Lechosław P. Chmielik
Medical University of Warsaw
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Featured researches published by Lechosław P. Chmielik.
International Journal of Pediatric Otorhinolaryngology | 2012
Eliza Brożek-Mądry; Lechosław P. Chmielik; Adam Gałązka; Joanna Rogulska; Magdalena Frąckiewicz; Agnieszka Biejat
INTRODUCTION The mechanisms of inflammatory response occurring in chronic rhinosinusitis in children are multifactorial. Besides the history and a physical examination, amongst diagnostic tools there are cytological and bacteriological examinations. OBJECTIVES 1 Determining the nature of the bacterial flora present in the nasal cavities and paranasal sinuses in children with chronic rhinosinusitis amongst patients of The Department of Paediatric Otolaryngology,Warsaw Medical University. 2 Determining the relation between bacterial strains and cytological examination of nasal mucosa in children with chronic rhinosinusitis. MATERIALS AND METHODS The study group included 64 patients with chronic rhinosinusitis without polyps. The control group included 30 randomly chosen children. Diagnostic tests performed in both groups were: middle meatal culture and cytological examination from the inferior nasal concha and middle meatus. Statistical analysis was accomplished with Statistica 8.0. RESULTS CONCLUSIONS Damage to the respiratory epithelial surface is understood as damage to the innate immune barrier, and repeated antibiotic therapy with the subsequent repopulation of the epithelium accidentally by various bacteria can become responsible for the pathogenic effect of bacteria in chronic rhinosinusitis.
International Journal of Pediatric Otorhinolaryngology | 2009
Lechosław P. Chmielik; Magdalena Frackiewicz; Romuald Krajewski; Bogumiła Wołoszczuk-Gębicka; Mieczysław Chmielik
OBJECTIVES Juvenile angiofibroma is a benign, non-encapsulated neoplasm, consisting of vascular and connective tissue. Its main feature is a local malignancy. In its clinical course it destroys adjoining structures, without metastasizing. It appears rarely, and is mainly found in boys at puberty. Among theories about the aetiology of juvenile angiofibroma, we must consider a haematoma-like lesion, an angioma with an extended fibrous component, or type of inflammatory allergic polyp. In the development of the lesion the participation of hormonal disorders on the pituitary gland-gonad axis is also suggested. According to the latest research, juvenile angiofibroma is regarded as a developmental defect, affecting the embryonic vascular network surrounding the sphenoid bone. METHODS If the patient or his/her parents refuse blood transfusion and use of blood products, it is necessary to apply modifications in the routine perioperative treatment. In the case of the patient refusing blood and blood products transfusion because of their beliefs, it is possible to get consent to use different, highly processed products like albumins or a cryoprecipitate, as well as applying some blood-saving techniques. CONCLUSIONS 1. Removal of juvenile angiofibroma with minimal bleeding is possible. 2. Applying erythropoietin and iron preparations prior to surgery increases erythropoiesis and reduces the risks in transfusion. 3. Applying intraoperative normovolaemic haemodilution is a safe method and allows avoidance of transfusion of blood-derived products.
International Journal of Pediatric Otorhinolaryngology | 1997
Mieczysław Chmielik; Małgorzata Dębska; Marcin Partyka; Magdalena Arcimowicz; Lechosław P. Chmielik; Iwona Jakubczyk; Bartosz Wachulski
Acute subglottic laryngitis (pseudocroup) is caused by viral infection and usually occurs in children from 6 months to 4 years of age. Obese children are considered to be more susceptible to the disease. In order to evaluate the influence of nutritional status on acute subglottic laryngitis occurrence, an analysis of 193 patients was performed. A group of 70 age-matched healthy children served as the control subjects. The nutritional status of children (body weight and height) was assessed and their percentile positions on the weight and weight-height charts were determined. The recurrence of pseudocroup coexistence of allergy and breast-feeding history were considered in the study. Results of statistical analysis indicate no significant difference in weight and weight-height percentile distribution between patients group and controls. The recent changes in child nutrition might be the explanation of decreased susceptibility to pseudocroup among overfed children.
International Journal of Pediatric Otorhinolaryngology | 2015
Lechosław P. Chmielik; Karolina Raczkowska-Labuda; Lidia Zawadzka-Głos
AIM Endeavor to intraoperative macroscopic evaluation of changes in children with CRSs. Analysis of the type and incidence of pathological changes observed macroscopically during FESS was undertaken as well as an parallel attempt to correlate the level of inflammation markers with severity of disease. MATERIALS AND METHODS Retrospective analysis of case records of 153 patients of the Department of Pediatric Otolaryngology, Medical University of Warsaw, hospitalized between 2010 and 2013. During that time 106 patients with a diagnosis of chronic maxillary sinusitis required surgical intervention. 102 children (avg-aged 11.5 years) were qualified to functional endoscopic surgery. The youngest patient was 3 years old and the oldest 18. 26 patients presented the polypoid lesions of sinuses or nasals. At 19 confirmed the coexistence of sinus polyps with nasal polyps. RESULTS 76 patients had oedematous-inflammatory lesions and 26 polypoid. Among the group of listed above 26 children, 19 had either sinuses or nasal polyps. 15% children with polyps were diagnosed with cystic fibrosis and 8.0% with asthma. A common deviation in the results of morphology in children with CRSs is higher level of monocytes. Inflammation markers within the population of FESS qualified children were low. CONCLUSIONS (1) Oedematous-inflammatory lesions are frequently intraoperatively identified. (2) The CRSs without polyps is the common type of chronic sinusitis in children. (3) Nasal polyps often coexist with sinus polyps. (4) If nasal polyps are found in pediatric population then diagnosis of CF, allergy and GERD should be considered. (5) Markers of inflammation in CRSs are low.
International Congress Series | 2003
Mieczysław Chmielik; Anna Bielicka; Cezary Ranocha; Lechosław P. Chmielik
Abstract One of the first paediatric ENT centres in the world was the research group managed by Jan Danielewicz in Warsaw. It was organised on the basis of progress clinics and paediatric ENT wards, and a programme of specialisation was established. Almost simultaneously, in the sixth decade of the 20th century, centres for paediatric ENT were established in Prague, Berne, Bratislava, Budapest, Bucharest, and Sofia. In the 1970s, these were in touch with the centre for paediatric ENT in Italy, which was the pioneer in this specialty in West Europe. The effect of this contact was the creation of the European Federation of Oto-Rhino-Laryngology Societies and the International Federation of Oto-Rhino-Laryngological Societies (IFOS), and further dynamic progress in this specialisation.
International Journal of Pediatric Otorhinolaryngology | 2009
Mieczysław Chmielik; Ewa Kossowska; Eliza Brożek-Mądry; Lechosław P. Chmielik
The past few decades have been a time of rapid and constantly-accelerating development in every field of medicine, including pediatrics and laryngology. The first pediatric laryngology unit set up in Poland was in the Warsaw Kopernik Hospital in 1908, and consisted of seven beds in the surgical ward. The actual development of the specialty in Poland began in the nineteen-forties. The first modern department of Pediatric Laryngology was set up in the Mother and Child Institut in 1947, and next in Warsaw University Hospital in 1956. These two were both set up and headed by Associate Professor Jan Danielewicz who is considered to be the father of pediatric otolaryngology in Poland, and one of its co-founders in Europe. The first conference of Polish Pediatric ENT was the result of the efforts of Associate Professor Danielewicz in Zakopane, in 1958. Professors Kossowska and Danielewicz were the joint organisers of the First European Congress of Pediatric Laryngologists in Warsaw, in 1979. At present in Poland exist five Clinic of Pedatric ENT and about 25 ward of this speciality. Pediatric ENT is independent medical specialization.
Otolaryngologia Polska | 2008
Lechosław P. Chmielik; Magdalena Frąckiewicz; Mieczysław Chmielik
Summary Introduction The tumours of bony face at in children are rare. Among the most commonly found are inflammatory tumours and development anomalies. In histopathology, the most frequent fund are neuroma, fibromas, osteoma, lipomas. In inflammatory tumours there are abscess and inflammatory infiltration. Malignants tumours in this area are rare in children, but are mainly sarcomata or melanoma. Developmental tumours include cyst and fistula. Objective To analyse tumours of the bony face treated in Paediatric ENT Clinic in Warsaw. Material There were thirty cases of bony face tumours treated in Paediatric ENT Clinic in Warsaw between 2005 and 2007. Results One cases (3%) provedto be malignant, and one (3%) locally malignant. Twenty-one cases (70%) were found to be developmental tumours, three cases (10%) of abscesses, and four cases (13%) of benign tumours. Conclusions The most frequently-found tumours of bony face in children are developmental tumours. All tumours must be the subject of histopatological examination. In the case of cancers tumours it has to be established if the tumour is a primary or a metastatic. In the group analysed group the rare tumour were epithelioma, ganglioma.INTRODUCTION The tumours of bony face at in children are rare. Among the most commonly found are inflammatory tumours and development anomalies. In histopathology, the most frequent fund are neuroma, fibromas, osteoma, lipomas. In inflammatory tumours there are abscess and inflammatory infiltration. Malignants tumours in this area are rare in children, but are mainly sarcomata or melanoma. Developmental tumours include cyst and fistula. OBJECTIVE To analyse tumours of the bony face treated in Paediatric ENT Clinic in Warsaw. MATERIAL There were thirty cases of bony face tumours treated in Paediatric ENT Clinic in Warsaw between 2005 and 2007. RESULTS One cases (3%) provedto be malignant, and one (3%) locally malignant. Twenty-one cases (70%) were found to be developmental tumours, three cases (10%) of abscesses, and four cases (13%) of benign tumours. CONCLUSIONS The most frequently-found tumours of bony face in children are developmental tumours. All tumours must be the subject of histopatological examination. In the case of cancers tumours it has to be established if the tumour is a primary or a metastatic. In the group analysed group the rare tumour were epithelioma, ganglioma.
International Journal of Pediatric Otorhinolaryngology | 2008
Lechosław P. Chmielik; Jerzy Ziolkowski; Renata Koziolek; Marek Kulus; Mieczysław Chmielik
New Medicine | 2007
Lechosław P. Chmielik; Wojciech Boratyński
New Medicine | 2006
Mieczysław Chmielik; Eliza Brożek-Mądry; Lechosław P. Chmielik