Lennox Hoyte

Quantity and distribution of levator ani stretch during simulated vaginal childbirth.

OBJECTIVE The objective of the study was to develop a model of the female pelvic floor to study levator stretch during simulated childbirth. STUDY DESIGN Magnetic resonance data from an asymptomatic nulligravida were segmented into pelvic muscles and bones to create a simulation model. Stiffness estimates of lateral and anteroposterior levator attachments were varied to estimate the impact on levator stretch. A 9 cm sphere was passed through the pelvis, along the path of the vagina, simulating childbirth. Levator response was interpreted at 4 positions of the sphere, simulating fetal head descent. The levator was color mapped to display the stretch experienced. RESULTS A maximum stretch ratio of 3.5 to 1 was seen in the posteriomedial puborectalis. Maximum stretch increased with increasing stiffness of lateral levator attachments. CONCLUSION Although preliminary, this work may help explain epidemiologic data regarding the pelvic floor impact of a first delivery. The models and simulation technique need refinement, but they may help study the effect of labor parameters on the pelvic floor.

Tumor detection in the bladder wall with a measurement of abnormal thickness in CT scans

Virtual cystoscopy is a developing technique for bladder cancer screening. In a conventional cystoscopy, an optical probe is inserted into the bladder and an expert reviews the appearance of the bladder wall. Physical limitations of the probe place restrictions on the examination of the bladder wall. In virtual cystoscopy, a computed tomography (CT) scan of the bladder is acquired and an expert reviews the appearance of the bladder wall as shown by the CT. The task of identifying tumors in the bladder wall has often been done without extensive computational aid to the expert. We have developed an image processing algorithm that aids the expert in the detection of bladder tumors. Compared with an expert observer reading the CT, our algorithm achieves 89% sensitivity, 88% specificity, 48% positive predictive value, and 98% negative predictive value.

Myofascial pain and pelvic floor dysfunction in patients with interstitial cystitis

Introduction and hypothesisThe objectives of this study are to investigate myofascial pain in patients with interstitial cystitis (IC) and to correlate myofascial exam findings with validated questionnaires.MethodsA retrospective chart review was performed on 186 patients with a diagnosis of IC from April 2007 to December 2008. Demographics, history and physical examination, and validated pelvic floor dysfunction questionnaire scores were extracted. The data was evaluated with SPSS for Windows using Spearmans rho, Mann–Whitney, and Kruskal–Wallis statistical analyses.ResultsMyofascial pain was demonstrated in 78.3% of IC patients with at least one myofascial trigger point, and 67.9% of patients had numerous areas of trigger points. Mild correlations were seen with trigger points and scores from the PUF, PFDI-20, and PFIQ-7 questionnaires.ConclusionsMyofascial pain is prevalent among IC patients and positively correlated with pelvic floor dysfunction scores. These findings support evaluation of pelvic floor myofascial pain in IC patients and suggest a possible benefit from pelvic floor therapy.

Magnetic Resonance-Based Female Pelvic Anatomy as Relevant for Maternal Childbirth Injury Simulations

Abstract:  The objectives of the study are to review the female pelvic floor anatomy relevant to childbirth simulations, to discuss available methods for clinical evaluation of female pelvic floor function, and to review the variation in pelvic floor changes after vaginal childbirth. A high‐resolution magnetic resonance (MR) data set from an asymptomatic nullipara was used to illustrate the MR anatomy of the female pelvic floor. Manual segmentation was performed and three‐dimensional reconstructions of the pelvic floor structures were generated, which were used to illustrate the 3D anatomy of the pelvic floor. Variation in the post partum appearance of the levator ani muscles is illustrated using other 2D MR data sets, which depict unilateral and bilateral disruptions in the puborectalis portion of levator ani, as well as shape variations, which may be seen in the post partum levator. The clinical evaluation of the pelvic floor is then reviewed. The female pelvis is composed of a bony scaffold, from which the pelvic floor muscles (obturator internus, levator ani) are suspended. The rectum fits in a midline groove in the levator ani. The vagina is suspended across the midline, attaching bilaterally to the obturator and levator ani. The vagina supports the bladder and urethra. MR studies have demonstrated disruptions in levator ani attachments after vaginal childbirth. Such disruptions are rare in women who have not given birth vaginally. Changes to the neuromuscular apparatus of the pelvic floor can also be demonstrated after vaginal delivery. The combination of childbirth‐related anatomic and neurological injury to the pelvic floor may be associated with pelvic floor dysfunction (PFD). These changes are difficult to study in vivo but may be studied through simulations. Appropriate consideration of clinical anatomy is important in these simulations.

Cost analysis of open versus robotic-assisted sacrocolpopexy.

Objective This study aimed to report on the costs, operative times, and length of stay for robotic and open sacrocolpopexy. Study Design This retrospective study compares consecutive open and robotic sacrocolpopexies that were performed beyond the surgical learning curve. Hospital direct costs, operative times, and length of stay were compared for the 2 groups. Robot cost and maintenance were included. Statistical significance was considered at P < 0.05. Results The study comprised 91 open and 73 robotic sacrocolpopexies. Both groups were similar clinically. Median operative times for open and robotic approaches were 166 and 212 minutes (P < 0.001), respectively, and length of stay was 3 versus 2 days (P < 0.001). Of the women in the robotic group, 48% had length of stay less than 24 hours versus 1% in the open group. Median robotic and open procedure direct costs were

A reliable, valid instrument to assess patient knowledge about urinary incontinence and pelvic organ prolapse

6668 and

A logarithmic opinion pool based STAPLE algorithm for the fusion of segmentations with associated reliability weights.

7804 (P = 0.002), respectively. Readmission rates at 30 days postoperatively were similar. Conclusions Robotic sacrocolpopexy costs less but takes slightly longer to perform than the open procedure.

Measurements from image-based three dimensional pelvic floor reconstruction: a study of inter- and intraobserver reliability.

The objective of this study is to develop a reliable, validated questionnaire to assess patient knowledge about urinary incontinence (UI) and pelvic organ prolapse (POP). We designed a written questionnaire comprised of UI and POP scales and administered it to 133 gynecologic and 61 urogynecologic patients. We performed a principal components factor analysis for UI and POP items and assessed construct validity, internal consistency, and stability of each scale. For both scales, mean total urogynecologic group scores exceeded those for gynecologic patients (P values < 0.001), suggesting construct validity. Both scales had excellent internal consistency (Cronbach’s alpha > 0.8). Mean test scores were slightly higher upon retest (UI, 0.46, P = 0.046; POP, 0.33, P = 0.126). Pearson’s correlation between initial and repeat scores was high for UI (0.675) and POP scales (0.940), indicating questionnaire stability. We developed a reliable, valid instrument for assessing patient knowledge about UI and POP.

Do racial differences in knowledge about urogynecologic issues exist

Pelvic floor dysfunction is common in women after childbirth and precise segmentation of magnetic resonance images (MRI) of the pelvic floor may facilitate diagnosis and treatment of patients. However, because of the complexity of its structures, manual segmentation of the pelvic floor is challenging and suffers from high inter and intra-rater variability of expert raters. Multiple template fusion algorithms are promising segmentation techniques for these types of applications, but they have been limited by imperfections in the alignment of templates to the target, and by template segmentation errors. A number of algorithms sought to improve segmentation performance by combining image intensities and template labels as two independent sources of information, carrying out fusion through local intensity weighted voting schemes. This class of approach is a form of linear opinion pooling, and achieves unsatisfactory performance for this application. We hypothesized that better decision fusion could be achieved by assessing the contribution of each template in comparison to a reference standard segmentation of the target image and developed a novel segmentation algorithm to enable automatic segmentation of MRI of the female pelvic floor. The algorithm achieves high performance by estimating and compensating for both imperfect registration of the templates to the target image and template segmentation inaccuracies. A local image similarity measure is used to infer a local reliability weight, which contributes to the fusion through a novel logarithmic opinion pooling. We evaluated our new algorithm in comparison to nine state-of-the-art segmentation methods and demonstrated our algorithm achieves the highest performance.

Surgery for stress urinary incontinence in the United States: does race play a role?

To describe inter‐ and intraobserver reliability of 3D measurements of female pelvic floor structures.