Luiz Arthur Barbosa Da Silva

Epidemiological profile of oral squamous cell carcinoma in a Northeastern Brazilian state

Financial support: None. Conflicts of interest: No conflicts of interest declared concerning the publication of this article. Submitted: September 27, 2017. Accepted: May 10, 2018. The study was carried out at Faculdade de Odontologia, Universidade Federal de Alagoas (UFAL), Maceió, AL, Brasil. abstract Introduction: Oral squamous cell carcinoma (OSCC) is considered the 6th most frequent worldwide type of cancer. Epidemiological surveys of cancer are important to understand how its distribution occurs in population, to create public policy of prevention and improvement of reference centers for treatment of this disease. Objective: To analyze the OSCC prevalence in Alagoas and draw the patients’ clinical profile providing guiding data to health professionals according to profile of the lesion. Materials and Methods: A retrospective analysis of 341 medical charts of patients diagnosed with OSCC was performed at reference hospital for cancer treatment in Alagoas. Results: Out of 341 patients analyzed, 217 (63.6%) were men and 124 (36.4%) were women. The mean age for men was 59.86 years and 63.16 years for women. There was a predominance of individuals who did not complete the elementary school (62.8%). The tongue was the most affected by OSCC. The majority of lesion was in clinical stage III. So, the first therapeutic scheme of choice was the association of radiotherapy and chemotherapy. Conclusion: Low educational level and poor socioeconomic development rates show that individuals affected by OSCC are probably more vulnerable to etiological agents often related to its occurrence.

CANALICULAR ADENOMA OF THE UPPER LIP: A CASE REPORT

Objective: Canalicular adenoma is a relatively rare benign tumor of the salivary glands, found almost exclusively in the minor salivary glands of the upper lip. We report a case of canalicular adenoma in the upper labial mucosa of a male patient, highlighting the clinical and histopathological differential peculiarities compared to other lesions of similar location. The immunohistochemistry was considered decisive for diagnosis confirmation and differentiation from lesions that may have similar histological characteristics. Case Description: A 68-year-old melanoderm male patient sought dental care for an asymptomatic lesion in the upper lip, measuring 7 mm, with 1 year of evolution. Excisional biopsy, microscopic evaluation, and immunohistochemical assays were performed using antibodies against CK7, S-100, and vimentin antigens. The final diagnosis of canalicular adenoma was established through the consolidation of clinical, histological, and immunohistochemical data, taking into account the differential diagnosis of this lesion. After 1 year, the patient had no recurrences. Conclusion: Immunohistochemistry was a definitive tool for the final diagnosis, ruling out the possibility of other lesions with similar morphology.