Lucas L. Kulczycki

Effect of Pyridoxine Administration on the Urinary Excretion of Oxalic Acid, Pyridoxine, and Related Compounds in Mongoloids and Nonmongoloids

T HE RESULTS of two unrelated studies ill this laboratory stimulated the present investigation. Gershoff ci al.tm have reported evidence suggesting the possibility of a methylating defect in mongoloids. In this same study a slight but statistically significant decrease in xanthurenic acid excretion following a tryptophan load test was observed in mrmongoloids as comnpared to nonmongoloid controls. In another study Gershoff el al.2 observed that in vitamin B6-deficient cats large quantities of oxalic acid were excreted in the urine, which resulted in severe kidney damage. In the present work the effect of load tests of pyridoxine and folic acid in mongoloids and nonmongoloids has been studied.

Resection of pulmonary lesions associated with cystic fibrosis of the pancreas.

IT is becoming increasingly clear that the pulmonary involvement in cystic fibrosis of the pancreas is by far the most important and serious manifestation of this disease. For many years the pancre...