otto D. Hensens; H. Boyd Woodruff

The Journal of Antibiotics | 1991

L-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination.

Otto D. Hensens; Robert P. Borris; Lawrence R. Koupal; Charles G. Caldwell; Sara A. Currie; Akber A. Haidri; Carl F. Homnick; Susan S. Honeycutt; Susan M. Lindenmayer; Cheryl D. Schwartz; Barbara Weissberger; H. B. Woodruff; Deborah L. Zink; Lauretta Zitano; Jill M. Fieldhouse; Thomas Rollins; Martin S. Springer; James P. Springer

The Journal of Antibiotics | 1992

L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease: I. The producing organism and its fermentation

Anne W. Dombrowski; Gerald F. Bills; Glory Sabnis; Lawrence R. Koupal; Richard Meyer; John G. Ondeyka; Robert A. Giacobbe; Richard L. Monaghan; Russell B. Lingham

Archive | 1989

Oxytocin and vasopressin antagonists

Michael A. Goetz; Cheryl D. Schwartz; Lawrence R. Koupal; Jerrold M. Liesch; Otto D. Hensens; Roger M. Freidinger; Paul S. Anderson; Douglas J. Pettibone; Boyd H. Woodruff

Archive | 1991

Culture of Asperigillus versicolor and mutants thereof

Anne W. Dombrowski; Lawrence R. Koupal

The Journal of Antibiotics | 1983

Quaternary heterocyclylamino .BETA.-lactams. II. The in vitro antibacterial properties of L-640,876, a new type of .BETA.-lactam antibiotic.

Lawrence R. Koupal; Barbara Weissberger; Daniel L. Shungu; Ellen Weinberg; Hans H. Gadebusch

The Journal of Antibiotics | 1983

Quaternary heterocyclylamino beta-lactams. III. The mode of action of L-640,876 and the effect of NaCl on membrane permeability and binding.

Lawrence R. Koupal; Barbara A. Pelak; Patrick J. Cassidy; Hans H. Gadebusch

Archive | 1992

Processes for preparing cholesterol lowering compounds

Anne W. Dombrowski; Lawrence R. Koupal

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Otto D. Hensens

Merck

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Anne W. Dombrowski

Merck

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Barbara Weissberger

Merck

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Cheryl D. Schwartz

Merck

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Jerrold M. Liesch

Merck

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Hans H. Gadebusch

Merck

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James P. Springer

Iowa State University

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Robert P. Borris

Merck

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Akber A. Haidri

Merck

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Carl F. Homnick

United States Military Academy

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