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Featured researches published by M. De Martino.


European Urology Supplements | 2015

200 Comparison of the prognostic value of pretreatment measurements of systemic inflammatory response in patients undergoing curative resection of clear cell renal cell carcinoma

Ilaria Lucca; M. De Martino; Sebastian L. Hofbauer; Nura Zamani; A. Briganti; S.F. Shariat; Tobias Klatte

Purpose Pretreatment measurements of systemic inflammatory response, including the Glasgow prognostic score (GPS), the neutrophil-to-lymphocyte ratio (NLR), the monocyte-to-lymphocyte ratio (MLR), the platelet-to-lymphocyte ratio (PLR) and the prognostic nutritional index (PNI) have been recognized as prognostic factors in clear cell renal cell carcinoma (CCRCC), but there is at present no study that compared these markers.


European Urology Supplements | 2010

C122 THE INSERTION/DELETION POLYMORPHISM OF THE ANGIOTENSIN I-CONVERTING ENZYME GENE IS LINKED WITH CHROMOPHOBE RENAL CELL CARCINOMA

Tobias Klatte; M. De Martino; Georg Schatzl; Mesut Remzi; Matthias Waldert; Peter Weibl; Andrea Haitel; Gero Kramer; M. Marberger

Objectives To study the putative significance of angiotensin I-converting enzyme (ACE) in renal cell carcinoma (RCC). Recent evidence has suggested that a 287-base pair insertion (I)/deletion (D) polymorphism (rs4646994) of the angiotensin I-converting enzyme (ACE) might be associated with cancer risk and progression. Methods The present case-control study accrued 383 subjects, including 210 with RCC and 173 age- and sex-matched healthy individuals without evidence or a history of cancer. Genomic DNA was extracted from the peripheral blood leukocytes. The ACE fragment containing the polymorphism was amplified using conventional polymerase chain reaction using specific primer pairs and subsequently genotyped using agarose gel electrophoresis. Results Overall, a DD genotype and D allele were more frequently noted in the patients with RCC than in the controls ( P = .042 and P = .045, respectively), and resulted from a greater frequency of DD and D in chromophobe RCC ( P = .023 and P = .020, respectively). In contrast, the genotype and allele distribution of the controls and patients with papillary or clear cell RCC was similar. The II genotype was not observed in any patient with chromophobe RCC. On multivariate logistic regression analysis, the ACE genotype was an independent risk factor for chromophobe RCC ( P = .012). Neither the ACE genotypes or alleles were associated with the tumor stage or grade. Conclusions The results of the present study have shown for the first time that the ACE insertion/deletion gene polymorphism rs4646994 might be linked with the development of chromophobe RCC. Neither the ACE genotypes nor the alleles were associated with RCC progression.


European Urology Supplements | 2015

647 The neutrophil-to-lymphocyte ratio as a prognostic factor for patients with urothelial carcinoma of the bladder following radical cystectomy: Validation and meta-analysis

Ilaria Lucca; S.F. Shariat; Morgan Rouprêt; Malte Rieken; Luis A. Kluth; Romain Mathieu; Harun Fajkovic; Alberto Briganti; Christian Seitz; Pierre I. Karakiewicz; M. De Martino; Yair Lotan; Marko Babjuk; Tobias Klatte


European Urology Supplements | 2008

PAPILLARY RENAL CELL CARCINOMA WITH CLEAR CELLS – PATHOLOGICAL, IMMUNOHISTOCHEMICAL AND CYTOGENETIC CHARACTERISTICS OF A NOVEL ENTITY

Tobias Klatte; Jonathan W. Said; David Seligson; M. De Martino; Jeffrey LaRochelle; Brian Shuch; Fairooz F. Kabbinavar; A.S. Belldegrun; A.J. Pantuck


European Urology Supplements | 2016

Development of a preoperative nomogram incorporating biomarkers of systemic inflammatory response to predict non-organ-confined urothelial carcinoma of the bladder at radical cystectomy

Tobias Klatte; Ilaria Lucca; Sebastian L. Hofbauer; Carmen V. Leitner; M. De Martino; Mehmet Özsoy; Harun Fajkovic; S.F. Shariat


European Urology Supplements | 2016

Perioperative allogenic blood transfusion in renal cell carcinoma: Risk factors and impact on long-term outcomes

Francesco Soria; M. De Martino; Carmen V. Leitner; Marco Moschini; S.F. Shariat; Tobias Klatte


European Urology Supplements | 2011

268 SERUM CELL-FREE DNA IN RENAL CELL CARCINOMA: A DIAGNOSTIC AND PROGNOSTIC MARKER

M. De Martino; Tobias Klatte; Andrea Haitel; M. Marberger


European Urology Supplements | 2011

274 THE SIX NUCLEOTIDE INSERTION/DELETION POLY-MORPHISM RS3834129 IN THE CASPASE8 PROMOTER IS ASSOCIATED WITH RISK AND PROGRESSION OF RENAL CELL CARCINOMA

M. De Martino; Tobias Klatte; Matthias Waldert; Mesut Remzi; Andrea Haitel; M. Marberger


European Urology Supplements | 2009

232 A NOMOGRAM PREDICTING DISEASE-SPECIFIC SURVIVAL AFTER NEPHRECTOMY FOR PAPILLARY RENAL CELL CARCINOMA

Tobias Klatte; Mesut Remzi; Jonathan W. Said; Andrea Haitel; Fairooz F. Kabbinavar; Matthias Waldert; M. De Martino; M. Marberger; A.S. Belldegrun; A.J. Pantuck


European Urology Supplements | 2009

239 FEATURES AND OUTCOMES OF RENAL CELL CARCINOMA IN RENAL TRANSPLANT RECIPIENTS: A 20-YEAR SINGLE CENTER EXPERIENCE

Tobias Klatte; Christian Seitz; Matthias Waldert; M. De Martino; M. Marberger; Mesut Remzi

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Tobias Klatte

University of California

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M. Marberger

Medical University of Vienna

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A.J. Pantuck

University of California

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Andrea Haitel

Medical University of Vienna

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Matthias Waldert

Medical University of Vienna

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