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Li Gm

XinHua Hospital

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Publication

Featured researches published by Li Gm.

Journal of Gene Medicine | 2006

Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats

Li Gm; Qing Xie; Yi Shi; Dingguo Li; Mingjun Zhang; Shan Jiang; Huijuan Zhou; Hanming Lu; Youxin Jin

Connective tissue growth factor (CTGF) is a highly profibrogenic molecule implicated in hepatic fibrogenesis. Small interfering RNA (siRNA) is an effective tool to silence gene expression post‐transcriptionally. Therefore, we conducted an investigation to determine if intraportal vein siRNA injection targeting CTGF inhibits CTGF expression on rat liver in vivo and furthermore whether it protects the liver from liver fibrosis.

Chinese journal of hepatology | 2008

Effect of silencing connective tissue growth factor on rat liver fibrosis and the accumulation of extracellular matrix

Li Gm; Li Dg; Xie Q; Shi Y; Jiang S; Zhou Hj; Lu Hm; Jin Yx

Chinese journal of hepatology | 2010

Effect of silencing connective tissue growth factor on the liver fibrosis in rats

Li Gm; Li Dg; Fan Jg; Xie Q

Chinese journal of hepatology | 2004

Effect of small interfering RNA targeting connective tissue growth factor on the synthesis and secretion of extracellular matrix in hepatic stellate cells

Li Gm; Shi Y; Li Dg; Xie Q; Guo Q; Jin Yx

Chinese journal of hepatology | 2005

[Inhibition of mouse hepatocyte apoptosis by anti-caspase-12 small interfering RNA].

Liu Hf; Xie Q; Jiang S; Li Gm; Zhou Xq; Shi Y; Yu H; Jin Yx

Chinese journal of hepatology | 2003

[Effect of Tauroursodeoxycholic acid on cytochrome C-mediated apoptosis in HepG2 cells].

Xie Q; Li Gm; Zhou Xq; Liao D; Yu H; Guo Q

International Journal of Molecular Medicine | 1998

Ribozyme-mediated inhibition of caspase-12 activity reduces apoptosis induced by endoplasmic reticulum stress in primary mouse hepatocytes

Shan Jiang; Qing Xie; Huijuan Zhou; Wei Zhang; Xia-Qiu Zhou; Li Gm; Yi Shi; Youxin Jin

Chinese journal of hepatology | 2008

[Effects of silencing connective tissue growth factor on rat transforming growth factor beta/Smads signal].

Li Gm; Li Dg; Xie Q; Zong Ch; Jiang S; Lu Hm

Chinese journal of hepatology | 2006

Effect of small interfering RNA targeting connective tissue growth factor on the proliferation of rat primary hepatic stellate cells

Li Gm; Xie Q; Li Dg; Jiang S; Liu Hf; Xu Qf; Jin Yx

Chinese journal of hepatology | 2005

[Caspase-12 expression and activation in the pathogenesis of acute hepatic failure induced by lipopolysaccharide and D-galactosamine].

Zhou Hj; Xie Q; Jiang S; Li Gm; Zhou Xq; Liu Hf; Yu H; Guo Q

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Qing Xie

Shanghai Jiao Tong University

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Huijuan Zhou

Ruijin Hospital

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Shan Jiang

Ruijin Hospital

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Yi Shi

Laboratory of Molecular Biology

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Youxin Jin

Laboratory of Molecular Biology

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Dingguo Li

XinHua Hospital

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Hanming Lu

XinHua Hospital

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Hong Yu

Ruijin Hospital

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Mingjun Zhang

Ruijin Hospital

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