M. Mushfiq

Flavonoids from Acacia tortilis

A novel isoflavone, 5,7-dihydroxy-4′- p-methyl benzyl isoflavone 1a, and three known flavonoids apigenin, luteolin and quercetin have been isolated from the leaves of Acacia tortilis. Their structures were elucidated by chemical and physical data (IR, UV, 1H-NMR, 13C-NMR and MS spectra).

A new Biflavonoid from Leaves of Garcinia Nervosa

The isolation of a new biflavonoid, identified as I-3, II-3, I-5, II-5, I-7, II-7, I-4′, II-4′-octahydroxy [I-2′, II-2′] biflavone, from the leaves of Garcinia nervosa is reported. The structure was established by chemical and physical means (IR, UV, 1H-NMR, 13C-NMR data).

A new benzofuranic acid from the leaves of Rhus alata.

From leaves of Rhus alata, one new benzofuranic acid named [(2E)-3-(4-hydroxy-5,7-dimethyl- benzo[3,4-b] furan-6-yloxy)-prop-2-enoic acid has been isolated together with eight known compounds: dimethyl ester of terephthalic acid, β-amyrin, friedelin, lupeol, β-sitosterol, oleanolic acid, taraxerone and ethyl gallate. Structural elucidations were done on the basis of chemical and physical data (IR, UV, 1H-NMR, 13C-NMR and MS spectra).

Synthesis of Steroidal Oxazolidine Thiones in the Cholestane Series

Abstract Steroidal α‐epoxides (I, III, and VIII) on reaction with 4‐fluorophenylisothiocyanate give the corresponding oxazolidine thiones (II, V, VI, VII, and XI) along with other products (IV and IX). Characterization of the compounds is based on spectral properties and elemental analysis.

Flavonoid from Viburnum cotinifolium

From the leaves of Viburnum cotinifolium, a new biflavonoid named as I-5, II-5, I-7, II-7, I-4’, II-4′-hexahydroxy [6-O-8] biflavone along with seven known flavonoids have been isolated. Their structures were elucidated from their chemical and physical data (IR, UV, 1H NMR, 13C NMR and mass spectra).

Synthesis of Acylated Steroidal Olefins and Their Derivatives

Acylation of cholest-5-ene and cholest-5-ene 3-one with anhydrides in the presence of zinc chloride and characterization of products thus obtained on the basis of elemental analysis, spectral data, and chemical transformations are reported.

Synthesis of Some New Arylmethylidene Steroidal Compounds

An efficient method for the formation of new arylmethylidene steroidal compounds by the reaction of ketones with 4-(N,N-dimethylamino)benzaldehyde is described.