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Featured researches published by Lucy Smith.


Bulletin of The World Health Organization | 2008

Equity and child-survival strategies

E.K. Mulholland; Lucy Smith; Ilona Carneiro; Heiko Becher; Deborah Lehmann

Recent advances in child survival have often been at the expense of increasing inequity. Successive interventions are applied to the same population sectors, while the same children in other sectors consistently miss out, leading to a trend towards increasing inequity in child survival. This is particularly important in the case of pneumonia, the leading cause of child death, which is closely linked to poverty and malnutrition, and for which effective community-based case management is more difficult to achieve than for other causes of child death. The key strategies for the prevention of childhood pneumonia are case management, mainly through Integrated Management of Childhood Illness (IMCI), and immunization, particularly the newer vaccines against Haemophilus influenzae type b (Hib) and pneumococcus. There is a tendency to introduce both interventions into communities that already have access to basic health care and preventive services, thereby increasing the relative disadvantage experienced by those children without such access. Both strategies can be implemented in such a way as to decrease rather than increase inequity. It is important to monitor equity when introducing child-survival interventions. Economic poverty, as measured by analyses based on wealth quintiles, is an important determinant of inequity in health outcomes but in some settings other factors may be of greater importance. Geography and ethnicity can both lead to failed access to health care, and therefore inequity in child survival. Poorly functioning health facilities are also of major importance. Countries need to be aware of the main determinants of inequity in their communities so that measures can be taken to ensure that IMCI, new vaccine implementation and other child-survival strategies are introduced in an equitable manner.


Tropical Medicine & International Health | 2007

Is the Expanded Programme on Immunisation the most appropriate delivery system for intermittent preventive treatment of malaria in West Africa

Daniel Chandramohan; Jayne Webster; Lucy Smith; Timothy Awine; Seth Owusu-Agyei; Ilona Carneiro

Objective  To investigate the coverage and equity of the Expanded Programme on Immunisation (EPI) and its effect on age schedule, seasonality of malaria risk, and linked intermittent preventive treatment (IPT) in West Africa.


Malaria Journal | 2010

From fever to anti-malarial: the treatment-seeking process in rural Senegal

Lucy Smith; Jane Bruce; Lamine Gueye; Anthony Helou; Rodio Diallo; Babacar Gueye; Caroline Jones; Jayne Webster

BackgroundCurrently less than 15% of children under five with fever receive recommended artemisinin-combination therapy (ACT), far short of the Roll Back Malaria target of 80%. To understand why coverage remains low, it is necessary to examine the treatment pathway from a child getting fever to receiving appropriate treatment and to identify critical blockages. This paper presents the application of such a diagnostic approach to the coverage of prompt and effective treatment of children with fever in rural Senegal.MethodsA two-stage cluster sample household survey was conducted in August 2008 in Tambacounda, Senegal, to investigate treatment behaviour for children under five with fever in the previous two weeks. The treatment pathway was divided in to five key steps; the proportion of all febrile children reaching each step was calculated. Results were stratified by sector of provider (public, community, and retail). Logistic regression was used to determine predictors of treatment seeking.ResultsOverall 61.6% (188) of caretakers sought any advice or treatment and 40.3% (123) sought any treatment promptly within 48 hours. Over 70% of children taken to any provider with fever did not receive an anti-malarial. The proportion of febrile children receiving ACT within 48 hours was 6.2% (19) from any source; inclusion of correct dose and duration reduced this to 1.3%. The proportion of febrile children receiving ACT within 48 hours (not including dose & duration) was 3.0% (9) from a public provider, 3.0% (9) from a community source and 0.3% (1) from the retail sector. Inclusion of confirmed diagnosis within the public sector treatment pathway as per national policy increases the proportion of children receiving appropriate treatment with ACT in this sector from 9.4% (9/96) to an estimated 20.0% (9/45).ConclusionsProcess analysis of the treatment pathway for febrile children must be stratified by sector of treatment-seeking. In Tambacounda, Senegal, interventions are needed to increase prompt care-seeking for fever, improve uptake of rapid diagnostic tests at the public and community levels and increase correct treatment of parasite-positive patients with ACT. Limited impact will be achieved if interventions to improve prompt and effective treatment target only one step in the treatment pathway in any sector.


Disaster Prevention and Management | 2006

The drinking water response to the Indian Ocean tsunami, including the role of household water treatment

Thomas Clasen; Lucy Smith; Jeff Albert; Andrew Bastable; Jean‐Francois Fesselet

Purpose – To document the drinking water component of the humanitarian response to the Great Sumatra‐Andaman earthquake of December 26, 2004, including a focus on the promotion of household water treatment (HHWT)/safe storage to minimize the spread of diarrhoeal disease.Design/methodology/approach – Firsthand accounts of the response effort, interviews, and literature review.Findings – The combined efforts to mobilize a drinking water response were timely, comprehensive and effective. HHWT/safe storage efforts (other than the continued promotion of boiling) appeared to play only a secondary role in the initial response to the disaster for a variety of reasons.Practical implications – The enormity of this disaster and the unprecedented scale of the relief effort limit the broad lessons that can be learned at this time.Originality/value – Shows that there is a clear need to continue to take steps to minimize the risks of waterborne diseases following natural disasters, develop and disseminate practical solu...


Bulletin of The World Health Organization | 2010

Intermittent preventive treatment for malaria in infants: a decision-support tool for sub-Saharan Africa

Ilona Carneiro; Lucy Smith; Amanda Ross; Arantxa Roca-Feltrer; Brian Greenwood; Joanna Schellenberg; Thomas Smith; David Schellenberg

OBJECTIVE To develop a decision-support tool to help policy-makers in sub-Saharan Africa assess whether intermittent preventive treatment in infants (IPTi) would be effective for local malaria control. METHODS An algorithm for predicting the effect of IPTi was developed using two approaches. First, study data on the age patterns of clinical cases of Plasmodium falciparum malaria, hospital admissions for infection with malaria parasites and malaria-associated death for different levels of malaria transmission intensity and seasonality were used to estimate the percentage of cases of these outcomes that would occur in children aged <10 years targeted by IPTi. Second, a previously developed stochastic mathematical model of IPTi was used to predict the number of cases likely to be averted by implementing IPTi under different epidemiological conditions. The decision-support tool uses the data from these two approaches that are most relevant to the context specified by the user. FINDINGS Findings from the two approaches indicated that the percentage of cases targeted by IPTi increases with the severity of the malaria outcome and with transmission intensity. The decision-support tool, available on the Internet, provides estimates of the percentage of malaria-associated deaths, hospitalizations and clinical cases that will be targeted by IPTi in a specified context and of the number of these outcomes that could be averted. CONCLUSION The effectiveness of IPTi varies with malaria transmission intensity and seasonality. Deciding where to implement IPTi must take into account the local epidemiology of malaria. The Internet-based decision-support tool described here predicts the likely effectiveness of IPTi under a wide range of epidemiological conditions.


Malaria Journal | 2010

The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings

Arantxa Roca-Feltrer; Ilona Carneiro; Lucy Smith; Joanna Schellenberg; Brian Greenwood; David Schellenberg


Malaria Journal | 2010

Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: user acceptability

Lucy Smith; Caroline Jones; Rose Odotei Adjei; Gifty Antwi; Nana A Afrah; Brian Greenwood; Daniel Chandramohan; Harry Tagbor; Jayne Webster


American Journal of Tropical Medicine and Hygiene | 2009

Review: Provider Practice and User Behavior Interventions to Improve Prompt and Effective Treatment of Malaria: Do We Know What Works?

Lucy Smith; Caroline Jones; Sylvia Meek; Jayne Webster


Malaria Journal | 2009

A simple method for defining malaria seasonality.

Arantxa Roca-Feltrer; Joanna Schellenberg; Lucy Smith; Ilona Carneiro


Transactions of The Royal Society of Tropical Medicine and Hygiene | 2007

Smoke and malaria: are interventions to reduce exposure to indoor air pollution likely to increase exposure to mosquitoes?

Adam Biran; Lucy Smith; Jo Lines; Jeroen H. J. Ensink; M. M. Cameron

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Deborah Lehmann

University of Western Australia

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