M. Joucla

Cycloadditions intramoleculaires cationique 3+ + 2 et dipolaire-1,3 de phenylhydrazones.

Resume In acidic medium, aikenyl phenylhydrazones lead, probably via a 3 + +2 cationic cycloaddition, to fused ring systems, which are difficult to obtain as primary products of thermal 1,3 dipolar cycloaddition.

Pyrrolidines from α-amino-acids derivatives

On heating with benzaldehyde and alkenes, N-alkylamino acids derivatives lead to pyrrolidines.

Flash vacuum thermolysis of oxazolidines: A new way to reactive azomethine ylides. Regio and stereospecific synthesis of substituted pyrrolidines.

Abstract Flash vacuum thermolysis of oxazolidines leads to azomethine ylides trapped by an intramolecular 1,3-dipolar cycloaddition reaction which occured only in the gas phase.

Réactivité des imines vis-à-vis d'alcènes gem disubstitués. synthèse d'aza-1 bicyclo (2,1,0) pentanes

Abstract Imines undergo 1,3 dipolar cycloadditions reactions as well as 3- +2 polar cycloadditions reactions with alkenes substituted at the same carbon atom with an electron withdrawing group and a leaving group to give heterocyclic compounds.

Flash vacuum thermolysis of oxazolioines: a new way to reactive azomethine ylides. Ring closure to aziridines.

Abstract Flash vacuum thermolysis of oxazolidines leads to azomethine ylides which undergo ring closure to aziridines.

Reactions de cyclisations induites par des fluorures alcalins : Formation de cyclopropanes.

Resume Fluorides acted as bases in cyclopropane ring formation from nucleophiles and Michael acceptors. With cyano alkenes, Si(OR) 4 improved the yields of the reaction.

Réactions de cyclopropanation par double addition de Michael.

Abstract The addition of nucleophiles to alkyl α bromoacrylates in aprotic media leads to the stereospecific formation of cyclopropanes by a double Michael addition reaction.

2,5-Unsubstituted pyrrolidines from formaldehyde and amino acids through in situ azomethine-ylide 1,3-dipolar cycloaddition to alkenes

Formaldehyde and α-amino acids such as sarcosine and glycine react with alkenes to give N-Me and N-H Pyrrolidines via in situ generated azomethine-yields.