Lori Buchanan

Neural Correlates of Lexical Access during Visual Word Recognition

People can discriminate real words from nonwords even when the latter are orthographically and phonologically word-like, presumably because words activate specific lexical and/or semantic information. We investigated the neural correlates of this identification process using event-related functional magnetic resonance imaging (fMRI). Participants performed a visual lexical decision task under conditions that encouraged specific word identification: Nonwords were matched to words on orthographic and phonologic characteristics, and accuracy was emphasized over speed. To identify neural responses associated with activation of nonsemantic lexical information, processing of words and nonwords with many lexical neighbors was contrasted with processing of items with no neighbors. The fMRI data showed robust differences in activation by words and word-like nonwords, with stronger word activation occurring in a distributed, left hemisphere network previously associated with semantic processing, and stronger nonword activation occurring in a posterior inferior frontal area previously associated with grapheme-to-phoneme mapping. Contrary to lexicon-based models of word recognition, there were no brain areas in which activation increased with neighborhood size. For words, activation in the left prefrontal, angular gyrus, and ventrolateral temporal areas was stronger for items without neighbors, probably because accurate responses to these items were more dependent on activation of semantic information. The results show neural correlates of access to specific word information. The absence of facilitatory lexical neighborhood effects on activation in these brain regions argues for an interpretation in terms of semantic access. Because subjects performed the same task throughout, the results are unlikely to be due to task-specific attentional, strategic, or expectancy effects.

Characterizing semantic space: Neighborhood effects in word recognition

A specification of the structural characteristics of the mental lexicon is a central goal in word recognition research. Of various word-level characteristics, semantics remains the most resistant to this endeavor. Although there are several theoretically distinct models of lexical semantics with fairly clear operational definitions (e.g., in terms of feature sharing, category membership, associations, or cooccurrences), attempts to empirically adjudicate between these different models have been scarce. In this paper, we present several experiments in which we examined the effects of semantic neighborhood size as defined by two models of lexical semantics—one that defines semantics in terms of associations, and another that defines it in terms of global co-occurrences. We present data that address the question of whether these measures can be fruitfully applied to examinations of lexical activation during visual word recognition. The findings demonstrate that semantic neighborhood can predict performance on both lexical decision and word naming.

Long-term sequelae of hearing impairment in congenital hypothyroidism☆☆☆★★★

Hearing loss and its functional consequences were evaluated retrospectively in children with congenital hypothyroidism. From a cohort of 101 children followed longitudinally to evaluate newborn screening, 75 with previous hearing tests were studied. Fifteen (20%) were found to have hearing problems. Of these, nine had unilateral or sensorineural loss mostly at high frequencies, five had a conductive loss, and one had both problems. Hearing impaired children differed from children with normal hearing in age of treatment onset (22 vs 14 days) but not disease severity or duration. A comparison of language and auditory processing skills at ages 3, 5, and 7 years revealed that early speech was delayed in hearing impaired children, whereas deficits persisted in later receptive language and auditory discrimination skills. Comparing hearing impaired children and children with normal hearing with matched control subjects at grade 3 showed that hearing impaired children were poorer readers because of less adequate phonologic processing skills.

A reexamination of the visuospatial deficit in turner syndrome: Contributions of working memory

Studies describing deficits in children with Turner Syndrome (TS) typically report that visual and spatial processing are impaired relative to verbal processing (Rovet & Netley, 1982). The exact nature of this deficit is not entirely clear, however, because the tasks that have been used to date (e.g., mental rotation, part‐whole and left‐right decisions, etc.) do not distinguish between what Kosslyn (1980) described as the two components of visual processing: locating an object in space (where?) and determining the identity of an object (what?). We report findings from an experiment designed to examine visual processing and working memory in children with TS and normal control children. However, unlike previous examinations of visuospatial processing in TS, the reported experiments tease apart what and where aspects of the visual system. Moreover, they examine separately the contributions of both visual and verbal working memory to visuospatial processing. Differences between children with TS and normal c...

The effect of semantic distance in yes/no and go/no-go semantic categorization tasks.

The effect of semantic distance (Lund & Burgess, 1996) was examined in three semantic categorization experiments. Experiment 1, a yes/no task that required participants to make animal/nonanimal judgments by responding to both sets of stimuli (Forster & Shen, 1996), revealed no effect of semantic distance. Experiment 2, a go/no-go task that required participants to respond to only the experimental (i.e., nonanimal) items, revealed a large effect of semantic distance. In addition, response latencies were longer and error rates were lower to the experimental items in Experiment 2 than to those in Experiment 1. These findings were replicated in Experiment 3, in which semantic distance and task condition were manipulated within subjects. We conclude that these results are consistent with (1) the view that the go/no-go tasks elicited more extensive processing of the experimental items and (2) a connectionist account of semantic activation, whereby processing is facilitated by the presence of semantic neighbors.

Semantics and semantic errors: Implicit access to semantic information from words and nonwords in deep dyslexia

In this paper we describe dissociations of implicit versus explicit access to semantic information in a patient with deep dyslexia. This acquired reading disorder is characterized by the production of morphological (e.g., SLEEP read as SLEEPING) and semantic errors (e.g., HEART read as BLOOD) and consequently provides a potential window into the operation of both aspects of the language system. The deep dyslexic patient in this study (JO) demonstrated implicit semantic access to items in a number of tasks despite the fact that she was unable to correctly read these items aloud. The findings from this study are consistent with a model of lexical deficits that distinguishes between explicit and implicit access to lexical representations on the basis of inhibitory processes.

False Memories and Semantic Lexicon Arrangement

A description of semantic lexicon arrangement is a central goal in examinations of language processing. There are a number of ways in which this description has been cast and a host of different mechanisms in place for providing operational descriptions (e.g., feature sharing, category membership, associations, and co-occurrences). We first review two views of the structure of semantic space and then describe an experiment that attempts to adjudicate between these two views. The use of a false memory paradigm provides us with evidence that supports the notion that the semantic lexicon is arranged more by association than by categories or features.

The Probability of the Least Likely Non-Length-Controlled Bigram Affects Lexical Decision Reaction Times

The frequency effect, by which high frequency words are recognized with more ease than low frequency words, is one of the most robust effects in cognitive psychology. Frequency interacts with many word-level variables, to the extent that most effects reported in word recognition literature have an impact only on low frequency words. This has been taken as evidence that high frequency words are accessed in a special way, via either an addressed pathway as in the dual-route model or an assembled pathway as in a PDP model. Under either model, sublexical effects should have no bearing on the ease with which representations for high frequency words are accessed. In this article, however, we describe a series of studies that examine a sublexical effect (namely nonlength controlled minimal bigram frequency) that is only found for high frequency words, suggesting that sublexical processing must play a role in the recognition of even high frequency words.

WINDSOR: Windsor improved norms of distance and similarity of representations of semantics

Lexical co- occurrence models of semantic memory form representations of the meaning of a word on the basis of the number of times that pairs of words occur near one another in a large body of text. These models offer a distinct advantage over models that require the collection of a large number of judgments from human subjects, since the construction of the representations can be completely automated. Unfortunately, word frequency, a well-known predictor of reaction time in several cognitive tasks, has a strong effect on the co- occurrence counts in a corpus. Two words with high frequency are more likely to occur together purely by chance than are two words that occur very infrequently. In this article, we examine a modification of a successful method for constructing semantic representations from lexical co- occurrence. We show that our new method eliminates the influence of frequency, while still capturing the semantic characteristics of words.

A diffusion model account of normal and impaired readers.

Acquired aphasics and dyslexics with even very profound word reading impairments have been shown to perform relatively well on the lexical decision task, but direct contrasts with unimpaired participants data is often complicated by extremely long reaction times for patient data. The dissociation between lexical decision and word naming performance shown by these patients is of theoretical importance, and here we present an analysis of processing underlying the lexical decision task. We are able to determine what aspects of performance are affected by acquired aphasics in the lexical decision task. We fit lexical decision data from aphasic patients and from normal readers with a sequential sampling model (the diffusion model) that simultaneously considers reaction time and accuracy. This model provides a powerful means of assessing processes involved in impaired and unimpaired lexical decision. Our results suggest that lexical decision may tap impairments at both a linguistic and a nonlinguistic level. These impairments combine to make patients produce the exaggerated lexical decision reaction times typical of neurolinguistic patients: we demonstrate that patients have compromised decision and nondecision processes but that the quality of the information upon which they base their decisions is not much different from that of unimpaired participants.