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Dive into the research topics where Lee T. Boulton is active.

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Featured researches published by Lee T. Boulton.


Organic and Biomolecular Chemistry | 2003

Asymmetric hydrogenation of a 4,4-diaryl-3-butenoate; a novel approach to sertraline

Lee T. Boulton; Ian C. Lennon; Raymond McCague

The asymmetric hydrogenation of a selectively crystallised (E)-4,4-diaryl-3-butenoate with a rhodium-PhanePhos catalyst is described, providing an intermediate to the antidepressant sertraline.


Organic Process Research & Development | 2002

Synthesis of the Potent Antiglaucoma Agent, Travoprost

Lee T. Boulton; Dean Brick; Martin E. Fox; Mark Jackson; Ian C. Lennon; Raymond McCague; Nicholas Parkin; Darren Rhodes; Graham Ruecroft


Organic Process Research & Development | 2013

The Large-Scale Synthesis of (S)-N-Boc-bis(4-fluorophenyl)alanine

Robert B. Appell; Lee T. Boulton; Edward D. Daugs; Matt Hansen; Christopher H. Hanson; Jerry Heinrich; Christel Kronig; Richard C. Lloyd; David H. Louks; Mark A. Nitz; Céline Praquin; James Andrew Ramsden; Helen Samuel; Mark R. Smit; Matthew Willets


Organic Letters | 2005

Efficient Synthesis of an Imidazole-Substituted δ-Amino Acid by the Integration of Chiral Technologies

Ian Appleby; Lee T. Boulton; Christopher J. Cobley; Catherine Hill; Mike L. Hughes; Pieter D. de Koning; Ian C. Lennon; Céline Praquin; James Andrew Ramsden; and Helen J. Samuel; Niamh Willis


Archive | 2006

Process for the synthesis of enantiomeric indanylamine derivatives

Lee T. Boulton; Ian C. Lennon; Eliezer Bahar


Tetrahedron Letters | 2005

Zinc-mediated intramolecular acyl and imino transfer reactions of aryl iodides

Lee T. Boulton; Martin E. Fox; Paul Blaise Hodgson; Ian C. Lennon


Archive | 2006

Improved process for the synthesis of enantiomeric indanylamine derivatives

Lee T. Boulton; Ian C. Lennon; Eliezer Bahar


Archive | 2006

Asymmetric hydrogenation of acyl enamides

Lee T. Boulton; Céline Praquin


Archive | 2008

Manufacture and Application of Asymmetric Hydrogenation Catalysts

Paul H. Moran; Ian C. Lennon; Lee T. Boulton; Christopher J. Cobley; Céline Praquin; James Andrew Ramsden; Graham Meek


Archive | 2007

N-protected aminoindanes and methods of their preparation

Lee T. Boulton; Céline Praquin

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Raymond McCague

Institute of Cancer Research

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