M. Pelletier

557 Long-Term Results Following Mitral Valve Repair Surgery Performed at a Small-Volume Cardiac Surgery Center Between 1991 and 2008

status postoperatively (odds ratio 2.6 1.3 per increasing MR grade; P 0.07). CONCLUSION: After mitral valve repair for ischemic MR, persistent or recurrent MR of mild to moderate degree appears associated with functional compromise. This finding carries implications with regards to the ongoing controversy of repair versus replacement for ischemic MR, and for new percutaneous mitral therapies which may not eradicate MR.

190Factor VIII inhibitor bypassing activity (FEIBA) as an adjunct in post-cardiotomy bleeding

adverse events was determined using multivariable regression modeling. A total of 2747 patients were considered (weekday: n 1884; weekend: n 863). Patients discharged home on weekends were less likely to have been 70yrs (29.3% vs. 33.2%, P 0.04) and to have had pre-operative atrial fibrillation (4.0% vs. 6.4%, P 0.01). Post-operatively, they were less likely to have had atrial fibrillation (23.3% vs. 35.2%, P 0.0001) and renal failure (4.2% vs. 7.0%, P 0.005) and to have been discharged home on the provincial homecare program (7.9% vs. 11.7%, P 0.003). They also experienced a shorter post-operative length of stay (4.9 days vs. 5.4 days, P 0.0001). Overall rates of 30-day adverse events did not differ between the two groups (28.2% vs. 31.1%, P 0.12). Following adjustment for differences between the two groups, weekend discharge did not emerge as a significant predictor of worse short-term outcomes following cardiac surgery (OR 0.94, 95% CI 0.78-1.13). CONCLUSION: Weekend discharge following cardiac surgery is safe. However, patients with post-operative atrial fibrillation, renal failure and need for homecare were less likely to be discharged home on weekends. This may highlight the reduced availability of resources on weekends which, in turn, may have prolonged hospital length of stay in these patients and, ultimately, increased cost to the health care system.