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Dive into the research topics where Lingling Zhang is active.

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Featured researches published by Lingling Zhang.


F1000Research | 2018

Role of B-cell receptors for B-cell development and antigen-induced differentiation

Juan Carlos Yam-Puc; Lingling Zhang; Yang Zhang; Kai-Michael Toellner

B-cell development is characterized by a number of tightly regulated selection processes. Signals through the B-cell receptor (BCR) guide and are required for B-cell maturation, survival, and fate decision. Here, we review the role of the BCR during B-cell development, leading to the emergence of B1, marginal zone, and peripheral follicular B cells. Furthermore, we discuss BCR-derived signals on activated B cells that lead to germinal center and plasma cell differentiation.


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for IgD attenuates the IgM-induced anergy response in transitional and mature B cells.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for Complex antigens drive permissive clonal selection in germinal centers.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for Relation of intra-splenic migration of marginal zone B cells to antigen localization on follicular dendritic cells.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang


F1000 - Post-publication peer review of the biomedical literature | 2018

Faculty of 1000 evaluation for Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

Kai-Michael Toellner; Yang Zhang; Lingling Zhang

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Yang Zhang

University of Birmingham

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