Luigi Maria Pernice
University of Florence
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Diseases of The Colon & Rectum | 2001
Luigi Maria Pernice; Barbara Bartalucci; Lapo Bencini; Alessandro Borri; Catarzi S; Katrin Kröning
PURPOSE: We present a retrospective clinical study concerning the preliminary experience with the circular stapler in the treatment of hemorrhoids. Early results, complications, and long-term follow-up are revisited. METHODS: Fifty-six consecutive patients with second-, third-, and fourth-degree hemorrhoids were included in the study. Data about operation, early postoperative results, and follow-up at one, two, and four weeks were collected. Patients were also contacted by phone after a long-term follow-up (mean, 33 (range, 5–120) months). RESULTS: Every operation attempted was successfully terminated. The length of the operation was less than 15 minutes. No major bleeding or anastomotic disruption occurred. Six patients (13 percent) who underwent spinal or epidural anesthesia had urinary retention. One patient (1.7 percent) had minor bleeding, and four patients (7.1 percent) experienced transient edema of the anastomotic ring after the operation. None needed further treatments. The mean analgesic requirement was 1.4 (range, zero to eight) ketorolac 30-mg injections; 23 patients (41 percent) received no analgesics, and seven patients (12 percent) required a single extra dose of opiates (10 mg morphine cloridrate). Length of hospital stay was between 0 and 11 (mean, 2.7) days, but 20 patients (35 percent) received an additional operation for coexisting surgical disease. At one week, almost all patients experienced little pain at digital inspection and little bleeding after defecations. No anastomotic leakage, wound infection, or healing delay was found. Three patients (5.3 percent) experienced wound edema and pain during defecation. Two weeks later, one patient (1.7 percent) suffered from painful defecation and ten patients (17 percent) reported minor bleeding, but all returned to normal activities. No pain during defecation, bleeding, stenosis, soiling, incontinence, or other anal symptoms were found at one month after the operation, and all patients were well. All patients were contacted by phone 5 to 120 (mean, 33) months later, and all were pleased with the results of this procedure. There were no symptomatic recurrences. DISCUSSION: Our study confirms the feasibility of circular stapler hemorrhoidectomy in the treatment of hemorrhoids. Complications and postoperative pain were minimal. There were no recurrences during long-term follow-up. CONCLUSION: Mechanical hemorrhoidectomy is a promising new option in the treatment of all patients eligible for a surgical approach.
Diseases of The Colon & Rectum | 1986
Francesco Andreoli; Filippo Balloni; Alfio Bigiotti; Paolo Lombardi; Luigi Maria Pernice; Oscar Ronchi; Francesco Taruffi
The effect of sacral resection up to S-2 has been investigated in two patients with “chordomas”, surgical division of the spinal roots was unilateral and bilateral, respectively. Anal manometry, electromyography of the sphincters, and the ascertaining of tactile, thermic, and painful stimuli perception in the perineum and anal canal were executed to determine the effects of denervation on anorectal continence. Vesical function was tested by vesical manometry. Results differ strongly between the two patients: the first, with unilateral loss of S-2, has perfect anorectal continence. The second, with bilateral loss of S-2, is incontinent and unable to discriminate rectal contents. It is sufficient to retain only one S-2 root for the maintenance of physiologic continence, including distinction between different types of bowel contents (gaseous or solid) passing through the anal canal. The same is true concerning bladder function.
Journal of Gastrointestinal Surgery | 2006
Luigi Maria Pernice; Maurizio Bartolucci; Valentina Mori; Luca Ponchietti; Alessandro Tedone
Bowel herniation through the foramen of Winslow is among the rarest of internal hernias, accounting for less than 0.8%. In its origin, a pivotal role is played by some anatomic variations, or anomalies such as the increased mobility of the right transverse colon, and maybe the exceedingly large bore of the foramen itself. The first case of hernia through the foramen of Winslow was reported by Blandin in 1834. Since then, no more that 200 new cases have been described. Diagnosis usually is established during surgery while treating a bowel obstruction. Only in an exceedingly small group of patients is diagnosis achieved preoperatively on the basis of radiological findings. We describe a preoperatively diagnosed case of transverse colon herniation through the foramen of Winslow, showing a portal vein narrowing and periportal lymphedema at computed tomography (CT). To the best of our knowledge, only a few cases of preoperative CT diagnosis of Winslow foramen hernia have been described in the past. None had the above-mentioned CT findings.
Archive | 1987
B. Tarquini; Paolo Lombardi; Luigi Maria Pernice; Francesco Andreoli
Among the tools required for a future clinical chronobiology, the instrumentation described here represents only the hardware that has to be complemented with appropriate software for as-one-goes analysis of variables such as gastric acidity. The software is available to determine reference standards against which excess or deficit in gastric acidity or any other pertinent variable can be assessed chronobiologically (Cornelissen et al., 1985; Halberg et al., 1985). This is the more important since several signs and symptoms of diseases related to gastric acid secretory function show prominent circadian, ultradian and infradian variations (Tarquini, 1980). The chronobiological assessment of endoluminal gastric pH, therefore, seems most appropriate to define physiopathological aspects and schedule a proper therapy of these diseases.
Diseases of The Colon & Rectum | 2002
Springer-Verlag; Luigi Maria Pernice
Journal of Gastrointestinal Surgery | 2009
Luigi Maria Pernice; Francesco Andreoli
Diseases of The Colon & Rectum | 1986
Francesco Andreoli; Filippo Balloni; Alfio Bigiotti; Paolo Lombardi; Luigi Maria Pernice; Oscar Ronchi; Francesco Taruffi
Tumori | 2002
Desiree Pantalone; Gian Carlo Muscas; Tobias Tings; Roberto Paolucci; Maria Nincheri-Kunz; Alessandro Borri; Francesco Taruffi; Luigi Maria Pernice; Pietro Liguori; Francesco Andreoli
Archive | 1983
Pierluigi Romagnoli; Paolo Lombardi; Luigi Maria Pernice; Francesco Andreoli
115 Congresso della Società Italiana di Chirurgia | 2013
Samantha Vellei; Alessandro Borri; Luigi Maria Pernice