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Dive into the research topics where Lisa E. Sohn is active.

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Featured researches published by Lisa E. Sohn.


Pediatric Anesthesia | 2009

The new air-Q™ intubating laryngeal airway for tracheal intubation in children with anticipated difficult airway: comment

Narasimhan Jagannathan; Andrew G. Roth; Lisa E. Sohn; Thomas Y. Pak; Sapan Amin; Santhanam Suresh

1 Danon MJ, Oh SJ, DiMauro S et al. Lysosomal glycogen storage disease with normal acid maltase. Neurology 1981; 31: 51–57. 2 Maron BJ, Roberts WC, Arad M et al. Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA 2009; 301(12): 1253–1259. 3 Mittnacht AJC, Moung C, Lai WW. Massive cardiac hypertrophy in a patient with Danon disease: an intraoperative transesophageal echocardiographic evaluation. Anesth Analg 2007; 105(4): 963–965. 4 Nishino I, Fu J, Tanji K et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature 2000; 406: 906–910. 5 Dworzak F, Casazza F, Mora M et al. Lysosomal glycogen storage with normal acid maltase: a familial study with successful heart transplant. Neuromuscul Disord 1994; 4(3): 243–247. 6 Arad M, Maron BJ, Gorham JM et al. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. N Engl J Med 2005; 352(4): 362–372. 7 Charron P, Villard E, Sebillon P et al. Danon’s disease as a cause of hypertrophic cardiomyopathy: a systematic survey. Heart 2004; 90: 842–846. 8 Yang Z, McMahon CJ, Smith LR et al. Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children. Circulation 2005; 112: 1612–1617. 9 Sugie K, Yamamoto A, Murayama K et al. Clinicopathological features of genetically confirmed Danon disease. Neurology 2002; 58: 1773–1778. 10 Balmer C, Ballhausen C, Bosshard NU et al. Familial X-linked cardiomyopathy (Danon disease): diagnostic confirmation by mutation analysis of the LAMP2 gene. Eur J Pediatr 2005; 164: 509–514. 11 Prall FR, Drack A, Taylor M et al. Opthalmic manifestations of Danon disease. Ophthalmology 2006; 113: 1010–1013. 12 Lake CL, Booker PB. Pediatric Cardiac Anesthesia, 4th edn. Philadelphia: Lippincott Williams & Wilkins, 2005: 532–534.


Pediatric Anesthesia | 2009

The new air-QTM intubating laryngeal airway for tracheal intubation in children with anticipated difficult airway: a case series: THE NEW AIR-QTM INTUBATING LARYNGEAL AIRWAY FOR ANTICIPATED DIFFICULT AIRWAY IN CHILDREN

Narasimhan Jagannathan; Andrew G. Roth; Lisa E. Sohn; Thomas Y. Pak; Sapan Amin; Santhanam Suresh

The air‐Q intubating laryngeal airway (ILA) is a new supraglottic airway device which may overcome some limitations inherent to the classic laryngeal mask airway for tracheal intubation. We present a case series of patients with anticipated difficult airway in whom the air‐Q ILA was successfully used as a conduit for fiberoptic intubation.


Anesthesia & Analgesia | 2011

A clinical evaluation of the intubating laryngeal airway as a conduit for tracheal intubation in children.

Narasimhan Jagannathan; Ryan J. Kozlowski; Lisa E. Sohn; Kenneth E. Langen; Andrew G. Roth; Isabella Mukherji; Melanie F. Kho; Santhanam Suresh

BACKGROUND:The air-Q™ Intubating Laryngeal Airway (ILA) (Cookgas LLC, Mercury Medical, Clearwater, FL) is a supraglottic airway device available in pediatric sizes, with design features to facilitate passage of cuffed tracheal tubes when used to guide tracheal intubation. We designed this prospective observational study of the ILA to assess the ease of its placement in paralyzed pediatric patients, determine its position and alignment to the larynx using a fiberoptic bronchoscope, gauge its efficacy as a conduit for fiberoptic intubation with cuffed tracheal tubes, and evaluate the ability to remove the ILA without dislodgement of the tracheal tube after successful tracheal intubation. METHODS:One hundred healthy children, aged 6 months to 8 years, ASA physical status I to II, and scheduled for elective surgery requiring general endotracheal anesthesia were enrolled in this prospective study. Based on the manufacturers guidelines, each patient received either a size 1.5 or 2.0 ILA according to their weight. The number of attempts for successful insertion, leak pressures, fiberoptic grade of view, number of attempts and time for tracheal intubation, time for ILA removal, and complications were recorded. RESULTS:ILA placement, fiberoptic tracheal intubation, and ILA removal were successful in all patients. The size 1.5 ILA cohort had significantly higher rates of epiglottic downfolding compared with the size 2.0 ILA cohort (P < 0.001), despite adequate ventilation variables. When comparing fiberoptic grade of view to weight, a moderate negative correlation was found (r = −0.41, P < 0.001), indicating that larger patients tended to have better fiberoptic grades of view. The size 1.5 ILA cohort had a significantly longer time to intubation (P = 0.04) compared with the size 2.0 ILA cohort. However, this difference may not be clinically significant because there was a large overlap of confidence bounds in the average times of the size 1.5 ILA (27.0 ± 13.0 seconds) and size 2.0 ILA cohorts (22.7 ± 6.9 seconds). When comparing weight to time to tracheal intubation, a weak correlation that was not statistically significant was found (r = −0.17, P = 0.09), showing that time to intubation did not differ significantly according to weight, despite higher fiberoptic grades in smaller patients. CONCLUSIONS:The ILA was easy to place and provided an effective conduit for tracheal intubation with cuffed tracheal tubes in children with normal airways. Additionally, removal of the ILA after successful intubation could be achieved quickly and without dislodgement of the tracheal tube. Because of the higher incidence of epiglottic downfolding in smaller patients, the use of fiberoptic bronchoscopy is recommended to assist with tracheal intubation through this device.


Pediatric Anesthesia | 2013

A randomized equivalence trial comparing the i-gel and laryngeal mask airway Supreme in children

Narasimhan Jagannathan; Katherine Sommers; Lisa E. Sohn; Amod Sawardekar; Ravi Shah; Isabella Mukherji; Steven Miller; Polina Voronov; Sally Seraphin

The laryngeal mask airway Supreme (Supreme) is a new single‐use supraglottic device with gastric access capability now available in all sizes for children.


Pediatric Anesthesia | 2011

Retrospective audit of the air‐Q intubating laryngeal airway as a conduit for tracheal intubation in pediatric patients with a difficult airway

Narasimhan Jagannathan; Melanie F. Kho; Ryan J. Kozlowski; Lisa E. Sohn; Aisha Siddiqui; David T. Wong

Objectives:  To assess the efficacy of the ILA as a conduit for tracheal intubation in pediatric patients with a difficult airway.


Pediatric Anesthesia | 2009

Unilateral groin surgery in children: will the addition of an ultrasound‐guided ilioinguinal nerve block enhance the duration of analgesia of a single‐shot caudal block?

Narasimhan Jagannathan; Lisa E. Sohn; Amod Sawardekar; Andrew P. Ambrosy; Jennifer A. Hagerty; Anthony C. Chin; Kathleen Barsness; Santhanam Suresh

Background:  Inguinal hernia repair, hydrocelectomy, and orchidopexy are commonly performed surgical procedures in children. Postoperative pain control is usually provided with a single‐shot caudal block. Blockade of the ilioinguinal nerve may lead to additional analgesia. The aim of this double‐blind, randomized controlled trial was to evaluate the efficacy of an adjuvant blockade of the ilioinguinal nerve using ultrasound (US) guidance at the end of the procedure with local anesthetic vs normal saline and to explore the potential for prolongation of analgesia with decreased need for postoperative pain medication.


Pediatric Anesthesia | 2012

A randomized trial comparing the Ambu® Aura-i™ with the air-Q™ intubating laryngeal airway as conduits for tracheal intubation in children

Narasimhan Jagannathan; Lisa E. Sohn; Amod Sawardekar; Jason Gordon; Ravi Shah; Isabella Mukherji; Andrew G. Roth; Santhanam Suresh

To assess the clinical performance of the Ambu Aura‐i (Aura‐i) in children.


BJA: British Journal of Anaesthesia | 2014

Elective use of supraglottic airway devices for primary airway management in children with difficult airways

Narasimhan Jagannathan; L. Sequera-Ramos; Lisa E. Sohn; B. Wallis; A. Shertzer; K. Schaldenbrand

BACKGROUND Supraglottic airways (SGAs) have an established role in airway management of difficult airways in both adults and children. However, there are limited data regarding the use of SGAs for primary airway management in children. The aim of this study is to assess the success rates and adverse events related to the use of SGAs for primary airway management during anaesthesia in children with difficult airways. METHODS A retrospective analysis of SGA use for primary airway management in the difficult airway population in a single centre over a 4-yr period was performed. Difficult airway was defined as either a history of difficult direct laryngoscopy (a documented Cormack and Lehane Grade 3 or greater and the need for an alternate device to direct laryngoscopy for successful tracheal intubation), a history of difficult mask ventilation, or both. The difficult airway condition, patient characteristic data, type and length of procedure, type and size of SGA placed, number of attempts for successful device placement, success/failure associated with the device during anaesthetic maintenance, and complications were recorded. RESULTS A total of 77,272 children received general anaesthesia in a free-standing paediatric institution. Four hundred and fifty-nine patients were reported to have a difficult airway. Of those, 109 received general anaesthesia and an SGA for primary management, meeting the inclusion criteria for this study during a 4-yr period. An SGA was successfully used in 96% of these patients. In four patients, an alternative airway was needed. CONCLUSIONS SGAs can be effectively utilized for airway maintenance in the paediatric difficult airway population.


Anaesthesia | 2012

A randomised comparison of the LMA Supreme™ and LMA ProSeal™ in children

Narasimhan Jagannathan; Lisa E. Sohn; Amod Sawardekar; J. Gordon; K. E. Langen; K. Anderson

We conducted a randomised trial comparing the size‐2 LMA Supreme™ with the LMA ProSeal™ in 60 children undergoing surgery. The outcomes measured were airway leak pressure, ease and time for insertion, fibreoptic examination, incidence of gastric insufflation, ease of gastric tube placement, quality of the airway during anaesthetic maintenance and complications. There were no statistically significant differences between the LMA Supreme and LMA ProSeal in median (IQR [range]) insertion time (12 (10–15 [7–18]) s vs 12 (10–13 [8–25]) s; p = 0.90), airway leak pressures (19 (16–21 [12–30]) cmH2O vs 18 (16–24 [10–34]) cmH2O; p = 0.55), fibreoptic position of the airway or drain tube, ease of gastric access and complications. Both devices provided effective ventilation requiring minimal airway manipulation. The LMA Supreme can be a useful alternative to the LMA ProSeal when single‐use supraglottic devices with gastric access capabilities are required.


Pediatric Anesthesia | 2015

An update on newer pediatric supraglottic airways with recommendations for clinical use

Narasimhan Jagannathan; Melissa Ramsey; Michelle C. White; Lisa E. Sohn

Supraglottic airways are an established part of routine and emergency pediatric airway management, including use in difficult airways and neonatal resuscitation. With the introduction of newer supraglottic airways in children, efficacy can only be determined by comparing these devices with those that are already well established (laryngeal mask airway Classic and laryngeal mask airway ProSeal). This narrative review aims to present the current literature on these newer supraglottic airways and give recommendations for their use in various clinical scenarios based on the existing evidence.

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L. Sequera-Ramos

Children's Memorial Hospital

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Andrea Huang

Children's Memorial Hospital

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Andrew G. Roth

Children's Memorial Hospital

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Ravi Shah

Northwestern University

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