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Dive into the research topics where Lukas Weiser is active.

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Featured researches published by Lukas Weiser.


Injury-international Journal of The Care of The Injured | 2016

High incidence of osteochondral lesions after open reduction and internal fixation of displaced ankle fractures: Medium-term follow-up of 100 cases.

Marc Regier; Jan Philipp Petersen; Ahmet Hamurcu; Eik Vettorazzi; Cyrus Behzadi; Michael Hoffmann; Lars G. Großterlinden; Florian Fensky; Till Orla Klatte; Lukas Weiser; Johannes M. Rueger; Alexander S. Spiro

BACKGROUND The incidence of osteochondral lesions (OCLs) in association with displaced ankle fractures has only been examined in two previous studies. In both studies magnetic resonance imaging (MRI) was performed prior to open reduction and internal fixation (ORIF). Because MRI may overdiagnose or overestimate the extent of OCLs in an acute trauma setting the aim of this study was to determine the incidence of OCLs after ORIF of displaced ankle fractures using MRI at medium-term follow-up, and to analyse if the severity of fracture or the clinical outcome correlates with the incidence of OCLs. PATIENTS AND METHODS Following institutional review board approval a total of 100 patients (mean age, 41.3 years; range, 17.9-64.3 years) with a displaced ankle fracture who had undergone ORIF according to the AO principles were included in this study. The American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score was used to quantify the clinical outcome and MR images were evaluated for OCLs of the talus and distal tibia after a mean of 34.5 months (range, 17.5-54.1 months). RESULTS OCLs were found in 40.4% of the patients. Logistic regression revealed a significant correlation between the severity of fracture and the incidence of OCLs. Patients with a trimalleolar fracture (p=0.04) or an ankle fracture dislocation (p=0.003) had a significantly higher risk for developing an OCL compared to those with a type B fracture. Logistic regression also demonstrated a significant correlation between the clinical outcome (AOFAS score) and the incidence of OCLs (p=0.01). The risk for developing an OCL increases up to 5.6% when the AOFAS score decreases by one point. CONCLUSION OCLs were frequently found in association with acute ankle fractures at medium-term follow-up, and the severity of fracture was associated with an increased number of OCLs. Considering the disadvantages of MRI including the high cost and limited availability, the results of this study may help to explain why anatomic surgical realignment of displaced ankle fractures may still be associated with poor clinical outcomes.


Journal of Bone and Joint Surgery-british Volume | 2014

The role of inter-prosthetic distance, cortical thickness and bone mineral density in the development of inter-prosthetic fractures of the femur

Lukas Weiser; M. A. Korecki; Kay Sellenschloh; Florian Fensky; Klaus Püschel; Michael M. Morlock; Johannes M. Rueger; Wolfgang Lehmann

It is becoming increasingly common for a patient to have ipsilateral hip and knee replacements. The inter-prosthetic (IP) distance, the distance between the tips of hip and knee prostheses, has been thought to be associated with an increased risk of IP fracture. Small gap distances are generally assumed to act as stress risers, although there is no real biomechanical evidence to support this. The purpose of this study was to evaluate the influence of IP distance, cortical thickness and bone mineral density on the likelihood of an IP femoral fracture. A total of 18 human femur specimens were randomised into three groups by bone density and cortical thickness. For each group, a defined IP distance of 35 mm, 80 mm or 160 mm was created by choosing the appropriate lengths of component. The maximum fracture strength was determined using a four-point bending test. The fracture force of all three groups was similar (p = 0.498). There was a highly significant correlation between the cortical area and the fracture strength (r = 0.804, p < 0.001), whereas bone density showed no influence. This study suggests that the IP distance has little influence on fracture strength in IP femoral fractures: the thickness of the cortex seems to be the decisive factor.


Journal of Bone and Joint Surgery-british Volume | 2016

Cement augmentation versus extended dorsal instrumentation in the treatment of osteoporotic vertebral fractures: a biomechanical comparison

Lukas Weiser; M Dreimann; Gerd Huber; Kay Sellenschloh; K. Püschel; Michael M. Morlock; Johannes M. Rueger; Wolfgang Lehmann

AIMS Loosening of pedicle screws is a major complication of posterior spinal stabilisation, especially in the osteoporotic spine. Our aim was to evaluate the effect of cement augmentation compared with extended dorsal instrumentation on the stability of posterior spinal fixation. MATERIALS AND METHODS A total of 12 osteoporotic human cadaveric spines (T11-L3) were randomised by bone mineral density into two groups and instrumented with pedicle screws: group I (SHORT) separated T12 or L2 and group II (EXTENDED) specimen consisting of T11/12 to L2/3. Screws were augmented with cement unilaterally in each vertebra. Fatigue testing was performed using a cranial-caudal sinusoidal, cyclic (1.0 Hz) load with stepwise increasing peak force. RESULTS Augmentation showed no significant increase in the mean cycles to failure and fatigue force (SHORT p = 0.067; EXTENDED p = 0.239). Extending the instrumentation resulted in a significantly increased number of cycles to failure and a significantly higher fatigue force compared with the SHORT instrumentation (EXTENDED non-augmented + 76%, p < 0.001; EXTENDED augmented + 87%, p < 0.001). CONCLUSION The stabilising effect of cement augmentation of pedicle screws might not be as beneficial as expected from biomechanical pull-out tests. Lengthening the dorsal instrumentation results in a much higher increase of stability during fatigue testing in the osteoporotic spine compared with cement augmentation. Cite this article: Bone Joint J 2016;98-B:1099-1105.


Unfallchirurg | 2017

Modifizierte Goel-Harms-Technik mit C1-Pedikelschrauben

Lennart Viezens; Lukas Weiser; Wolfgang Lehmann

Abb. 18 a,bPäoperative axiale undsagittaleDarstellungdesC1-Wirbelbogensmitausreichendweitem Pedikel. c,d Postoperative axiale und sagittale Darstellung des C1-Wirbelbogensmit liegender Pedikelschraube In unserer klinischen Erfahrung hat sichdiemodifizierteC1-Instrumentation mit Pedikelschrauben bewehrt und wird von uns in allen Fällen angewendet, in denen der Durchmesser des C1-Bogens groß genug ist, um eine Pedikelschraube aufzunehmen. Die präoperative Planung muss neben der von den Kollegen beschrieben Planung der Trajektorie der Schraube und des Verlaufs der A. vertebralis um denDurchmesserdesC1-Bogens ergänzt werden (. Abb. 1). Wennder Bogen einen ausreichenden DurchmesserhatkannderEintrittspunkt wie von den Kollegen beschrieben mit


Journal of Bone and Joint Surgery-british Volume | 2016

Cement augmentation versus extendeddorsal instrumentation in the treatment of osteoporotic vertebralfractures

Lukas Weiser; M. Dreimann; Gerd Huber; Kay Sellenschloh; K. Püschel; Michael M. Morlock; Johannes M. Rueger; Wolfgang Lehmann

AIMS Loosening of pedicle screws is a major complication of posterior spinal stabilisation, especially in the osteoporotic spine. Our aim was to evaluate the effect of cement augmentation compared with extended dorsal instrumentation on the stability of posterior spinal fixation. MATERIALS AND METHODS A total of 12 osteoporotic human cadaveric spines (T11-L3) were randomised by bone mineral density into two groups and instrumented with pedicle screws: group I (SHORT) separated T12 or L2 and group II (EXTENDED) specimen consisting of T11/12 to L2/3. Screws were augmented with cement unilaterally in each vertebra. Fatigue testing was performed using a cranial-caudal sinusoidal, cyclic (1.0 Hz) load with stepwise increasing peak force. RESULTS Augmentation showed no significant increase in the mean cycles to failure and fatigue force (SHORT p = 0.067; EXTENDED p = 0.239). Extending the instrumentation resulted in a significantly increased number of cycles to failure and a significantly higher fatigue force compared with the SHORT instrumentation (EXTENDED non-augmented + 76%, p < 0.001; EXTENDED augmented + 87%, p < 0.001). CONCLUSION The stabilising effect of cement augmentation of pedicle screws might not be as beneficial as expected from biomechanical pull-out tests. Lengthening the dorsal instrumentation results in a much higher increase of stability during fatigue testing in the osteoporotic spine compared with cement augmentation. Cite this article: Bone Joint J 2016;98-B:1099-1105.


Journal of Bone and Joint Surgery-british Volume | 2016

Cement augmentation versus extended dorsal instrumentation in the treatment of osteoporotic vertebral fractures

Lukas Weiser; M. Dreimann; Gerd Huber; Kay Sellenschloh; K. Püschel; Michael M. Morlock; Johannes M. Rueger; Wolfgang Lehmann

AIMS Loosening of pedicle screws is a major complication of posterior spinal stabilisation, especially in the osteoporotic spine. Our aim was to evaluate the effect of cement augmentation compared with extended dorsal instrumentation on the stability of posterior spinal fixation. MATERIALS AND METHODS A total of 12 osteoporotic human cadaveric spines (T11-L3) were randomised by bone mineral density into two groups and instrumented with pedicle screws: group I (SHORT) separated T12 or L2 and group II (EXTENDED) specimen consisting of T11/12 to L2/3. Screws were augmented with cement unilaterally in each vertebra. Fatigue testing was performed using a cranial-caudal sinusoidal, cyclic (1.0 Hz) load with stepwise increasing peak force. RESULTS Augmentation showed no significant increase in the mean cycles to failure and fatigue force (SHORT p = 0.067; EXTENDED p = 0.239). Extending the instrumentation resulted in a significantly increased number of cycles to failure and a significantly higher fatigue force compared with the SHORT instrumentation (EXTENDED non-augmented + 76%, p < 0.001; EXTENDED augmented + 87%, p < 0.001). CONCLUSION The stabilising effect of cement augmentation of pedicle screws might not be as beneficial as expected from biomechanical pull-out tests. Lengthening the dorsal instrumentation results in a much higher increase of stability during fatigue testing in the osteoporotic spine compared with cement augmentation. Cite this article: Bone Joint J 2016;98-B:1099-1105.


Journal of Bone and Joint Surgery-british Volume | 2016

Cement augmentation versus extendeddorsal instrumentation in the treatment of osteoporotic vertebralfractures: a biomechanical comparison

Lukas Weiser; M. Dreimann; Gerd Huber; Kay Sellenschloh; K. Püschel; Michael M. Morlock; Johannes M. Rueger; Wolfgang Lehmann

AIMS Loosening of pedicle screws is a major complication of posterior spinal stabilisation, especially in the osteoporotic spine. Our aim was to evaluate the effect of cement augmentation compared with extended dorsal instrumentation on the stability of posterior spinal fixation. MATERIALS AND METHODS A total of 12 osteoporotic human cadaveric spines (T11-L3) were randomised by bone mineral density into two groups and instrumented with pedicle screws: group I (SHORT) separated T12 or L2 and group II (EXTENDED) specimen consisting of T11/12 to L2/3. Screws were augmented with cement unilaterally in each vertebra. Fatigue testing was performed using a cranial-caudal sinusoidal, cyclic (1.0 Hz) load with stepwise increasing peak force. RESULTS Augmentation showed no significant increase in the mean cycles to failure and fatigue force (SHORT p = 0.067; EXTENDED p = 0.239). Extending the instrumentation resulted in a significantly increased number of cycles to failure and a significantly higher fatigue force compared with the SHORT instrumentation (EXTENDED non-augmented + 76%, p < 0.001; EXTENDED augmented + 87%, p < 0.001). CONCLUSION The stabilising effect of cement augmentation of pedicle screws might not be as beneficial as expected from biomechanical pull-out tests. Lengthening the dorsal instrumentation results in a much higher increase of stability during fatigue testing in the osteoporotic spine compared with cement augmentation. Cite this article: Bone Joint J 2016;98-B:1099-1105.


Archives of Orthopaedic and Trauma Surgery | 2015

Extra- vs. intramedullary treatment of pertrochanteric fractures: a biomechanical in vitro study comparing dynamic hip screw and intramedullary nail

Lukas Weiser; Andreas A. Ruppel; Jakob V. Nüchtern; Kay Sellenschloh; Johannes Zeichen; Klaus Püschel; Michael M. Morlock; Wolfgang Lehmann


European Spine Journal | 2017

Insufficient stability of pedicle screws in osteoporotic vertebrae: biomechanical correlation of bone mineral density and pedicle screw fixation strength

Lukas Weiser; Gerd Huber; Kay Sellenschloh; Lennart Viezens; Klaus Püschel; Michael M. Morlock; Wolfgang Lehmann


Knee Surgery, Sports Traumatology, Arthroscopy | 2017

Acromioclavicular joint dislocations: coracoclavicular reconstruction with and without additional direct acromioclavicular repair

Lukas Weiser; Jakob V. Nüchtern; Kay Sellenschloh; Klaus Püschel; Michael M. Morlock; Johannes M. Rueger; Michael Hoffmann; Wolfgang Lehmann; Lars G. Großterlinden

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Kay Sellenschloh

Hamburg University of Technology

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Michael M. Morlock

Hamburg University of Technology

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Gerd Huber

Hamburg University of Technology

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