Lj Goldstein
Johnson & Johnson
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Publication
Featured researches published by Lj Goldstein.
Value in Health | 2014
C.W. Hsiao; D.A. Ondrejicka; Lj Goldstein
PMs14 BuDget iMPact of converting stanDarD treatMent of flail chest froM suPPortive theraPy to surgical fixation With contoureD titaniuM Plates in canaDian hosPitals Hsiao C.W., Ondrejicka D.A., Goldstein L.J. Johnson and Johnson Medical Companies, Markham, ON, Canada Objectives: Flail chest occurs in 6-15% of patients sustaining blunt chest wall trauma and can be life-threatening. It is typically managed through supportive therapies (e.g. ventilation, pain control) but an increasing body of evidence shows decreased patient mortality and morbidity with rib fixation surgery. The objective of our study was to evaluate the budget impact of changing the treatment for flail chest from supportive therapy to surgical management with contoured titanium plates in a Canadian hospital. MethOds: A budget impact model was created using clinical and economic data obtained from peer-reviewed literature, the Ontario Case Costing Initiative and case costing data from a large Canadian hospital. A 2013 meta-analysis was used to provide efficacy data on the reduction of health care resources associated with surgical management. The outcomes are reflective of a hospital that treats 10 patients with flail chest per year. The model takes into consideration costs associated with surgery, length of stay and the common complications associated with flail chest. A multivariate sensitivity analysis utilizing a Monte Carlo simulation was conducted on economic and clinical parameters to ensure robustness. Results: The model found that shifting the treatment of flail chest from supportive to surgical management decreased the number of ventilation days from 13.9 to 6.4 and the total hospital stay from 27.2 to 18.4 days. It also found a reduction in the incidence of complications such as tracheostomies from 78.94% to 18% and pneumonia from 89.47% to 62%. Accounting for the additional costs associated with fixation devices and surgical management, the model establishes that surgical rib fixation for flail chest has the potential to provide a Canadian hospital with an annual net cost savings of CAD
Value in Health | 2012
Lj Goldstein
214,660. cOnclusiOns: Shifting the treatment of flail chest from supportive to surgical management with contoured titanium plates is a cost-effective solution for Canadian hospitals.
Value in Health | 2017
Bp Chen; Lj Goldstein; H Alder; J Brown; Hang Cheng
Value in Health | 2017
D Wei; M Gutierrez; Lj Goldstein; Ss Johnston
Value in Health | 2017
D Wei; M Gutierrez; Lj Goldstein
Value in Health | 2017
Em Ammann; Lj Goldstein; Ss Johnston
Value in Health | 2016
Ss Johnston; A Yoo; C Hsiao; M Daskiran; Lj Goldstein
Value in Health | 2015
Lj Goldstein; D.A. Ondrejicka
Value in Health | 2015
D.A. Ondrejicka; Lj Goldstein
Value in Health | 2014
Lj Goldstein