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Dive into the research topics where Lingao Ruan is active.

Publication


Featured researches published by Lingao Ruan.


Current Microbiology | 2009

Screening of Endophytic Fungi with Antithrombotic Activity and Identification of a Bioactive Metabolite from the Endophytic Fungal Strain CPCC 480097

Bin Wu; Licheng Wu; Lingao Ruan; Mei Ge; Daijie Chen

Fermentation extracts from 1,075 endophytic fungi were screened by the Markwardt method. The endophytic strain CPCC 480097 had the strongest antithrombotic activity and was identified as Fusarium sp. based on morphologic tests and internal transcriptional spacer sequence analysis. The target of the antithrombotic agent from the endophytic strain CPCC 480097 was identified by analysis of the fibrinogen clotting time, amidolytic activity, and fibrinolytic assay. The results showed that this antithrombotic agent is a 28-kDa single-chain fibrinolytic enzyme. The identification of this fibrinolytic enzyme was performed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). The two internal sequences of this enzyme were obtained, and these showed no homology with those of other known fibrinolytic enzymes.


Archive | 2010

New compound and application thereof

Daijie Chen; Minyu Luo; He Huang; Mei Ge; Wei Wei; Lingao Ruan; Sheng Yang; Li Zhu; Weihong Jiang; Xing Xia; Zhijun Yang; Qiushuang Li; Tianjiao Wang; Yu Yin; Tian Yang; Wenxiang Jin


Archive | 2008

Method for processing vancomycin fermentation waste slag with liquid state fermentation

Daijie Chen; Yiping Jin; Mei Ge; Minyu Luo; Jianbin Zhang; Lingao Ruan; Weidong Ye; Yaming Wu; Lijun Ruan; Mingli Zuo


Archive | 2012

Application of 3-amino-2-hydroxy-4-phenyl-valyl-isoleucine

Min Rao; Minyu Luo; Lijun Ruan; Li Zhu; Lingao Ruan; Xing Xia; Mei Ge; Qiushuang Li; Tian Yang


Archive | 2012

3-amino-2-hydroxy-4-phenyl-valyl-isoleucine and preparation method and application thereof

Mei Ge; Qiushuang Li; Xing Xia; Minyu Luo; Hanyan Jiang; Lijun Ruan; Lingao Ruan; Huaixia Kang; Tian Yang; Tianjiao Wang; Min Rao


Archive | 2018

GLYCOPEPTIDE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Chang Shao; 邵昌; Lingao Ruan; 阮林高; Wei Wei; 魏维; Mei Ge; 戈梅; Xing Xia; 夏兴; Qingqian Meng; 孟庆前; Yun Zhang; 张芸; Min Rao; 饶敏


Archive | 2012

Nonenolactone compound, and its preparation and application

Zhijun Yang; Minyu Luo; Xiuping Qian; Weidong Ye; Yiping Jin; Lixia Bao; Wenxiang Jin; Tianjiao Wang; Huaixia Kang; Lingao Ruan; Zhiliang Pan; Daijie Chen; Mei Ge


Archive | 2010

Method for producing norvancomycin

Daijie Chen; Mei Ge; He Huang; Weihong Jiang; Wenxiang Jin; Hang Li; Minyu Luo; Xiaodan Qi; Lingao Ruan; Tianjiao Wang; Wei Wei; Xing Xia; Sheng Yang; Zhijun Yang; Yu Yin; Li Zhu


Archive | 2010

Method for preparing methyl vancomycin

Daijie Chen; Mei Ge; He Huang; Weihong Jiang; Hang Li; Minyu Luo; Xiaodan Qi; Lingao Ruan; Tianjiao Wang; Wei Wei; Xing Xia; Sheng Yang; Tian Yang; Zhijun Yang; Yu Yin; Li Zhu


Archive | 2010

Method for producing chlorine-free vancomycin

Daijie Chen; Mei Ge; He Huang; Weihong Jiang; Wenxiang Jin; Hang Li; Minyu Luo; Lingao Ruan; Tianjiao Wang; Wei Wei; Xing Xia; Sheng Yang; Tian Yang; Zhijun Yang; Yu Yin; Li Zhu

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Daijie Chen

East China University of Science and Technology

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Minyu Luo

Shanghai Jiao Tong University

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Li Zhu

Shanghai Jiao Tong University

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He Huang

Chinese Academy of Sciences

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Sheng Yang

Chinese Academy of Sciences

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Wei Wei

Chinese Academy of Sciences

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Weihong Jiang

Chinese Academy of Sciences

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Zhijun Yang

Shanghai Jiao Tong University

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Tian Yang

Shanghai Jiao Tong University

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Qiushuang Li

Shanghai Jiao Tong University

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