Li Yuhang

Discussion on the Three Levels of the Prescription-Composition Principle of TCM

This article aims at discussing the various aspects of the Prescription-Composition Principle (zu fang yuan ze) in the Differentiation of Syndrome and Treatment Concept (bian zheng lun zhi) of TCM. With reference to the alleged side effects of Traditional Chinese medicine, the article focuses on the importance of the Differentiation of Syndrome and Treatment Concept for a correct therapy. Accordingly, the three aspects of the Prescription — Composition Principle are introduced: correspondence between syndrome and formula (fang zheng dui ying), correspondence between syndrome and formula factors (fang zheng yao su dui ying), and the differentiation between monarch, minister, assistant and messenger (jun, chen, zuo shi).ZusammenfassungDieser Artikel stellt die verschiedenen Ebenen des Rezepturzusammensetzungsprinzips in der TCM (Zu Fang Yuan Ze) hinsichtlich der Differenzierung von Syndrom und Behandlung (Bian Zheng Lun Zhi) dar. Anhand der Prüfung von Nebenwirkungen der TCM wird geschlossen, dass der Differenzierung von Syndrom und Behandlung mehr Beachtung geschenkt werden sollte. Entsprechend werden die drei Ebenen des Rezepturzusammensetzungsprinzips vorgestellt: Übereinstimmung zwischen Syndrom und Rezeptur (Fang Zheng Dui Ying), Übereinstimmung zwischen Syndrom und Rezepturbestandteilen (Fang Zheng Yao Su Dui Ying), „Monarch, Minister, Assistent und Bote“ (Jun, Chen, Zuo Shi).

Influence of Sanao Tang on urine volume and expression of aquaporin 2 in rats with respiratory function impairment induced by passive smoking and lipopolysaccharide

Abstract OBJECTIVE To investigate the effect of Sanao Tang (SAT) on urine volume and the expression of aquaporin-2 (AQP2) in rats with lung dysfunction induced by passive smoking and lipopolysaccharide. METHODS Totally 45 healthy Specific pathogen Free Wistar Rats were randomized into 3 groups: normal control group, model group and SAT group. A rat model of respiratory dysfunction induced by exposure to cigarette smoking and lipopolysaccharide (LPS). Lavage of decoction of the Chinese medicine was performed for rats in the SAT group. Anires 2005 System was used to analyze the pulmonary function. Urine of rats was collected through metabolism cage method. Enzyme-linked immunosorbent assay (ELISA) was used to determine content of antidiuretic hormone (ADH), angiotensin II (Ang II), atrial natriuretic factor (ANP), endothelin 1 (ET-1), nitric oxide (NO) and prostaglandin E2 (PGE2) in serum, lung and kidney. The expression of AQP2 in rat renal tissue was determined with real-time fluorescence quantitative PCR (RT-PCR). RESULTS (a) In comparison with the normal control, It was found that enforced vital capacity (FVC), 1-second forced expiratory volume/forced vital capacity% (FEV1/FVC%), 24 h urine volume content of NO and PGE2 were decreased, while AQP2mRNA level and content of ADH, Agn II, ANP and ET-1 were increased in the model group with statistical significance ( P P CONCLUSION SAT might effectively regulate the urine volume in the modeled rats; ADH, Ang II, ANP, ET-1, NO and PGE2 might play an important role in the regulation on urine volume by lungs. This might be the mechanisms underpinning the function of lung governing water passage in terms of the theory of Traditional Chinese Medicine.

Sugarcane bagasse dietary fiber as an adjuvant therapy for stable chronic obstructive pulmonary disease: a four-center, randomized, double-blind, placebo-controlled study

Abstract Objective To evaluate the efficacy and safety of sugarcane bagasse dietary fiber as an adjuvant therapy for improving quality of life in patients with stable chronic obstructive pulmonary disease (COPD). Methods This was a multicenter, randomized, double-blind, placebo-controlled trial. A total of 196 participants were randomized into a trial group (treated with 6 g/day sugarcane bagasse plus conventional treatment, n = 98) and a control group (treated with placebo plus conventional treatment, n = 98). All efficacy analyses were performed according to the intention-to-treat (ITT) principle. A per-protocol analysis set (PPS) was used to analyze the cases that completed the clinical trial with good compliance. The trial period was 30 days, with a 6-month follow-up. Pre- and post-treatment pulmonary symptom scores (cough, sputum, wheezing, and dyspnea) were recorded for both groups. The St. Georges Respiratory Questionnaire (SGRQ) and the modified Medical Research Council (mMRC) dyspnea scale were assessed before treatment and at the end of the 6-month follow-up. Results The ITT population was 178 and the PPS population was 166. Post-treatment pulmonary clinical symptoms and severity of dyspnea (mMRC and SGRQ evaluation) were significantly improved in both the trial group and the control group (ITT and PPS: P Conclusion Sugarcane bagasse combined with conventional treatment improved quality of life in patients with stable COPD. Sugarcane bagasse appears to be a safe herbal medicine with potential for treating patients with stable COPD when taken orally as an adjuvant therapy.

Discusión sobre los tres niveles del principio de composición de las recetas de la medicina tradicional china

This article aims at discussing the various aspects of the Prescription-Composition Principle (zu fang yuan ze) in the Differentiation of Syndrome and Treatment Concept (bian zheng lun zhi) of TCM. With reference to the alleged side effects of Traditional Chinese medicine, the article focuses on the importance of the Differentiation of Syndrome and Treatment Concept for a correct therapy. Accordingly, the three aspects of the Prescription - Composition Principle are introduced: correspondence between syndrome and formula (fang zheng dui ying), correspondence between syndrome and formula factors (fang zheng yao su dui ying), and the differentiation between monarch, minister, assistant and messenger (jun, chen, zuo shi).