Lee E. Farr

Influence of Diet on the Course of Nephrotoxic Nephritis in Rats

Conclusions 1. Under certain conditions chronic progressive nephritis follows a single insult to the kidney. 2. The course of nephrotoxic nephritis in rats can be markedly influenced by diet.

Hypoaminoacidemia in Patients with Pneumococcal Pneumonia

Summary Observations on the plasma amino acid nitrogen of 6 patients with pneumococcal pneumonia are presented. In each instance luring the acute phase of the disease the patient showed a plasma amino acid concentration significantly below the average normal value. During convalescence there was a gradual rise in the concentration of plasma amino acid nitrogen, with a return to a normal level on complete recovery from the disease. Present data indicate the normal average value to be 4.50 mg per 100 cc.

Amino Acid Nitrogen in Urine of Children with the Nephrotic Syndrome Following Intravenous Amino Acids

Summary There was no significant immediate increase in the urinary excretion per minute of non-protein nitrogen, urea plus ammonia nitrogen nor amino acid nitrogen, by 4 nephrotic children 5 to 7 years of age who had received intravenously 5 g of an amino acid mixture from casein hydrolyzed by enzymes. Therefore it appears probable that the injected amino acids are utilized for the nutritional needs of the patients.

Observations on Occurrence of Lipemia in Rats with Nephrotoxic Nephritis

Summary Significant hyperlipemia was regularly encountered in rats with severe acute nephritis induced by anti-kidney serum.

Relation of the Carrier State to Pneumococcal Peritonitis in Young Children with the Nephrotie Syndrome

Summary In 6 young children with the nephrotic syndrome who developed pneumocoecal peritonitis, the type of pneumococcus recovered from the nasopharynx was the same as that causing peritonitis. Evidence is presented which indicates that peritonitis may be caused by a strain of pneumococcus of the same specific type as that of the organism known to have been carried in the nasopharynx for a considerable time before the development of the infection; this carrier-state may persist for a prolonged period after recovery from peritonitis.