Lorraine Brilla

Effect of strength training on orthostatic hypotension in older adults.

PURPOSE This preliminary study attempted to identify the frequency of orthostatic hypotension (OH) in community dwelling older adults who volunteered to participate in an 8-week, heavy-resistance, strength-training program. It also assessed the effect of the strength-training program on OH. METHODS From a larger study (n = 53) on high-resistance strength training in older adults (mean age 71.4 +/- 6.6 years), a subset of subjects (n = 24), mean age 71.0 +/- 5.8 years, was evaluated who met at least one criterion for OH. All subjects were tested for resting blood pressures (BP) and heart rates (HR) in the supine, sitting, and standing positions. Also noted was their response to orthostatism in rising from a cot after 10 minutes and rising from a chair after 5 minutes. The subset was not different from the overall group in gender ratio, age, or effect of medication on BP. The treatment was an 8-week strength-training program at 80% of their one repetition maximum. RESULTS Significant changes (P < 0.05) were shown in supine diastolic BP (+3.2 mm Hg), sitting systolic BP (-3.9), and standing HR (+4.9 beats per minute). In response to the orthostatic challenge, significant (P < 0.05) improvements were shown in systolic BP (+9.7 mm Hg), diastolic BP (+4.7), and HR (+3.2 beats per minute) for the rise from chair, and in diastolic BP (+6.7 mm Hg) rise from the cot. CONCLUSIONS These data show that OH is not uncommon (45%) in community dwelling older adults. A strength training program in older adults has little effect on resting BP, but elicits a positive adaptation to an orthostatic challenge.

Magnesium-creatine supplementation effects on body water

This study evaluated magnesium-creatine (MgCre) supplementation on body water and quadriceps torque. Maltodextran (Placebo), Mg oxide plus Cre (MgO-Cre), and Mg-creatine chelate (MgC-Cre) at 800 mg Mg and 5 g Cre per day were used for 2 weeks in 35 subjects in a random assignment, blinded study. Pre-post measures were completed with bioimpedance to determine total body water (TBW), extracellular water (ECF), and intracellular water (ICF), and an isokinetic device at 180 degrees per second for knee extension peak torque (T), total work (W), and power (PWR). Body weights increased for both treatment groups, MgO-Cre Delta 0.75 kg (P <.05) and MgC-Cre Delta 0.4 kg (P =.07). Significant pre-post differences (P <.05) were noted only for MgC-Cre in ICW (26.29 v 28.01 L) and ECW (15.75 v 14.88 L). MgC-Cre had significant peak T (Nm) increase (124.5 v135.8, P <.05), while MgO-Cre (116.4 v 124.9, P =.06) and placebo (119.8 v 123.7, P =.343) did not. Both treatment groups had increased PWR (P <.05). MgC-Cre affects cellular fluid compartments. The peak torque changes were significant only in the MgC-Cre group, which had increases in ICW that may infer more muscular creatine due to its osmotic effect, and with increased cellular hydration, perhaps increased protein synthesis.

Effect of sonic driving on maximal aerobic performance

The study purpose was to evaluate antecedent binaural stimulation (ABS) on maximal aerobic physical performance. Twenty‐two healthy, physically active subjects, 21–34 years, randomly received one of two preparations for each session: 15 min of quiet (BLANK) or percussive sonic driving at 200+ beats per minute (bpm) using a recorded compact disc (FSS, Mill Valley, CA) with headphones (ABS). Baseline HR, blood pressure (BP), and breathing frequency (fbr) were obtained. During each condition, HR and fbr were recorded at 3‐min intervals. The graded maximal treadmill testing was administered immediately postpreparation session on separate days, with at least 48 h rest between sessions. There were significant differences in the antecedent period means between the two conditions, ABS (HR: 70.2 ± 10.7 bpm; fbr: 18.5 ± 3.3 br min−1; BP: 134.5/87.9 ± 13.6/9.2 mm Hg) and BLANK (HR: 64.6 ± 7.9; fbr: 14.3 ± 2.9; BP: 126.7/80.3 ± 12.1/8.6). Differences were noted for each 3‐min interval and pre‐ postantecedent period. The maximal graded exercise test (GXT) results showed that there was a small but significant (P < 0.05), increase in maximal VO2 in the ABS (49.8 ± 6.8 ml · kg−1 · min−1) vs. BLANK (46.7 ± 8.7) conditions. Related to that finding was a slight increase (0.5 min) in time to exhaustion (P < 0.05). There were no significant differences in HR or RPE (P > 0.05). There may be a latency to ABS related to entrainment or imagery‐enhanced warm‐up. Am. J. Hum. Biol. 12:558–565, 2000.