Lori S. Waddell

Critical Care Nutrition: Routes of Feeding

Nutrition is an integral part of the management of the critically ill patient. Nutritional support can be provided by either parenteral or enteral routes. Whenever possible, enteral nutrition is the method of choice, as it reduces complication rates and improves outcome. Potential choices for enteral feeding include nasoesophageal, esophagostomy, gastrostomy, jejunostomy, and transpyloric feeding tubes. The modes of parenteral and enteral nutrition are reviewed individually, including indications and selection of appropriate routes of feeding, methods of tube placement, and benefits and risks associated with each feeding approach.

Anticoagulant rodenticide screening in dogs: 123 cases (1996–2003)

OBJECTIVE To identify dogs with anticoagulant rodenticide (AR) screens submitted, determine whether detected concentrations of the anticoagulants correlated with severity of clinical signs for dogs with positive results on AR screens, and identify the most common disease processes present and the prognosis for those with negative AR screens. DESIGN Retrospective case series. ANIMALS 123 dogs. PROCEDURES History, signalment, clinical signs, physical examination findings, PCV, total solids concentration, prothrombin time, activated partial thromboplastin time, platelet count, AR concentrations, duration of hospitalization, blood products administered, final diagnosis, and outcome were recorded from medical records of dogs that underwent AR toxicology screenings. RESULTS 75 of 123 (60.9%) dogs tested positive for AR. Dogs tested positive for brodifacoum, diphacinone (also called diphenadione), and chlorophacinone. Dogs with positive AR screenings weighed significantly less, received significantly more fresh frozen plasma, had significantly longer initial prothrombin time, and were significantly more likely to survive, compared with those with negative screens. Anticoagulant rodenticide concentrations ranged from trace amounts to 1,120 parts per billion and were not correlated with any recorded parameter. The most common conditions diagnosed in the 48 dogs with negative screens included neoplasia in 15 (31.3%), immune-mediated disease in 7 (14.6%), and gastrointestinal bleeding in 5 (10.4%) dogs. CONCLUSIONS AND CLINICAL RELEVANCE AR concentrations were not correlated with severity of clinical signs or the degree of prolongation of coagulation times in this series of patients. Patients with severe coagulopathies but negative results of AR screening had a poor prognosis, with neoplasia as the most common diagnosis. Anticoagulant rodenticide intoxication had the best prognosis, with a survival rate of 98.7% in this study.

Pulse oximetry and capnometry.

Respiratory dysfunction is common in veterinary patients and various techniques have been developed to rapidly and accurately monitor pulmonary gas exchange. Pulse oximetry and capnometry are tools that allow for continuous evaluation of pulmonary function. Methodology, indications, and limitations of pulse oximetry and capnometry are discussed in this article. Both techniques are useful for monitoring critically ill or anesthetized patients; however, limitations to their use exist which underscore the need for intermittent arterial blood gas analysis.

Blood Gas Analyzers

Acid-base and respiratory disturbances are common in sick and hospitalized veterinary patients; therefore, blood gas analyzers have become integral diagnostic and monitoring tools. This article will discuss uses of blood gas analyzers, types of samples that can be used, sample collection methods, potential sources of error, and potential alternatives to blood gas analyzers and their limitations. It will also discuss the types of analyzers that are available, logistical considerations that should be taken into account when purchasing an analyzer, and the basic principles of how these analyzers work.

General approach to respiratory distress

It is essential that patients in respiratory distress are recognized immediately. Respiratory distress is caused by hypoxaemia, hypercapnia, or a significant increase in the work of breathing. This chapter covers diagnosis, emergency stabilization, approach to undiagnosed respiratory distress, pulmonary function testing in the dyspnoeic patient and intubation and positive pressure ventilation.

In Memoriam: Lesley Geraldine King

Dr. Altshuler received both her Bachelor of Arts in Psychology (1978) and her M.D. degree (1982) from Cornell University, where she was a member of the Quill and Dagger society. From 1982 to 1983 she interned at UCLA’s Center for Health Sciences/Wadsworth Veterans Administration. She completed her residency at UCLA’s Neuropsychiatric Institute & Hospital in 1986. Dr. Altshuler completed a two-year fellowship at the Biological Psychiatry Branch of the National Institute of Mental Health (NIMH) from 1987 to 1989.

Perioperative Acid-Base and Electrolyte Disturbances

Obtaining and interpreting blood gas and electrolyte levels is essential in the management of perioperative veterinary patients. Metabolic and electrolyte alterations are common in critically ill surgical patients, and can lead to alterations in cardiovascular function, neurologic status, respiratory function, and even response to various drug therapies. Several common perioperative conditions are discussed in this article, including metabolic disturbances, electrolyte abnormalities (hyponatremia and hypernatremia, hyperkalemia), and respiratory abnormalities.