M. Odeh

Placental volume and three‐dimensional power Doppler analysis in prediction of pre‐eclampsia and small for gestational age between Week 11 and 13 weeks and 6 days of gestation

To assess three‐dimensional placental volume measurement and three‐dimensional power Doppler (3D‐PD) indices between 10 weeks and 6 days and 13 weeks and 6 days in predicting pregnancy‐induced hypertension (PIH) and small for gestational age (SGA).

Monochorionic diamniotic in vitro fertilization twins have a decreased incidence of twin-to-twin transfusion syndrome

OBJECTIVE To compare the incidence of twin-to-twin transfusion syndrome (TTTS) in spontaneous versus IVF-conceived twin pregnancies. DESIGN Retrospective multicenter study. SETTING University-affiliated tertiary medical centers. PATIENT(S) Women admitted for 11-14 weeks scan between January 1997 and July 2013 who were diagnosed with monochorionic (MC) diamniotic twin pregnancies. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Mode of conception, TTTS. RESULT(S) The study cohort included 327 pregnant women with live MC diamniotic twins. Of them, 284 (86.9%) and 43 (13.1%) were spontaneous and IVF conceived, respectively. The mean maternal age was significantly higher in IVF compared with in spontaneously conceived pregnancies (33.8 ± 5.5 vs. 31.6 ± 5.4, respectively). Thirty-seven twins (11.3%) had TTTS, of whom 36/284 (12.7%) versus 1/43 (2.3%) were spontaneously and IVF conceived, respectively. The mean week of delivery was significantly lower in MC twins diagnosed with TTTS compared with those without TTTS (32.7 ± 3.3 vs. 35.5 ± 2.5, respectively). Furthermore, there was a significantly higher birthweight discordancy in twins diagnosed with TTTS compared with those without (20.6% vs. 11%, respectively). CONCLUSION(S) The significantly lower proportion of TTTS found in IVF-conceived twins may suggest a different embryological process that lies at the core of IVF conception of monozygotic twinning.

Gestational sac volume in missed abortion and anembryonic pregnancy compared to normal pregnancy

To compare gestational sac (GS) volume (GSV) between normal pregnancies and missed abortions and anembryonic pregnancies and to determine at what gestational age differences in GS volume become evident.

Fetal eyeball volume: relationship to gestational age and biparietal diameter.

To measure and determine normal values of the fetal eyeball volume between 14 and 40 weeks of gestation.

The association of crown–rump length discrepancy with birthweight discordance in spontaneous versus assisted conception dichorionic twins

This study aimed to compare the associations of crown–rump length (CRL) discrepancy with birthweight discordance in spontaneous versus vitro fertilization (IVF) conceived dichorionic twin pregnancies.

Normal fetal salivary glands at 14-16 weeks of gestation as observed by transvaginal ultrasound imaging

Absence or congenital anomalies of the parotid glands are associated with significant long‐term morbidity. To date there are no published data on ultrasonographic detection of these defects in early pregnancy. We set out to demonstrate and measure the fetal parotid and submandibular salivary glands at 14–16 weeks using transvaginal ultrasound imaging.

P23.04: The value of 3D Doppler indices in prediction of successful medical treatment in missed abortion

Results: There was no significant difference between groups in age (t=-1,7; p>0,05), in previous gravida numbers (U=3577,5; p>0,1), pelvic inflammatory diseases rate (χ2 =1,31; p>0,05), adnexa surgery numbers (U=3220,5; p>0,1), spotting days (t=-1,7; p=0,088). Significant difference was revealed in the uterus surgery numbers (U=1214,5; p<0,001), parity (U=2746,5; p<0,05), Caesarean scar numbers (U=2170; p<0,001). In 2nd group the gestation age, HCG-level, the presence of embryo cardiac activity, ultrasound mistakes rate and time from first admission for right diagnosis were significantly higher (U=1245; p<0,001, U=646,5; p<0,001, χ2 =16,6 p<0,0001, χ2 =20,2, p<0,05, U=1886; p<0,001 respectively). Intraoperative blood loss, operation time, follow-up duration, chorion persistence rate, readmission rate in LIP were significantly higher than in tubal pregnancy (U=2692,5; p<0,05, χ2 =28,0; p<0,0001, U=1284; p<0,0001, U=257,5; p<0,0001, χ2 =22,0; p<0,0001, χ2 =29,9; p<0,0001 respectively). Conclusions: Early ultrasound criteria are necessary for correct diagnosis of LIP among patients with previous surgery on uterus.

OP12.01: Early pregnancy failure: Factors affecting successful medical termination

Methods: In this cross – sectional study, we prospectively enrolled hypertensive (Group1) and normal pregnancies (Group2) during antenatal, immediate postpartum or late postpartum period. Group1 included women with gestational hypertension, preeclampsia, eclampsia, chronic hypertension or superimposed preeclampsia. By transvaginal approach, bilateral uterine artery indices were measured and then mean values of bilateral indices were calculated. Nonparametric techniques were used for statistical analysis. Results: A total of 94 women were enrolled. In antenatal period, UA – PI of hypertensive pregnancies was higher than that of normal pregnancies. UA – PI of Group1 in immediate postpartum period was also higher than that of Group2, reaching statistical significance. Although it was not statistically significant, UA – PI of Group1 showed higher tendency than that of Group2 in late postpartum period.

OP03.09: Fetal orbits volume: Relationship to gestational age and the biparietal diameter and the femur length

MILD 66 54% 29 44% 7 11% 30 45% isolated 26 21% 3 5% 1 2% 22 33% marker 5 4% 0 0% 0 0% 5 8% CNS: NTD 21 17% 19 29% 1 2% 1 2% CNS: cranial anomalies 3 2% 2 3% 1 2% 0 0% other anomalies 6 5% 3 5% 1 2% 2 3% CNS and other 5 4% 2 3% 3 5% 0 0% MODERATE 25 20% 17 68% 2 8% 6 24% isolated 5 4% 3 12% 0 0% 2 8% marker 1 1% 0 0% 0 0% 1 4% CNS: NTD 13 11% 10 40% 0 0% 3 12% CNS: cranial anomalies 0 0% 0 0% 0 0% 0 0% other anomalies 5 4% 4 16% 1 4% 0 0% CNS and other 1 1% 0 0% 1 4% 0 0% SEVERE 31 25% 27 87% 0 0% 4 13% isolated 8 7% 6 19% 0 0% 3 10% marker 3 2% 3 10% 0 0% 0 0% CNS: NTD 6 5% 5 16% 0 0% 1 3% CNS: cranial anomalies 6 5% 5 16% 0 0% 0 0% other anomalies 6 5% 6 19% 0 0% 0 0% CNS and other 2 2% 2 6% 0 0% 0 0% TOTAL 122 100% 73 60% 9 7% 40 33%

P33.14: Hypospadias mimicking female genitalia on early second trimester sonographic examination : Report of three cases

Doppler we demonstrated flow in the dilation and with pulsed Doppler we found that the flow was arterial. With these findings our diagnosis was aneurysm of the umbilical artery. The rest of the fetal exploration and measurements were normal. The diameter of the aneurysm increased throughout the pregnancy. In view of fetal risk, delivery was performed at 34 weeks. The post-delivery examination of the umbilical cord confirmed the diagnosis. After six months, the baby is doing well. Discussion: The aneurysm was seen early at 19 weeks and coexisted with other alterations of the umbilical cord. The diameter increased with gestational age. In a previously reported case, there was intrauterine fetal death at 36 gestational weeks and it was speculated that the stretching and compressing of an uninvolved vein over the expanding aneurysm was the cause of the fetal asphyxia. For this reason and because of the increased diameter of the aneurysm we decided to deliver the baby at 34 weeks. Conclusion: If umbilical cord aneurysm is diagnosed, we must consider pre-term delivery of the fetus to prevent fetal damage and/or death.