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Dive into the research topics where Leslie L. Nicholson is active.

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Featured researches published by Leslie L. Nicholson.


Spine | 2004

Cervical range of motion associations with subclinical neck pain.

Haejung Lee; Leslie L. Nicholson; Roger Adams

Study Design. Cross-sectional study. Objective. To investigate associations between subclinical neck pain/discomfort, and range of motion and physical dimensions of the cervicothoracic spine. Summary of Background Data. Despite the high prevalence of neck problems, few studies are available indicating any physical associations with the development of neck pain, or information regarding early signs of pathology from neck pain for subjects not in treatment. Methods. Forty healthy volunteers, between 19 and 42 years of age (mean age 28 years), were recruited. The dimensions of the cervicothoracic spine measured were as follows: spinal posture, active cervical range of motion, and segment length of the neck. All measurements were taken twice from each subject by different testers, on the same occasion. Cervical muscle endurance was measured by a modified Biering-Sørensen Test. Finally, subjects were questioned about any recurrent neck pain/discomfort. Results. Fourteen subjects reported experiencing low-level neck pain/discomfort on a recurrent basis. Neck muscle endurance time (F1,38 = 6.75, P = 0.01) and left rotation end-of-range (F1,38 = 4.56, P = 0.04) were found to be significantly lower for subjects with neck pain. Extension end-of-range showed a group-specific change at retest, increasing for subjects without pain, but decreasing for those with neck pain (F1,38 = 4.67, P = 0.04). This same group had a greater range of retraction than the asymptomatic group (F1,38 = 4.56, P = 0.04). Subjects overall, irrespective of pain classification, demonstrated greater left rotation than right rotation (F1,38 = 4.34, P = 0.04) and also showed reduced side flexion on the left (F1,38 = 5.10, P = 0.03) and right (F1,38 = 5.27, P = 0.03) with repeated measurement. Conclusions. Between-groups differences were observed as lower neck muscle endurance time, reduced left rotation, relatively reduced extension at second test, but greater range of retraction, when the subclinical and normal groups were compared. These data suggest that there are early range changes associated with the development of neck pain.


Spine | 2006

Development and psychometric testing of Korean language versions of 4 neck pain and disability questionnaires

Haejung Lee; Leslie L. Nicholson; Roger Adams; Christopher G. Maher; Mark Halaki; Sung-Soo Bae

Study Design. Cohort study. Objectives. To develop and establish the psychometric properties of Korean versions of 4 neck pain and disability questionnaires: the Neck Disability Index, Neck Pain and Disability Scale, Functional Rating Index, and Short Form McGill Pain Questionnaire (SFMPQ). Summary of Background Data. To our knowledge, there are no published Korean language neck pain and disability measures. Methods. Versions of each questionnaire in idiomatic modern Korean were developed with a process involving initial independent translation, synthesis of the translations, independent back translation, and review by an expert committee to achieve equivalence with the original English. Psychometric testing of the questionnaires with 261 subjects was undertaken to examine test-retest reliability, internal consistency, discriminative validity, and longitudinal construct validity. Results. Test-retest reliability of the translated versions of the 3 disability questionnaires was excellent (intraclass correlation coefficient[2,1] = 0.86–0.90). High internal consistency was found in the 3 disability questionnaires (Cronbach-α ranged from α = 0.88 for the Functional Rating Index to α = 0.96 for the Neck Pain and Disability Scale, and 0.82 for the SFMPQ). The visual analog scale subscale of the SFMPQ was the most responsive of the subscales (effect size = 1.44, standardized response mean = 1.37). The visual analog scale was also the most responsive pain and disability index in internal responsiveness analysis, although disability indexes showed marginally better responsiveness when compared with external standards. No floor or ceiling effects were observed. Conclusions. We conclude that the questionnaires were successfully translated and show acceptable measurement properties, and, as such, are suitable for use in clinical and research applications.


American Journal of Sports Medicine | 2010

Generalized Joint Hypermobility and Risk of Lower Limb Joint Injury During Sport A Systematic Review With Meta-Analysis

Verity Pacey; Leslie L. Nicholson; Roger Adams; Joanne Munn; Craig Munns

Background: Generalized joint hypermobility is a highly prevalent condition commonly associated with joint injuries. The current literature has conflicting reports of the risk of joint injury in hypermobile sporting participants compared with their nonhypermobile peers. Systematic reviews have not been conclusive and no meta-analysis has been performed. Purpose: This review was undertaken to determine whether individuals with generalized joint hypermobility have an increased risk of lower limb joint injury when undertaking sporting activities. Study Design: Systematic review with meta-analysis. Methods: Studies were identified through a search without language restrictions of PubMed, CINAHL, Embase, and SportDiscus databases from the earliest date through February 2009 with subsequent handsearching of reference lists. Inclusion criteria for studies were determined before searching and all included studies underwent methodological quality assessment by 2 independent reviewers. Meta-analyses for joint injury of the lower limb, knee, and ankle were performed using a random effects model. The difference in injury proportions between hypermobility categories was tested with the z statistic. Results: Of 4841 identified studies, 18 met all inclusion criteria with methodological quality ranging from 1 of 6 to 5 of 6. A variety of tests of hypermobility and varied cutoff points to define the presence of generalized joint hypermobility were used, so the authors determined a standardized cutoff to indicate generalized joint hypermobility. Using this criterion, a significantly increased risk of knee joint injury for hypermobile and extremely hypermobile participants compared with their nonhypermobile peers was demonstrated (P < .001), whereas no increased risk was found for ankle joint injury. For knee joint injury, a combined odds ratio of 4.69 (95% confidence interval, 1.33-16.52; P = .02) was calculated, indicating a significantly increased risk for hypermobile participants playing contact sports. Conclusion: Sport participants with generalized joint hypermobility have an increased risk of knee joint injury during contact activities but have no altered risk of ankle joint injury.


American Journal of Sports Medicine | 2010

Generalized Joint Hypermobility and Risk of Lower Limb Joint Injury During Sport

Verity Pacey; Leslie L. Nicholson; Roger Adams; Joanne Munn; Craig Munns

Background: Generalized joint hypermobility is a highly prevalent condition commonly associated with joint injuries. The current literature has conflicting reports of the risk of joint injury in hypermobile sporting participants compared with their nonhypermobile peers. Systematic reviews have not been conclusive and no meta-analysis has been performed. Purpose: This review was undertaken to determine whether individuals with generalized joint hypermobility have an increased risk of lower limb joint injury when undertaking sporting activities. Study Design: Systematic review with meta-analysis. Methods: Studies were identified through a search without language restrictions of PubMed, CINAHL, Embase, and SportDiscus databases from the earliest date through February 2009 with subsequent handsearching of reference lists. Inclusion criteria for studies were determined before searching and all included studies underwent methodological quality assessment by 2 independent reviewers. Meta-analyses for joint injury of the lower limb, knee, and ankle were performed using a random effects model. The difference in injury proportions between hypermobility categories was tested with the z statistic. Results: Of 4841 identified studies, 18 met all inclusion criteria with methodological quality ranging from 1 of 6 to 5 of 6. A variety of tests of hypermobility and varied cutoff points to define the presence of generalized joint hypermobility were used, so the authors determined a standardized cutoff to indicate generalized joint hypermobility. Using this criterion, a significantly increased risk of knee joint injury for hypermobile and extremely hypermobile participants compared with their nonhypermobile peers was demonstrated (P < .001), whereas no increased risk was found for ankle joint injury. For knee joint injury, a combined odds ratio of 4.69 (95% confidence interval, 1.33-16.52; P = .02) was calculated, indicating a significantly increased risk for hypermobile participants playing contact sports. Conclusion: Sport participants with generalized joint hypermobility have an increased risk of knee joint injury during contact activities but have no altered risk of ankle joint injury.


Sports Medicine | 2007

Prognosis of conservatively managed anterior cruciate ligament injury: a systematic review.

Qassim I. Muaidi; Leslie L. Nicholson; Kathryn M. Refshauge; Robert D. Herbert; Christopher G. Maher

Anterior cruciate ligament (ACL) rupture is a common sporting injury, often managed surgically with patella-tendon or hamstrings-gracilis autograft. Some people who sustain the injury, request information about their prognosis if they choose to forgo surgery and opt for conservative management. Numerous studies provide data on the prognosis of conservatively managed ACL injuries. These studies have not been systematically reviewed. Thus, the aims of this systematic review are to describe the natural history and clinical course of function and proprioception in the conservatively managed ACL-deficient knee, and to identify prognostic factors. We searched MEDLINE, CINAHL, EMBASE, SportDiscus, PEDro and the Cochrane Central Register of Clinical Trials without language restrictions from the earliest record available up to July 2006. We also searched the Science Citation Index, and iteratively searched bibliographies for prospective studies of outcomes (>6 months follow-up) of conservatively managed complete ACL tears. Six criteria were used to assess the methodological quality of included studies. The main outcome measures were self-reported measures of knee function, activity level, performance in functional tasks and knee proprioception. Fifteen studies of variable methodological quality were included in the review. On average, patients with mixed or isolated ACL-deficient knees reported good knee function (87/100 Lysholm knee scale) at follow-up duration of 12–66 months. On average, functional performance assessed with the hop-for-distance test, was in the normal range. From pre-injury to follow-up there was a reduction in Tegner activity level of 21.3%. According to the methods used in the assessed studies, conservatively managed ACL-deficient knees have a good short-to mid-term prognosis in terms of self-reported knee function and functional performance. However, subjects reduced their activity levels on average by 21% following injury.


Physical Therapy | 2010

Effects of Mastectomy on Shoulder and Spinal Kinematics During Bilateral Upper-Limb Movement

Jack Crosbie; Sharon L. Kilbreath; Elizabeth Dylke; Kathryn M. Refshauge; Leslie L. Nicholson; Jane Beith; Andrew J. Spillane; Kate White

Background Shoulder movement impairment is a commonly reported consequence of surgery for breast cancer. Objective The aim of this study was to determine whether shoulder girdle kinematics, including those of the scapula, spine, and upper limb, in women who have undergone a unilateral mastectomy for breast cancer are different from those demonstrated by an age-matched control group. Design An observational study using 3-dimensional kinematic analysis was performed. Methods Women who had a unilateral mastectomy on their dominant-arm side (n=29, mean [±SD] age=62.4±8.9 years) or nondominant-arm side (n=24, mean [±SD] age=59.8±9.9 years), as well as a control group of age-matched women without upper-limb, shoulder, or spinal problems (n=22, mean [±SD] age=58.1±11.5 years), were measured while performing bilateral arm movements in the sagittal, scapular, and coronal planes. All of the women were free of shoulder pain at the time of testing. Data were collected from the glenohumeral joint, the scapulothoracic articulation, and the spine (upper and lower thoracic and lumbar regions) using an electromagnetic tracking system. Results Women following mastectomy displayed altered patterns of scapular rotation compared with controls in all planes of movement. In particular, the scapula on the mastectomy side rotated upward to a markedly greater extent than that on the nonmastectomy side, and women following mastectomy displayed greater scapular excursion than controls. Conclusions The findings suggest that altered motor patterns of the scapula are associated with mastectomy on the same side. Whether these changes are harmful or not is unclear. Investigation of interventions designed to restore normal scapulohumeral relationships on the affected side following unilateral mastectomy for breast cancer is warranted.


Journal of Orthopaedic & Sports Physical Therapy | 2009

Sports Participation and Humeral Torsion

Rod Whiteley; Karen A. Ginn; Leslie L. Nicholson; Roger Adams

STUDY DESIGN Cross-sectional study. OBJECTIVE To examine differences between arms in humeral torsion in adult and adolescent throwing and nonthrowing athletes, and nonathletic adults. BACKGROUND It is hypothesized that humeral retrotorsion develops by, and is beneficial for, throwing. Thus throwers should demonstrate greater retrotorsion in their dominant arm relative to their nondominant arm and have more side-to-side retrotorsion difference than nonthrowing groups. In addition, adult throwers should have a greater side-to-side retrotorsion difference than adolescent throwers, and swimmers should not demonstrate a retrotorsion difference. METHODS AND MEASURES Using ultrasound to standardize the location of the bicipital groove, the amount of humeral torsion was measured in both arms of male baseball players (85 adult, 35 adolescent), female softball players (16 adult, 37 adolescent), 29 elite adolescent swimmers (19 female), and 16 nonathletic adults (8 female). RESULTS More retrotorsion was found in the dominant arm of almost all throwing athletes, irrespective of their gender or whether they were adults or adolescents (mean+/-SD side-to-side difference, 11.9 degrees+/-10.5 degrees). This difference was less for swimmers (6.4 degrees+/-9.9 degrees) and nonathletic adults (1.3 degrees+/-8.9 degrees). CONCLUSION Greater dominant armhumeral retrotorsion is observed contingent with participation in throwing sports.


Scandinavian Journal of Medicine & Science in Sports | 2008

Do elite athletes exhibit enhanced proprioceptive acuity, range and strength of knee rotation compared with non‐athletes?

Qassim I. Muaidi; Leslie L. Nicholson; Kathryn M. Refshauge

The aims of this study were to compare proprioception in knee rotation in Olympic‐level soccer players (N=18) with non‐athletes (N=18), to explore between‐limb differences in soccer players, and examine correlations between proprioception and years of playing, function, physical measures and skill level. The knee rotatory kinaesthetic device was used to present stimuli of different magnitudes to determine proprioceptive acuity for internal and external active rotation, and to measure active and passive rotation range of motion (ROM). Knee rotation strength was measured using a dynamometer. Proprioceptive acuity of the athletes was significantly (P=0.004) better than that of the non‐athletes. Athletes displayed significantly less passive ROM (P=0.001), higher isometric muscle strength (P=0.006) and greater hop for distance (P=0.001) than non‐athletes. No significant between‐limb differences were found in the athletes in any objective outcome measure. Internal rotation proprioceptive acuity was negatively correlated with coach‐rated ball skill (r=−0.52) and positively correlated with internal rotation ROM (r=0.59). Our findings suggest that highly trained athletes possess enhanced proprioceptive acuity and muscle strength that may be inherent, or may develop as a result of long‐term athletic training.


Journal of Science and Medicine in Sport | 2010

Reduced humeral torsion predicts throwing-related injury in adolescent baseballers

Rod Whiteley; Richard Douglas Adams; Leslie L. Nicholson; Karen A. Ginn

The amount of torsion in the humerus is determined by both genetic and activity-related factors, and affects the external rotation range of motion available at the shoulder. Previous research has shown athletes participating in throwing sports to have a greater amount of humeral retrotorsion in their dominant arm. The purpose of this study was to investigate the predictive ability of both the genetic and activity-related aspects of humeral torsion regarding throwing-related injury. The amount of humeral torsion in both arms of 35 high level adolescent male baseballers (mean age 16.6 years+/-0.6 years) was measured at study commencement. Significantly increased humeral retrotorsion in the dominant arm compared to the non-dominant arm was found (p=0.04). These athletes were followed for a period of 30 months, and any injury to their throwing arm which resulted in missing either a game or practice was recorded. ROC curve analysis was used to determine the predictive ability of humeral torsion with respect to the occurrence of injury to the throwing arm. Of the 35 athletes, 19 suffered a throwing arm injury. AUC values derived from ROC analysis showed humeral torsion in the non-dominant arm (AUC: 0.679, 95% CI: 0.502-0.857), as well as the average of the humeral torsion in both arms (0.692, 0.512-0.873), to be predictive of injury. Torsion in the dominant arm was not a significant throwing arm injury predictor. Thus non-dominant arm humeral torsion (the genetic contribution) was found to be the predictor of throwing arm injury.


Journal of Science and Medicine in Sport | 2012

The effect of ankle taping or bracing on proprioception in functional ankle instability: A systematic review and meta-analysis

Jacqueline Raymond; Leslie L. Nicholson; Claire E. Hiller; Kathryn M. Refshauge

OBJECTIVES To determine if wearing an ankle brace or taping the ankle, compared to no brace or tape, improves proprioceptive acuity in people with a history of ankle sprain or functional ankle instability. DESIGN Systematic review and meta-analysis. METHODS Studies using controlled, cross-over designs whereby participants who had sprained their ankle at least once or had functional ankle instability, underwent some form of proprioceptive sensation testing with and without ankle brace or tape, were included. Proprioceptive acuity was reported for the ankle tape/brace condition and the condition where no tape or brace was worn. Meta-analysis was employed to compare proprioceptive acuity with and without ankle tape/brace. RESULTS Eight studies were included in the review. Studies measured either sense of movement or sense of joint position. The mean differences in 19 of 32 comparisons were not significant. Of the remaining mean differences, 10 were positive, indicating better proprioceptive acuity in the taped/braced condition and 3 were negative, indicating poorer proprioceptive acuity. Overall, there was no significant effect with ankle tape/brace compared to the no tape/brace condition (mean difference: 0.08°, 95% CI: -0.39 to 0.55). This finding was consistent when the two aspects of proprioception (sense of movement or joint position) were considered separately. CONCLUSIONS The pooled evidence suggests that using an ankle brace or ankle tape has no effect on proprioceptive acuity in participants with recurrent ankle sprain or who have functional ankle instability.

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Verity Pacey

Children's Hospital at Westmead

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Craig Munns

Children's Hospital at Westmead

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Louise Tofts

Children's Hospital at Westmead

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