Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Lech Ciszewski is active.

Publication


Featured researches published by Lech Ciszewski.


Tetrahedron Letters | 1998

Reductive alkylation of urea: A practical route to substituted ureas

Daqiang Xu; Lech Ciszewski; Tangqing Li; Olijan Repič; Thomas J. Blacklock

Abstract Conditions are disclosed for the formation of either mono- or di-substituted ureas by reductive alkylation, which are readily adaptable to large scale preparations. Dehydrating agents such as acetyl chloride or trimethylsilyl chloride effectively promote the condensation of ureas and aldehydes. Reduction of the adducts affords the mono- or di-substituted ureas in high yields.


Archive | 2008

Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid

David Hook; Thomas Ruch; Bernhard Riss; Bernhard Wietfeld; Gottfried Sedelmeier; Matthias Napp; Markus Bänziger; Steven Hawker; Lech Ciszewski; Liladhar Murlidhar Waykole


Organic Process Research & Development | 2003

An Expedient Synthesis of LAF389, a Bengamide B Analogue

David Xu; Liladhar Murlidhar Waykole; John Vincent Calienni; Lech Ciszewski; George T. Lee; Wenming Liu; Joanna Szewczyk; Kevin Vargas; Kapa Prasad; Oljan Repic; Thomas J. Blacklock


Tetrahedron Letters | 2004

Reductive alkylation of thioureas: a highly practical synthesis of unsymmetrical N,N′-disubstituted thioureas

Lech Ciszewski; Daquiang Xu; Oljan Repic; Thomas J. Blacklock


Archive | 2003

Process for preparing 2, 6-diaminopurine derivatives

Lech Ciszewski; Liladhar Murlidhar Waykole


Archive | 2008

Spiropyrrolidines and their use against hcv and hiv infection

Shawn D. Britt; Lech Ciszewski; Jiping Fu; Subramanian Karur; Yugang Liu; David Thomas Parker; Mahavir Prashad; Prakash Raman; Mohindra Seepersaud; Rui Zheng; Peichao Lu; Pascal Rigollier; Aregahegn Yifru


Organic Process Research & Development | 2006

A practical synthesis of 2-arylamino-6-alkylaminopurines from 2,6-dichloropurine

Lech Ciszewski; Liladhar Murlidhar Waykole; Mahavir Prashad; Oljan Repic


Organic Process Research & Development | 2008

Practical Synthesis of a Peptide Deformylase (PDF) Inhibitor

Yugang Liu; Mahavir Prashad; Lech Ciszewski; Kevin Vargas; Oljan Repic; Thomas J. Blacklock


Tetrahedron | 2009

Facile and practical synthesis of a cannabinoid-1 antagonist via regio- and stereoselective ring-opening of an aziridinium ion

Edwin Bernard Villhauer; Wen-Chung Shieh; Zhengming Du; Kevin Vargas; Lech Ciszewski; Yansong Lu; Michael J. Girgis; Melissa Lin; Mahavir Prashad


Archive | 2009

Hemifumarate salt of 1-[4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl]-azetidine-3-carboxylic acid

Lech Ciszewski; La Cruz Marilyn De; Piotr H. Karpinski; Michael Mutz; Christian Riegert; Caspar Vogel; Ricardo Schneeberger

Collaboration


Dive into the Lech Ciszewski's collaboration.

Researchain Logo
Decentralizing Knowledge