Liu Guozhang

Percutaneous transluminal renal angioplasty in aortoarteritis

Percutaneous transluminal renal angioplasty (PTRA) was performed in 26 patients with aortoarteritis, including unilateral renal artery stenosis in ten patients, bilateral renal artery stenosis in 16 patients. The total of 37 stenotic artery were performed by PTRA. Among them, 30 stenosis (81.1 per cent) were technically successful, three stenosis (8.1 per cent) were technically improved, and four stenosis were resistant to dilatation. The blood pressure responses were observed after PTRA, including cured in 17 patients (65.4 per cent), improved in five patients (19.2 per cent), failed in four patients (15.4 per cent). Sixteen patients after successful angioplasty were followed-up from 6 months to 15 years (average 5.4 years). The blood pressure was still normal in 12 patients (75 per cent). The blood pressure gradually increased may be due to restenosis in four patients (25 per cent).

Polymorphism of angiotensin I converting enzyme gene in the older Chinese: linked to ambulatory blood pressure levels and circadian blood pressure rhythm

Abstract This study was undertaken to evaluate the association of polymorphism of angiotensin I converting enzyme (ACE) gene with casual and ambulatory blood pressure in the Chinese population. Genomic DNA was amplified by polymerase chain reaction (PCR) using primers flanking the polymorphic region in intron 16 of the ACE gene. Alleles were detected on agarose gels stained with ethidium bromide. Casual blood pressure was measured in the 133 normotensive and 122 essential hypertensive subjects; of the essential hypertensive subjects, 65 patients underwent non-invasive ambulatory blood pressure. There was no significant difference of ACE genotype and allele frequencies between the hypertensive and normotensive subjects. Non-significant differences were demonstrated in gender, age, casual blood pressure according to the ACE gene genotypes in the 65 patients who underwent non-invasive ambulatory blood pressure; however, effects of the ACE gene genotypes were observed on the derivatives of ambulatory blood pressure, including sleeping blood pressure levels and circadian blood pressure rhythm ( P

Clinical study of aortic regurgitation in patients with aortoarteritis

Six patients with aortoarteritis complicating aortic regurgitation (14.0%) were found by ascending aorta angiography, seven patients (4. 2%) were found by echocardiography and 30 patients (27.3%) were found by color Doppler echocardiography in our group. Among 43 patients, mild in 21 patients (48.9%), moderate in 17 patients (39.5%) and severe in five patients (11.6%) were determined. Four patients had angina pectories due to myocardial ischemia, but coronary angiography were normal. The aortic valve thickening was found by echocardiography in three patients and aortic valve replacement was performed in two patients in our series.