Lyndsay Fraser
Royal Hospital for Sick Children
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Lyndsay Fraser.
Otolaryngology-Head and Neck Surgery | 2008
Lyndsay Fraser; Phillip L Moore; Haytham Kubba
OBJECTIVE: We review the management of 31 cases of atypical mycobacterial lymphadenitis presenting to a tertiary referral pediatric otolaryngology department between February 2002 and February 2007. STUDY DESIGN: Retrospective case review. SUBJECTS AND METHODS: Cases were identified by using the hospitals correspondence and pathology databases. Demographic and clinical information was collected. Descriptive and nonparametric inferential statistics (SPSS; SPSS Inc, Chicago, IL) were calculated. RESULTS: Four patients were treated conservatively with triple-therapy antibiotics. Twenty-seven underwent surgical excision plus 3 months of clarithromycin postoperatively. Thirteen percent developed nodal recurrence; this appeared to be unrelated to the operation performed (χ8 2 = 5.8, P = 0.69) or the management modality used (P = 0.35). Patients with previous surgery were more likely to have recurrent infection (χ2 2 = 9.3, P = 0.01). CONCLUSIONS: In our experience, nodal excision plus postoperative clarithromycin remains the best treatment option for most children, although those with limited disease may benefit from combination antibiotic therapy. Previous incision and drainage leads to high recurrence rates after later excision and therefore, heightened awareness of these infections is essential to ensure appropriate early management.
Otolaryngology-Head and Neck Surgery | 2008
Andrew D. Whymark; David P. Crampsey; Lyndsay Fraser; Philip Moore; Craig Williams; Haytham Kubba
OBJECTIVE: Epistaxis is very common in children but its cause remains unknown. We postulate that nasal colonization with Staphylococcus aureus leads to inflammation, crusting, and ultimately new vessel formation. STUDY DESIGN: A prospective case-control study. SUBJECTS AND METHODS: Sixty-seven children were recruited, 42 with epistaxis (22 had crusting in the nasal vestibule; 20 did not) and 25 control subjects. A microbiology swab was taken from the anterior nasal cavity of each child. RESULTS: All groups were equally likely to have a positive culture. S aureus was more common in the epistaxis group (P = 0.008) compared with the control group. There was no difference in the prevalence of S aureus between crust and noncrust groups. Epistaxis patients were much less likely to have isolates of respiratory pathogens or a skin commensal. CONCLUSION: Children with epistaxis are more likely to have nasal colonization with S aureus than controls. Our data would support the hypothesis that S aureus replaces existing nasal flora and causes inflammation and new vessel formation.
Otolaryngology-Head and Neck Surgery | 2009
Nicholas Calder; Swee K. Kang; Lyndsay Fraser; Tash Kunanandam; Jennifer Montgomery; Haytham Kubba
Background: To establish whether a treatment regimen of silver nitrate cautery and 4 weeks of antiseptic nasal cream is superior to antiseptic cream treatment alone in the management of pediatric epistaxis. Study Design: Double-blind randomized controlled trial. Subjects and Methods: Children with epistaxis and visible anterior septal vessels were invited to participate. Patients were randomized to receive treatment or control. Treatment patients received silver nitrate cautery, followed by antiseptic cream for 4 weeks. Control patients received sham cautery followed by antiseptic cream for 4 weeks. Results: A total of 109 patients were randomized and results were available for 93 (85%). Of those receiving cautery, 21 (45.7%) of 46 had no bleeding in the 4 weeks before follow-up. Of those receiving only antiseptic cream 14 (29.8%) of 47 had no bleeding. (χ2 = 2.49; P = 0.114). More children in the active treatment group had an improvement in their symptoms compared with controls (42 of 46; 91.3%) in the treatment group vs 33 of 47 (70.2%) controls (χ2 = 6.626; P = 0.01; relative risk reduction = 71 percent, number needed to treat = 4.7). Conclusion: When using subjective improvement in symptoms as the outcome measure, silver nitrate cautery with antiseptic cream twice daily for 4 weeks appears to give a small but statistically significant benefit when compared to antiseptic cream alone.
Clinical Otolaryngology | 2016
Lyndsay Fraser; Jennifer Montgomery; H. James; David McGregor Wynne; F.B. MacGregor; W.A. Clement; M.S.C. Morrissey; Haytham Kubba
Comparison of pinnaplasty techniques is difficult due to variation in the reporting of outcomes. We aimed to develop a family‐centred outcome questionnaire for use after pinnaplasty and assess it for reliability and validity.
International Journal of Pediatric Otorhinolaryngology | 2013
Lyndsay Fraser; Katie O’Neill; Richard Locke; Morag Attaie; Greg J. Irwin; Haytham Kubba; Fiona MacGregor
OBJECTIVES Cervical lymphadenopathy is common in children and can arise from a wide range of aetiologies. Ultrasound can be a useful imaging tool for initial investigation but is known to be operator dependent. We aimed to compare the content of ultrasound reporting in this clinical scenario before and after the introduction of an evidence-based reporting protocol. METHODS We performed a prospective 8-month pilot study assessing the content of ultrasound reports generated from scans to investigate suspected cervical lymphadenopathy in children referred to our tertiary referral otolaryngology service. We found wide variation in report content and inconsistent reporting of certain radiological features. In response to this we performed a literature search to identify key, clinically relevant ultrasonographic features for cervical lymphadenopathy and then in consultation with our radiology colleagues, devised a protocol to facilitate the reporting of these key features. Content of reports was then prospectively re-audited over a further 8-month period. RESULTS 23 reports were assessed before and 26 after introduction of the reporting protocol. Fishers exact test was used to analyse the data. We found a statistically significant (p < 0.05) improvement in the frequency of reporting of various key features such as nodal distribution, shape, echogenicity, calcification, necrosis and vascular pattern. CONCLUSIONS The introduction of a standardised protocol has helped to streamline the reporting of ultrasounds to investigate cervical lymphadenopathy within our department. In the absence of any national guidelines on the reporting of paediatric neck ultrasound in this scenario, we propose that our protocol could be used by other departments to improve standardisation and as a teaching aid.
International Journal of Pediatric Otorhinolaryngology | 2013
Lyndsay Fraser; Nicola Starritt; Louise Melia; Haytham Kubba
OBJECTIVES Early splinting of neonatal ear deformities has been proven to be successful but the opportunity to splint is frequently missed due to lack of awareness amongst healthcare personnel. We aimed to develop a regional screening service using neonatal hearing screeners and an information leaflet to allow for the early detection and treatment of such children. METHODS We created an information leaflet that was distributed by hearing screeners to all parents in Greater Glasgow at the time of the childs neonatal hearing assessment, with a contact number allowing parents to self refer. All neonates referred were seen at a dedicated clinic within a week and suitability for splints determined. We aimed to assess acceptability of the service, splinting result as rated by parents and otolaryngologist and also costs involved. RESULTS Over a 15 month period, 13,403 leaflets were distributed. 88 babies were referred (0.7%) and 54 were found suitable for splinting. 78% of parents rated the efficacy of splints as either excellent or very good and 96% said they would recommend the service to a friend. Median age at first review was 4 days. We found a weak but statistically significant correlation between age at first review and the surgeon rated outcome from splinting (Spearmans rho=-0.321, p=0.038), with those babies commencing treatment early generally having a better splinting result. We also found that age at first review correlated with duration of splinting required (Spearmans rho=0.357, p=0.008), with younger babies generally requiring shorter splinting times. Cost analysis revealed a saving of £482.76 per child when comparing splint treatment to potential later corrective ear surgery costs. CONCLUSIONS Our screening service is both acceptable to parents and efficient in allowing for early correction of ear deformity in the majority of cases. By detecting treatable children early, we propose that the introduction of routine screening and splinting on a wider basis will avoid the psychological burden of ear deformity in childhood and also avoid the need for later corrective surgery.
Clinical Otolaryngology | 2017
Lyndsay Fraser; Jennifer Montgomery; Lisa Murphy; Harry James; Haytham Kubba
Tos (CHAT) technique in cholesteatoma surgery: surgical technique and preliminary results. J. Laryngol. Otol. 119, 429–435 3 Vincent R., Oates J., Sperling N.M. et al. (2004) Malleus relocation in ossicular reconstruction: managing the anteriorly positioned malleus: results in a series of 268 cases. Otol. Neurotol. 25, 223–230 4 Kartush J.M. (1994) Ossicular chain reconstruction. Capitulum to malleus. Otolaryngol. Clin. North Am. 27, 689–715 5 Committee on Hearing and Equilibrium guidelines for the evaluation of results of treatment of conductive hearing loss. Americanacademy of Otolaryngology-Head and Neck Surgery Foundation I. (1995) Otolaryngol. Head Neck Surg. 113,186–187 6 De Vos C., Gersdorff M. & Gerard J.M. (2007) Prognostic factors in ossiculoplasty. Otol. Neurotol. 28, 61–67 7 Ghonim M.R., Shabana Y.K., Ashraf B. et al. (2016) Traumatic ossicular disruption with intact tympanic membrane: treatment modalities in 42 patients. Clin. Otolaryngol. 41, 176–179 8 Ghonim M.R., Shabana Y.K. & Elkotb M.Y. (2011) Outcome of malleo-stapedotomy using the malleus relocation technique during revision stapes surgery. J. Laryngol. Otol. 125, 441–444 9 Gaillardin L., Lescanne E., Moriniere S. et al. (2012) Residual cholesteatoma: prevalence and location. Follow-up strategy in adults. Eur. Ann. Otorhinolaryngol. Head Neck Dis. 129, 136–140 10 East D. (1997) The use of conchal cartilage in the closure of small epitympanic defects. In Cholesteatoma and Ear Surgery, Sanna M. (ed), pp 579–582. CIC Edizioni Internazionali, Roma 11 Marchioni D., Mattioli F., Alicandri-Ciufelli M. et al. (2010) Endoscopic evaluation of middle ear ventilation route blockage. Am. J. Otolaryngol. 31, 453–466
Otolaryngology-Head and Neck Surgery | 2007
Amelia F. Drake; Albert H. Park; David P. Crampsey; Lyndsay Fraser; Andrew D. Whymark; Phillip L Moore; Craig Williams; Haytham Kubba
missions were Ohio (15%), California (13%), and Illinois (7%); these three states did not have the highest spending per admission. Indicators for high resource utilization included length of stay (mean, 11.5 days; OR 1.09), number of procedures performed (mean, 3.4; OR 1.27), underlying diagnosis (OR 1.42), female gender (OR 1.42), and discharge quarter (OR 27.2). Median total charges for an admission were
Otolaryngology-Head and Neck Surgery | 2007
Sukgi S. Choi; Albert H. Park; Lyndsay Fraser; Phillip L Moore; Haytham Kubba
20,518; 90% of patients had total charges less than
Archives of Disease in Childhood | 2012
Lyndsay Fraser; David M. Wynne; W. Andrew Clement; Mark Davidson; Haytham Kubba
139,253. CONCLUSIONS: Analysis of the KID allows for assessment of national trends and resource utilization in pediatric diseases. For SGS, median charges for an admission were