Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Lorena Buitrago.
Anesthesia & Analgesia | 2006
Félix Montes; Darío Echeverri; Lorena Buitrago; Isabel Ramírez; Juan Camilo Giraldo; Javier D. Maldonado; Juan P. Umana
BACKGROUND: Levosimendan, an inotropic drug that enhances myocardial contractility through myofilment calcium sensitazion, induces peripheral vasodilation via opening ATP-dependent K+ channels. It is unknown whether this drug can be used for the treatment of perioperative vasospasm of arterial conduits used for coronary artery bypass grafting. METHODS: We investigated the effects of levosimendan on human internal mammary artery (IMA) specimens taken from patients undergoing coronary artery bypass surgery. The rings were carefully prepared and placed between two wire hooks in organ bath chambers and then constricted submaximally with norepinephrine and thromboxane A2 analog (U46619). Nitroglycerin, milrinone, and levosimendan were separately added in a cumulative fashion and concentration response curves for relaxation were constructed. In parallel experiments, the response to levosimendan was evaluated on rings with and without functional endothelium. Levosimendan prevention of norepinephrine-induced contraction was also estimated. RESULTS: Nitroglycerin, milrinone, and levosimendan completely reversed the contraction of the IMA segments induced by U46619 and norepinephrine. Levosimendan produced a potent, concentration-dependent preventive effect on the norepinephrine-induced contraction of IMA. The responses to levosimendan were similar in preparations with or without endothelium.
Revista Colombiana de Cardiología | 2005
Darío Echeverri; Lorena Buitrago; Félix Montes
Clínica e Investigación en Arteriosclerosis | 2008
Darío Echeverri; Lorena Buitrago; Alexandra Delgadillo; Marcela Beltrán; Félix Montes
Revista Colombiana de Cardiología | 2005
Darío Echeverri; Lorena Buitrago; Félix Montes; Ingrid Mejía; María del Pilar González
Biomedica | 2008
Darío Echeverri; Félix Montes; Alexandra Delgadillo; Marcela Beltrán; Lorena Buitrago
Revista Colombiana de Cardiología | 2007
Darío Echeverri; Félix Montes; Lorena Buitrago; Alexandra Delgadillo; Marcela Beltrán; Amílcar Salgado
Revista Colombiana de Cardiología | 2005
María Fernanda Escobar; Darío Echeverri; Lorena Buitrago; Claudia Espitia; María del Pilar Delgado; Carlos Jaramillo; Javier Maldonado; Juan P. Umana
Revista Colombiana de Anestesiología | 2005
Félix Montes; Juan Camilo Giraldo; José Domingo Rincón; Darío Echeverri; Lorena Buitrago; Isabel Ramírez
Archive | 2005
L Buitrago; N Guzmán; N Fernández; I Mejía; María del Pilar González; F Montes; Lorena Buitrago; Alexandra Delgadillo; Natalia Guzmán; Nicolás Fernández; Ingrid Mejía; P. G Onzález; Félix Montes; Darío Echeverri
Rev. colomb. cardiol | 2004
Lorena Buitrago; Gladys Barrera; Carolina Zúñiga; Diana Acosta; Félix Montes; Darío Echeverri