Leon Ginzburg

Adenocarcinoma occurring in regional jejunitis

Abstract Two cases of regional jejunitis are reported in which a primary adenocarcinoma developed at the site of a stenosing jejunitis in the proximal jejunum. It is suggested that adenocarcinoma may be a complication of granulomatous jejunitis.

Ileocolostomy with exclusion for non-specific ileitis

1. A series of 40 cases of regional ileitis treated by ileo-colostomy with exclusion is reported. 2. There were no operative mortalities nor any serious post-operative complications. 3. 40 cases were available for follow-up studies. There was recession of disease in the excluded loop in 35. 4. The above five failures include two cases complicated by a large ileo-sigmoidal fistula. In this type of case the operation is ineffective and cannot be expected to offer satisfactory results. If this type of case be excluded, the ratio of unsuccessful cases is 3 out of 38. 5. Appearance of disease in proximal segments previously uninvolved occurred in 1 case. 6. Proximal extension of the disease appears to be independent of the type of operation used to treat the primary lesion. 7. The important factor in preventing such extension appears to be to carry the site of exclusion or resection sufficiently orad.