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Dive into the research topics where Luc Ouellet is active.

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Featured researches published by Luc Ouellet.


Bioorganic & Medicinal Chemistry Letters | 2008

Efficient parallel synthesis of macrocyclic peptidomimetics.

Eric Marsault; Hamid R. Hoveyda; René Gagnon; Mark L. Peterson; Martin Vezina; Carl Saint-Louis; Annick Landry; Jean François Pinault; Luc Ouellet; Sophie Beauchemin; Sylvie Beaubien; Axel P. Mathieu; Kamel Benakli; Zhigang Wang; Martin Brassard; David Lonergan; François Bilodeau; Mahesh Ramaseshan; Nadia Fortin; Ruoxi Lan; Shigui Li; Fabrice Galaud; Véronique Plourde; Manon Champagne; Annie Doucet; Patrick Bherer; Maude Gauthier; Gilles Olsen; Gérald Villeneuve; Shridhar Bhat

A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studies on the macrocyclization step are reported.


Journal of Medicinal Chemistry | 2011

Optimization of the Potency and Pharmacokinetic Properties of a Macrocyclic Ghrelin Receptor Agonist (Part I): Development of Ulimorelin (TZP-101) from Hit to Clinic

Hamid R. Hoveyda; Eric Marsault; René Gagnon; Axel P. Mathieu; Martin Vezina; Annick Landry; Zhigang Wang; Kamel Benakli; Sylvie Beaubien; Carl Saint-Louis; Martin Brassard; Jean François Pinault; Luc Ouellet; Shridhar Bhat; Mahesh Ramaseshan; Xiaowen Peng; Laurence Foucher; Sophie Beauchemin; Patrick Bherer; Daniel F. Veber; Mark L. Peterson; Graeme Fraser


Journal of Medicinal Chemistry | 2006

Discovery of a new class of macrocyclic antagonists to the human motilin receptor.

Eric Marsault; Hamid R. Hoveyda; Mark L. Peterson; Carl Saint-Louis; Annick Landry; Martin Vezina; Luc Ouellet; Zhigang Wang; Mahesh Ramaseshan; Sylvie Beaubien; Kamel Benakli; Sophie Beauchemin; Robert Deziel; Theo Peeters; Graeme Fraser


Archive | 2004

Spatially-defined macrocycles incorporating peptide bond surrogates

Pierre Deslongchamps; Yves L. Dory; Luc Ouellet; Gérald Villeneuve; Mahesh Ramaseshan; Daniel Fortin; Mark L. Peterson; Hamid R. Hoveyda; Sylvie Beaubien; Eric Marsault


Archive | 2000

Combinatorial Synthesis of Libraries of Macrocyclic Compounds Useful in Drug Discovery

Pierre Deslongchamps; Yves L. Dory; Gilles Berthiaume; Luc Ouellet; Ruoxi Lan


Archive | 2008

Macrocyclic Ghrelin Receptor Modulators and Methods of Using the Same

Hamid R. Hoveyda; Graeme Fraser; Kamel Benakli; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Ouellet; Mark L. Peterson; Zhigang Wang


Archive | 2004

Spatially-defined macrocyclic compounds useful for drug discovery

Pierre Deslongchamps; Yves L. Dory; Kamel Benakli; Eric Marsault; Luc Ouellet; Mahesh Ramaseshan; Martin Vezina; Daniel Fortin; Ruoxi Lan; Shigui Li; Gérald Villeneuve; Hamid Hoveyda; Sylvie Beaubien; Mark L. Peterson


Archive | 2004

Conformationally-controlled biologically active macrocyclic small molecules as motilin antagonists or ghrelin agonists

Pierre Deslongchamps; Yves L. Dory; Mark L. Peterson; Kamel Benakli; Eric Marsault; Luc Ouellet; Mahesh Ramaseshan; Martin Vezina; Daniel Fortin; Ruoxi Lan; Shigui Li; Gérald Villeneuve; Hamid Hoveyda; Sylvie Beaubien; Graeme Fraser


Synlett | 1997

Synthesis of a 14β-Hydroxysteroid Using the Transannular Diels-Alder Strategy

Luc Ouellet; P. Langlois; Pierre Deslongchamps


Archive | 2012

Processes for intermediates for macrocyclic compounds

Eric Marsault; Luc Ouellet; Hamid R. Hoveyda

Collaboration


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Eric Marsault

Université de Sherbrooke

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Yves L. Dory

Université de Sherbrooke

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Ruoxi Lan

Université de Sherbrooke

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Daniel Fortin

Université de Sherbrooke

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