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Featured researches published by M.A. Batata.


The Journal of Urology | 1977

Radical Cystectomy with or Without Prior Irradiation in the Treatment of Bladder Cancer

Willet F. Whitmore; M.A. Batata; Mohamed A. Ghoneim; Harry Grabstald; A. Unal

This is a summary presentation on certain aspects of an experience with the use of radical cystectomy with or without prior irradiation in the treatment of selected patients with bladder cancer at the Memorial Sloan-Kettering Cancer Center.


Cancer | 1974

Thymomas: Clinicopathologic features, therapy, and prognosis

M.A. Batata; Nael Martini; Andrew G. Huvos; Rafael I. Aguilar; Edward J. Beattie

Fifty‐four patients with thymoma were seen at Memorial Hospital from 1928 to 1972. There were 18 benign and 36 malignant thymomas. Benign tumors were completely encapsulated. Malignant tumors were non‐encapsulated or incompletely encapsulated and invasive. All patients with benign thymoma were treated by resection alone. None had recurrent disease or died with tumor for periods ranging from 5 to 17 years after resection. Patients with malignant thymoma treated by resection alone had recurrent tumor within 5 years and subsequently died of their disease. All malignant thymoma patients who were alive free of disease for 5 or more years had radiation therapy and resection. Clinicopathologic features indicating a poor prognosis were: a non‐encapsulated tumor of a predominantly epithelial cell type, superior vena caval syndrome, malignant pleural effusion, supraclavicular lymph node involvement, dysphagia, hoarseness, myasthenia gravis, erythroid hypoplasia, and hypogammaglobulinemia.


Cancer | 1982

Recovery from aspermia induced by low-dose radiation in seminoma patients

E. W. Hahn; S. M. Feingold; Larry Simpson; M.A. Batata

Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para‐aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectomy scar. The incidental amount of radiation to the remaining testicle averaged 78.4 ± 7.4 rad and ranged from 32–178 rad as determined by thermoluminescent dosimetry. Induction of aspermia was documented in ten out of 14 patients who received over 65 rad to the gonad. At lower doses, aspermia may not have occurred or was of short duration. Recovery of sperm in the semen occurred in 12 patients within 30–80 weeks after start of treatment. The data suggest that the time of recovery may be dose dependent within the range of 19–148 rad. During the period of recovery, patients with oligospermic semen may be fertile and should be so advised.


Cancer | 1975

Primary carcinoma of the ureter: A prognostic study

M.A. Batata; Willet F. Whitmore; Basil S. Hilaris; Nobuhiko Tokita; Harry Grabstald

Forty‐one patients with primary invasive carcinomas of the ureter were seen at Memorial Hospital from 1947 to 1972. Overall survival patterns were similar in 19 patients with and 22 patients without prior or concomitant urothelial cancers elsewhere in the urinary tract, with 5‐year survival rates, as estimated by the product‐limit method, of 41% for both groups. Prognosis was determined primarily by anatomical stage of ureteral cancer. In 11 Stage A (submucosal) patients, 7 Stage B (muscular), 12 Stage C (periureteric fat), and 9 Stage D (extraureteral), the similarly estimated 5‐year survival rates were 91%, 43%, 23%, and nil, respectively. None of Stage A cases had metastases for periods ranging from 5 to 11 years after surgery alone. Seventy‐eight percent of patients with more advanced stages died within 3 years of treatment, with metastases mainly in pelvic and para‐aortic lymph nodes.


The Journal of Urology | 1980

Cryptorchidism and Testicular Cancer

M.A. Batata; Willet F. Whitmore; F.C.H. Chu; Basil S. Hilaris; J. Loh; Harry Grabstald; Robert B. Golbey

An analysis of 125 patients with a history or clinical evidence of cryptorchidism and testicular germinal tumor treated at our hospital from 1934 to 1975 is presented. Cryptorchidism was corrected ipsilaterally or contralaterally in 83 patients with intrascrotal testis cancer when they were from 4 to 42 years old, either spontaneously (21 patients), by orchiopexy (51 patients) or by hormonal therapy (11 patients). Forty-two cryptorchid patients (uncorrected cases) presented with either ipsilateral inguinal (24 patients), abdominal (14 patients) or contralateral intrascrotal tumors (4 patients). Tumor histologic types on orchiectomy were pure seminoma in 54 patients, embryonal carcinoma in 35, teratocarcinoma in 33 and pure choriocarcinoma in 3. The 5-year survival rates were 60 per cent for the corrected cases and 63 per cent for the uncorrected cases according to cryptorchid state, and they were 78 per cent in patients with pure seminoma and 48 per cent in patients with other germinomas according to histologic type. The majority (58 of 73) of 5-year survivors received regional lymphatic irradiation, in 39 patients with pure seminoma, and/or systemic chemotherapy, in 19 patients with germinal carcinomas, with or without regional lymphadenectomy.


Cancer | 1977

A comparative study of two preoperative radiation regimens with cystectomy for bladder cancer

Willet F. Whitmore; M.A. Batata; Basil S. Hilaris; G. N. Reddy; A. Unal; Mohamed A. Ghoneim; Harry Grabstald; F.C.H. Chu

This report surveys the results of two programs of preoperative irradiation with radical cystectomy for bladder cancer in 205 patients. Irradiating the true pelvis to 4000 rads in 4 weeks with radical cystectomy after 6 weeks was implemented in 119 patients (Group 1) from 1959 to 1965; 2000 rads given in 1 week to the true pelvis and radical cystectomy within the following week was implemented in 86 patients (Group 2) from 1966 to 1970. Determinate survival without evidence of recurrence at 5 years was 43% in Group 1 and 42% in Group 2. Mortality with recurrence of bladder cancer in 5 or more years was 44% in group 1 and 42% in group 2. Pelvic complications occurred in 13% of group 1 and 9% of group 2.


Cancer | 1982

Testicular cancer in cryptorchids.

M.A. Batata; Florence C. H. Chu; Basil S. Hilaris; Willet F. Whitmore; Robert B. Golbey

One‐hundred thirty‐seven patients with a history or clinical evidence of cryptorchidism and testicular germinal tumor were treated at our hospital from 1934 to 1976. Cryptorchidism was corrected ipsilaterally or contralaterally in 93 patients with intrascrotal testis cancer when they were from 2 to 42 years old, either spontaneously (24 patients), by orchiopexy (58 patients), or by hormonal therapy (11 patients). Forty‐four cryptorchid patients (uncorrected cases) had either ipsilateral inguinal (24 patients), or abdominal (14 patients), or contralateral intrascrotal tumors (six patients). Tumor histologic types on orchiectomy were pure seminoma in 56 patients, embryonal carcinoma in 41, teratocarcinoma in 37, and pure choriocarcinoma in 3.


International Journal of Radiation Oncology Biology Physics | 1977

Behavioral patterns of prostate adenocarcinoma following an 125I implant and pelvic node dissection

Basil S. Hilaris; Willet F. Whitmore; M.A. Batata; Winston E. Barzell

Abstract This study is based on 208 patients with adenocarcinoma of the prostate, treated between February 1970 and September 1976 with a combined technique of retropubic bilateral pelvic lymphadenectomy and interstitial implantation of the prostate with 125 I sources. All patients were classified according to the criteria proposed by Willet Whitmore 13 and the UICC (International Union Against Cancer) 11 clinical staging. 128 patients were clinically stage B ( T 1 : 65, T 2 : 40 and T 3 : 23) and 80 patients were clinically stage C ( T 4 ). The patients were analyzed for clinicopathological behavioral patterns according to age, tumor extent, size, location and grade. These variables also were correlated with mode of initial nodal involvement, subsequent recurrence, and corresponding survival patterns. Analysis of this material points to a high overall frequency of lymph node metastases (40%), varying according to the size and extent of the primary tumor. The incidence of positive nodes relative to clinical stage B is 29% ( T 2 : 9%, T 2 : 40%, T 3 : 65%) and clinical stage C ( T 4 ) 59%. The association of the initial lymph node status with the subsequent development of distant metastases allows the identification of three major groups of patients in terms of survival and probability of distant cancer spread. The first group consists of patients with disease limited to the prostate having negative regional nodes. The second group consists of patients having either extra-prostatic extension with negative nodes or smaller prostatic tumors with positive nodes. The third group includes those patients with large prostatic tumors with or without extra-prostatic extension and positive nodes.


Urology | 1982

125I implantation for carcinoma of prostate Further follow-up of first 100 cases

H.B. Grossman; M.A. Batata; Basil S. Hilaris; Willet F. Whitmore

Analysis of the first 100 patients at the Memorial Sloan-Kettering Cancer Center with Stage B or C prostatic cancer treated by pelvic lymph node dissection and Iodine-125 implantation and endocrine therapy when specifically indicated revealed five-year survival rates of 87 and 77 per cent, respectively. Tumor stage, tumor grade, and lymph node metastasis each correlated with survival, but the latter was the most significant factor. Although routine follow-up biopsies were not performed, local tumor control as judged by serial digital rectal examination defined a prognostically favored group of patients. In the absence of controls, however, whether the latter response indicates a salutary effect of the treatment which produces an improved survival or merely identifies a group of patients who were predetermined to have a more favorable survival is undetermined.


Cancer | 1982

Preoperative irradiation and cystectomy for bladder cancer

Joseph A. Smith; M.A. Batata; Harry Grabstald; Pramod C. Sogani; Harry W. Herr; Willet F. Whitmore

Between 1971 and 1974, 101 patients at Memorial Sloan‐Kettering Cancer Center underwent planned integrated treatment for bladder cancer with 2000 rads by megavoltage delivered to the whole pelvis over five consecutive days followed by radical cystectomy within a week. The overall five‐year survival rate was 39%; the hospital mortality rate was 2%. In the pelvis alone tumor recurred in 9% of the patients. These results support other studies demonstrating the efficacy of this and other regimens of preoperative irradiation and cystectomy.

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Willet F. Whitmore

Memorial Sloan Kettering Cancer Center

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Basil S. Hilaris

Memorial Sloan Kettering Cancer Center

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F.C.H. Chu

Memorial Sloan Kettering Cancer Center

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Harry Grabstald

Memorial Sloan Kettering Cancer Center

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Robert B. Golbey

Memorial Sloan Kettering Cancer Center

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Edward J. Beattie

University of Illinois at Chicago

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Harry W. Herr

Memorial Sloan Kettering Cancer Center

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Nael Martini

Memorial Sloan Kettering Cancer Center

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Y.S. Kim

Memorial Sloan Kettering Cancer Center

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M.Z. Lee

Memorial Sloan Kettering Cancer Center

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