Li-He Yin

(9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth-oxy-17-methyl-morphinan-6-one.

The title compound, C20H25NO4, was synthesized by a Mitsunobu reaction of sinomenine [(9S,13R,14R)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one] with methanol. The chiral centers were unchanged during the reaction. Intramolecular C—H⋯O hydrogen bonds result in the formation of six-membered rings.

2-(2,4-Dichloro­phen­yl)-3-[5-(4-methoxy­phen­yl)-1,3,4-thia­diazol-2-yl]-1,3-thia­zolidin-4-one

In the molecule of the title compound, C18H13Cl2N3O2S2, the thiazolidinone ring has an envelope conformation with the S atom displaced by 0.394 (3) Å from the plane of the other ring atoms. The thiadiazole ring is oriented at a dihedral angle of 7.40 (4)° with respect to the 4-methoxyphenyl ring. Intramolecular C—H⋯S, C—H⋯N and C—H⋯Cl hydrogen bonds result in the formation of two planar and two non-planar five-membered rings. The planar five-membered rings are oriented at a dihedral angle of 6.23 (3)°. The 2,4-dichlorophenyl ring is oriented at dihedral angles of 84.21 (4) and 83.55 (3)° with respect to the thiadiazole and 4-methoxyphenyl rings, respectively. In the crystal structure, intermolecular C—H⋯O hydrogen bonds link the molecules into centrosymmetric dimers.

Diethyl {(4-methoxy-phen-yl)[5-(4-nitro-phen-yl)-1,3,4-thia-diazol-2-ylamino]meth-yl}phospho-nate.

The title compound, C20H23N4O6PS, was synthesized by the reaction of N-(4-methoxybenzylidene)-5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine and diethyl phosphite. The thiadiazole and nitro-substituted phenyl rings in the molecule are approximately coplanar, the dihedral angle being 5.3 (2)°. The dihedral angle formed by the mean plane through all non-H atoms of both the thiadiazole and the nitro-substituted phenyl ring with the plane of the methoxy-substituted phenyl ring is 48.9 (2)°. In the crystal structure, molecules form centrosymmetric dimers as a result of N—H⋯O bonds involving amine H and phosphine oxide O atoms.

2-(2,4-Dichloro-phen-yl)-3-[5-(3,5-dimethyl-phen-yl)-1,3,4-thia-diazol-2-yl]thia-zolidin-4-one.

The title compound, C19H15Cl2N3OS2, was synthesized by the reaction of N-(2,4-dichlorophenyl)-5-(3,5-dimethylphenyl)-1,3,4-thiadiazol-2-amine and mercaptoacetic acid. The thiazolidinone ring adopts a twist conformation. The 2,4-dichlorophenyl ring is almost perpendicular to the thiadiazole ring, the dihedral angle being 82.8 (2)°. The 3,5-dimethylphenyl ring is nearly coplanar with the thiadiazole ring, the dihedral angle being 2.7 (2)°. An intramolecular C—H⋯N hydrogen bond is present.

5-(2-Bromo­phen­yl)-1,3,4-thia­diazol-2-amine

In the title compound, C8H6BrN3S, the thiadiazole ring is oriented at a dihedral angle of 48.35 (3)° with respect to the bromophenyl ring. In the crystal structure, intermolecular N—H⋯N hydrogen bonds link the molecules.

Methyl 2-{[3-(4,6-dimethoxy-pyrimidin-2-yl)ureido]sulfonyl-meth-yl}benzoate.

In the title compound, C16H18N4O7S, a synthetic sulfonylurea herbicide, there are intramolecular N—H⋯N and C—H⋯O hydrogen bonds. Intermolecular N—H⋯O and C—H⋯O hydrogen bonds form centrosymmetric dimers. The dihedral angle between the two rings is 50.00 (15)°.

Diethyl {[5-(2,4-dichloro­phen­yl)-1,3,4-thia­diazol-2-ylamino](4-methoxy­phenyl)methyl}­phospho­nate

The title compound, C20H22Cl2N3O4PS, was synthesized by the reaction of N-(4-methoxybenzylidene)-5-(2,4-dichlorophenyl)-1,3,4-thiadiazol-2-amine and diethyl phosphite. In the crystal, intermolecular C—H⋯O and N—H⋯O hydrogen bonds link the molecules.

N-{(E)-4-[(E)-(Dodecyl-imino)meth-yl]benzyl-idene}dodecan-1-imine.

The title compound, C32H56N2, was synthesized by the reaction of terephthalaldehyde and dodecan-1-amine. The imines adopt trans conformations, with the two halves of the molecule related to each other by a centre of symmetry.

3-[5-(4-Fluoro-phen-yl)-1,3,4-thia-diazol-2-yl]-2-(4-methoxy-phen-yl)-1,3-thia-zolidin-4-one.

The title compound, C18H14FN3O2S2, was synthesized by the reaction of 5-(4-fluorophenyl)-N-(4-methoxybenzylidene)-1,3,4-thiadiazol-2-amine and mercaptoacetic acid. The thiazolidinone ring adopts a twist conformation. The 4-methoxyphenyl ring is almost perpendicular to the thiadiazole ring, making a dihedral angle of 88.4 (3)°. The 4-fluorophenyl ring is nearly coplanar with the thiadiazole ring, the dihedral angle being 6.8 (3)°. The crystal structure involves C—H⋯N, C—H⋯O and C—H⋯S hydrogen bonds.

Dichloridobis(5-m-tolyl-1,3,4-thia­diazol-2-ylamine-κN3)zinc(II)

In the molecule of the title compound, [ZnCl2(C9H9N3S)2], the ZnII atom is four-coordinated by two N atoms from two 5-m-tolyl-1,3,4-thiadiazol-2-ylamine ligands and two Cl anions in a distorted tetrahedral geometry. Intramolecular N—H⋯N, N—H⋯Cl and C—H⋯S hydrogen bonds result in the formation of one planar and one non-planar five-membered, one non-planar six-membered and one non-planar seven-membered ring. The six- and seven-membered rings have twist conformations, while the non-planar five-membered ring adopts an envelope conformation with the S atom displaced by 0.541 (3) Å from the plane of the other ring atoms. The planar five-membered ring is oriented at dihedral angles of 1.74 (3) and 1.08 (3)°, respectively, with respect to the adjacent aromatic and thiadiazole rings. In the crystal structure, intermolecular N—H⋯Cl hydrogen bonds link the molecules into a three-dimensional network.