M.A. van't Hof

Bite Forces with Mandibular Implant-retained Overdentures

Sensitivity or pain of the mucoperiosteum covering the mandibular edentulous ridge is often thought to limit bite forces in complete-denture wearers. Therefore, bite forces with mandibular implant-retained overdentures may depend on the degree of implant support. This study analyzed the effects of different degrees of support for the mandibular denture on bite forces measured four years after denture treatment as part of a randomized controlled clinical trial. All subjects had received new maxillary dentures and (1) mainly implant-borne overdentures on a transmandibular implant (TMI), (2) mucosa-borne overdentures on two cylindric permucosal IMZ implants, or (3) new conventional dentures in the mandible. Fifty-three women and 15 men (mean age, 59.1 yrs; range, 41 to 77) participated in this trial. Both unilateral and bilateral bite forces were recorded at different positions with a miniature strain gauge transducer and a mechanical bite fork, respectively. The subjects were asked to bite at three force levels. Results indicated that women had significantly lower maximum bite forces than men. Persons with mandibular implant-retained overdentures had significantly higher unilateral and bilateral maximum bite forces than complete-denture wearers. However, bite forces did not differ between the mainly implant-borne (TMI) and mucosa-implant-borne (IMZ) implant systems. Therefore, it appears that differences in support for the mandibular overdenture by dental implants are not reflected in bite force capabilities.

Enhanced resistance to oxidation of low density lipoproteins and decreased lipid peroxide formation during beta-carotene supplementation in cystic fibrosis

We investigated the effect of correcting beta-carotene deficiency in cystic fibrosis (CF) patients on two parameters of lipid peroxidation. The resistance to oxidation of low density lipoprotein (LDL) was measured by the lag time preceding the onset of conjugated diene formation during exposure to copper(II) ions, and lipid peroxide formation was quantitated by malondialdehyde concentrations in plasma (TBA/HPLC method). Simultaneously, alpha-tocopherol and beta-carotene concentrations were determined in LDL and in plasma. Thirty-four CF patients were investigated before and after 3 months of oral beta-carotene supplementation. Beta-carotene concentrations increased (p < 0.0001) in plasma (mean +/- SD) (0.09 +/- 0.06 vs. 1.07 +/- 0.86 mumol/l) and in LDL (0.02 +/- 0.02 vs. 0.31 +/- 0.28 mol/mol), without significant changes in alpha-tocopherol, either in plasma (24.7 +/- 5.9 vs. 25.4 +/- 7.6) or in LDL (8.47 +/- 2.95 vs. 9.05 +/- 4.13). Lag times, being shorter (p < 0.05) in patients than in controls, increased from 48.5 +/- 21.3 to 69.1 +/- 27.9 min (p < 0.001) and plasma MDA concentrations, being greater (p < 0.0001) in patients than in controls, decreased from 0.95 +/- 0.32 to 0.61 +/- 0.15 mumol/l (p < 0.0001). At 3 months, lag times and MDA concentrations did not any longer differ between patients and controls. These data suggest that excess lipid peroxidation occurring in beta-carotene deficiency can be limited and normalized during efficient beta-carotene supplementation in CF patients.

A Seven-and-a-half-year Survival Study of Resin-bonded Bridges

A clinical trial, concerning 203 resin-bonded bridges (RBBs), was performed for investigation of the influence of retainer-type and cementation materials on the survival of these restorations. The survival rates after a 7.5-year follow-up were 75% for anterior RBBs and 44% for posterior bridges. Etched metal RBBs (E-bridges) were significantly more retentive than perforated RBBs (P-bridges); the survival rates were 78% and 63%, respectively. With respect to the cementation materials, Clearfil F, in combination with E-bridges, had the best overall survival (89%, anterior and posterior). Maxillary anterior RBBs were more susceptible to failure than mandibular anterior RBBs.

Demand and Need for Treatment of Craniomandibular Dysfunction in the Dutch Adult Population

A nationwide survey of oral conditions, treatment needs, and attitudes toward dental health care in Dutch adults was carried out in 1986. One of the aims of the study was to investigate the perceived need and demand for treatment of craniomandibular dysfunction (CMD). A sample of 6577 persons (15-74 yrs of age), stratified for gender, age, region, and socio-economic status, was contacted. Of this sample, 4496 persons participated in the behavioral part of the study, of which 3526 were examined clinically. The CMD-treatment demand was based on (1) CMD complaints in the past, (2) CMD complaints at present, and (3) an anticipated increase of the present complaints. CMD was both anamnestically and clinically assessed, independently by different examiners. A total of 21.5% of the Dutch adult population reported dysfunction, but 85% of these perceived no need for treatment. With most of the remaining 15% either seeking or intending to seek treatment (or having had it before), a figure of 3.1% can be used to summarize the actual level of treatment need for CMD in the Dutch adult population.

Habitual dietary calcium intake and cortical bone loss in perimenopausal women: a longitudinal study.

SummaryDuring an 8-year follow-up study, the effect of habitual dietary calcium intake on cortical bone loss in 154 healthy perimenopausal women was examined. Dietary calcium intake, determined by the cross-check dietary history method, and cortical bone mineral content of the radius were measured annually. Habitual dietary calcium intake was calculated as the mean of the estimated daily dietary calcium intake during the follow-up period. The women were classified according to their habitual calcium intake: those with an intake below 800 mg/day (n=28), between 800 and 1350 mg/day (n=95), and above 1350 mg/day (n=31). The results show a continuous significant loss of cortical bone in all groups, amounting yearly to 1.3±0.25, 1.5±0.10, and 1.9±0.23% (mean±SE) for the groups with a low, medium, and high habitual calcium intake, respectively (P<0.01). The differences among the three groups did not reach statistical significance (P=0.11). Body mass index was found to be positively correlated with the negative changes in cortical bone mineral density (r=0.32,P<0.01), even after adjustments had been made for confounding factors. It is concluded that a habitual calcium intake exceeding 800 mg/day (the current Recommended Daily Allowance for adults) is ineffective in preventing cortical bone loss during early menopause. Body mass index is of major importance for the perimenopausal bone loss.

Controlled clinical study of amalgam restorations: survival, failures, and causes of failure

The survival and modes of failure of amalgam restorations were investigated retrospectively. 2660 Class I or II lesions were restored and evaluated yearly or half-yearly for failures during the 30- to 84-month follow-up. Restorations with unacceptable margins were not counted as failures if no traces of secondary caries could be seen. 8% of the restorations were lost because of patient drop-out. Of the remaining restorations, 1% was replaced due to primary caries. Of the remaining number (2431), 9% failed because of all other reasons. The leading mode of failure was bulk fracture (4.6%), followed by tooth fracture (1.9%), and marginal ridge fracture (1.3%). For all other reasons, 0.8% of the restorations failed. Only two restorations were replaced because of secondary caries. The alloy selection in both conventional and high-copper categories significantly influenced the survival of the restorations for reasons directly related to the restoration.

The convergence angle of tooth preparations for complete crowns

F actors that influence the retention of complete gold crowns may be categorized as (1) the preparation, (2) the restoration, and (3) the cement.‘” This article discusses the influence of the convergence angle of tooth preparations on the retention of an artificial crown. The convergence angle can be defined as the angle made by the opposite walls of a preparation.4 The tooth preparations for the clinical research had provided sufficient retention inasmuch as all restorations were still present after 5 years without recementing. According to Gabe15 the best retention was created by preparing the axial walls as nearly parallel as possible. Later investigations by J

Measurement of mandibular bone density ex vivo and in vivo by dual-energy X-ray absorptiometry

rgenserP suggested that the ideal angle was 5 to 10 degrees, and an angle greater than 10 degrees decreased retention by 50%. Other researchers2z7-9 recommended convergence angles between 10 and 16 degrees, on the basis of laboratory studies. More recently, Snoek and KSyser,‘O Eames et al.,” and Mack12 demonstrated that these laboratory figures are difficult to achieve under clinical conditions. Snoek and Kgyser” concluded that a convergence angle of 12 to 30 degrees was often used and that these angles were acceptable because they did not lead to failures. These findings agreed with those of Nordlander and Weir.‘) Mack12 believed the disparity between laboratory research and clinical application could be explained by the experience of the dentist.

Relation of axial bone mass to habitual calcium intake and to cortical bone loss in healthy early postmenopausal women.

Severe bone resorption is a vexing clinical problem, especially in patients without teeth. To study resorption in vivo, measurements of bone mineral density (BMD) of the mandible of both patients with and without teeth are needed. Using a Hologic QDR-1000 bone densitometer designed to measure lumbar spine and hips, ex vivo and in vivo measurements were made in selected areas of the mandible. The mandible was positioned such that the X-ray beam was perpendicular to its sagittal plane. In this way the beam hits first one half of the mandible and then the other. The reproducibility--expressed as coefficient of variation--of the ex vivo measurements was 0.5%. For in vivo measurements this coefficient was 3%. The method used for mandibular BMD would make it possible to define an average BMD in several categories of the normal population and of patients, and to compare bone density in the mandible with that in the axial and perpendicular skeleton. Improvement may be obtained by repeating the measurement. The entrance dose per scan is low, equalling that of one bitewing/radiograph.

Force-velocity relationship and contraction time of the rat fast plantaris muscle due to compensatory hypertrophy

A group of 60 healthy early postmenopausal women participating in an ongoing study on the effect of habitual calcium intake on the rate of cortical bone loss at the radius, were subjected to additional skeletal measurements at the lumbar spine and femoral neck. The women were between 58 and 64 years of age, and 3 to 10 years postmenopausal. No correlations were found between habitual calcium intake (range 560 to 2580 mg/day) and either bone mineral content of the radius, the lumbar spine and the femoral neck, or spine deformity index. Body mass index was found to be positively correlated with bone mass indices of the radius (decrease of BMD and BMD) and femoral neck (BMC), but not with of the lumbar spine (BMC, BMD and SDI), even after adjustments had been made for confounding factors. Although the rate of cortical bone loss at the radius correlated significantly with bone mineral content of lumbar spine and femoral neck, the error in predicting bone mass of the lumbar spine or the femoral neck from longitudinal measurements of cortical bone at the radius was high. The rate of cortical bone loss did not correlate with the spine deformity index. We conclude that in healthy women in early menopause, the bone mineral content of both the appendicular and the axial skeleton are not influenced by habitual calcium intake. A higher body mass index has a protective effect on the appendicular skeleton but appears to be less protective to the axial skeleton. Longitudinal measurements of cortical bone mass are of limited value to predict bone density of the appendicular and axial skeleton.