M. E. Perel'son

The structure of delavayine — An alkaloid from Stephania delovayi

ConclusionsThe definitive structure of delevayine — an alkaloid isolated earlier from the herbStephania delovayi — has been established.

Alkaloids of Stephania hernandifolia VIII. Methylhernandine

SummaryA new hasubanan alkaloid with the composition C20H27O6N, mp 152–153°C (ether-methanol) has been isolated from the herbStephania hernandifolia and has been called methylhernandine. The alkaloid has been shown to be identical with the methylamino alcohol obtained in the hydrolysis of hernandifoline.

Alkaloids of Stephania delavayi IV. Isostephodeline

SummaryThe structure of the new alkaloid isostephodeline isolated from the roots ofStephania delavayi Diels has been established. The most probable relative configurations of isostephodeline and of the stephodeline isolated previously have been proposed.

Alkaloids of Stephania delovayi III. Stephodeline

SummaryFrom the epigeal part ofStephania delovayi Diels (Menispermaceae) have been isolated cycleanine and a new amorphous alkaloid, stephodeline, with the composition C21H27O5N, a structure for which is proposed.

Alkaloids of Stephania delavayi II. 16-Oxodelavayine

The NMR spect rum of (I) is also very s imi lar to the spec t rum of delavayine. Below we give the cha r ac te r i s t ics of the NMR spec t rum of 16-oxodelavayine (HA-100D, CHC13; O TMS), showing its s t ructural similarity to delavayine [i]. Chemical shift, 5, ppm Assignment (multiplicity, * J=Hz) 6,64 (s) C4--H 6.46 (s) C,--H 5 88 (s) --O--CH2--O-4,10 (s) CHaO--C=C--C=O 3,66 (s) CHaO--C-C=O IJ C

Alkaloids of Stephania hernandifolia VI. Hernandifoline

SummaryA new hasubanan alkaloid with the composition C29H33O9N, mp 128–129°C9 from ether), [α]D20 – 25° (c 2; ethanol) containing an ester group has been isolated from the herbStephania hernandifolia and has been called hernandifoline.

Alkaloids ofHypecoum erectum, the structure of hyperectine

The structure of a new spirobenzylisoquinoline alkaloid fromHypecoum erectum L. has been established by spectral methods and also by the x-ray structural analysis of its methiodide. It has been shown that the alkaloid, which has been called hyperectine, has a pentacyclic structure in which the tetrahydroisoquinoline fragment has the sofa conformation and the indan fragment the envelope conformation. The natural alkaloid is a mixture of the enantiomeric C-8(S), C-16(R), and C-8(R), C-16(S) forms.

The structure of magnolamine

SummaryIt has been shown that the bisbenzylisoquinoline alkaloid magnolamine has the structure (II) and not the (I) proposed previously. The structure was determined on the basis of a study by the methods of NMR spectroscopy and mass spectrometry with the alkaloid and its transformation products.

Structure of nuphleine — An alkaloid from Nuphar luteum

SummaryA structure is proposed for nuphleine — a sulfur-containing alkaloid isolated previously from the roots of the European cowlily.