M. Prabhuswamy

Synthesis, Crystal Structure, and Characterization of New 2,4,5-Triphenyl Imidazole: 4,5-Diphenyl-2-(3,4,5-trimethoxyphenyl)-1H-imidazole

The substituted triarylimidazole, C24H22N2O3, was prepared from the three-component one-pot condensation reaction and the product was crystallized by using dimethylformamide. The structure of the compound was confirmed by elemental analysis, FT-IR, thermogravimetric analysis (TGA), UV-Visible and single-crystal X-ray diffraction. The compound crystallizes in the monoclinic crystal system in the space group P21/c with unit cell parameters a = 10.509(3) Å, b = 18.748(5) Å, c = 22.016(6) Å, β = 90.844(5)°, and Z = 8. The crystal structure of the compound was stabilized by the inter-molecular interactions of types N–H⋅⋅⋅N, C–H⋅⋅⋅O, and C–H⋅⋅⋅N, and intra-molecular interactions of the type C–H⋅⋅⋅O. The structure also involves C–H⋅⋅⋅π interactions.

Synthesis Characterization and Crystal Structure of 2-(3,4,5-trimethoxyphenyl)-1-(4-fluorophenyl)-4,5-diphenyl-1H-imidazole

The title compound, C30H25FN2O3, was prepared from the four-component one-pot condensation reaction and the product crystallized using dimethylformamide. The structure of the compound was established by elemental analysis, Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), UV-Visible, and single-crystal X-ray diffraction. The compound crystallizes in the triclinic crystal system with the space group Pī, with unit cell parameters a = 10.286(2) Å, b = 11.795(2) Å, c = 21.331(4) Å, α = 100.270(3)°, β = 90.093(3)°, γ = 90.062(3)°, and Z = 4. The crystal and molecular structure of the title molecule is stabilized by intra-molecular interactions of types C–H···N and C–H···O.

2-(4-Chloro­phen­yl)-6-methyl-4-(3-methyl­phen­yl)quinoline

In the title compound, C23H18ClN, the dihedral angles between the quinoline unit and the chlorobenzene and methylbenzene rings are 2.57 (9) and 56.06 (9)°, respectively. The crystal structure is stabilized by π–π interactions [minimum ring centroid separation = 3.733 (2) Å].

Synthesis, Characterization, Crystal Structure, and Hirshfeld Surface Analysis of 2–(2–Hydroxy–3–methoxyphenyl)–1–(4–methylphenyl)–4, 5–diphenyl–1H–imidazole

The substituted imidazole C29H24N2O2 was prepared via multicomponent reactions and the product crystallized using dimethylformamide. The structure of the compound was established by elemental analysis, FT-IR, thermogravimetric analysis, UV-Visible, and single-crystal X-ray diffraction. The molecule is crystallized in the tetragonal crystal system with the space group P43212 and with unit cell parameters a = 12.226(1) Å, b = 12.226(1) Å, c = 31.807(3) Å, and Z = 8. The molecular and crystal structure of the title molecule is stabilized by intramolecular interactions, O‒H···N and C‒H···N, and intermolecular interaction, C‒H···O.

Synthesis, Crystal Structure and Characterization of (Z)-2-N′-hydroxyisonicotinamidine

The compound (Z)-2-N′-hydroxyisonicotinamidine, (2) was synthesized and characterized by 1H NMR, FT-IR, FAB-Mass, UV-Visible Spectra, and elemental Analysis. Its molecular structure was solved by single crystal X-ray diffraction method. The title molecule, C6H7N3O is crystallized in the orthorhombic crystal system with the space group Pna21 and with unit cell parameters a = 12.5664(8) Å, b = 8.8622(6) Å, c = 5.7953(4) Å, α = 90°, β = 90°, γ = 90°, and Z = 4. The molecular and crystal structure of the title molecule is stabilized by an intramolecular interaction of the type N—H···O, and the intermolecular interactions of types N—H···N and O—H···N.

4-[Amino­(3-methyl­phen­yl)methyl­idene]-2-(3-methyl­phen­yl)-1H-imidazol-5(4H)-one ethanol hemisolvate

In the title compound, C18H17N3O·0.5C2H5OH, the dihedral angles between the central imidazole rings and the pendant benzene rings are 42.06 (15) and 2.01 (16)° in one asymmetric molecule and 47.91 (15) and 7.31 (14)° in the other. An intramolecular N—H⋯O hydrogen bond occurs in each imidazole molecule. In the crystal, the components are connected by O—H⋯N, N—H⋯O, C—H⋯O and N—H⋯N hydrogen bonds. Weak aromatic π–π interactions also occur [shortest centroid–centroid distance = 3.684 (3) Å].

Synthesis, characterization, and crystal structure analysis of 2-(2-hydroxy-3-methoxyphenyl)-1-(4-chlorophenyl)-4,5-diphenyl-1h-imidazole

ABSTRACT The substituted imidazole C28H21ClN2O2, was prepared via multicomponent reactions and the product crystallized using dimethylformamide. The structure of the compound was established by elemental analysis, Fourier transform infrared spectroscopy, thermogravimetric analysis, UV-visible, proton nuclear magnetic resonance spectroscopy, and single-crystal X-ray diffraction. The molecule is crystallized in the tetragonal crystal system with the space group P43212 and with unit cell parameters a = 12.246(4) Å, b = 12.246(4) Å, c = 31.781(2) Å, and Z = 8. The molecular and crystal structures of the title molecule are stabilized by the intramolecular interactions, O-H···N and C-H···N, and intermolecular interaction, C-H···O.

Synthesis, Crystal Structure, and Characterization of (Z)-2-(3-chlorophenyl)-N’-hydroxyacetamidine

The compound (Z)-2-(3-chlorophenyl)-N’-hydroxyacetamidine, (2) was synthesized and characterized by 1H NMR, FT-IR, TGA, UV-Visible Spectra, and elemental analysis. Its molecular structure was solved by single-crystal X-ray diffraction method. The title molecule, C8H9ClN2O is crystallized in the monoclinic crystal system with the space group P21/c and with unit cell parameters a = 8.7092(4) Å, b = 8.2370(4) Å, c = 12.5256(6) Å, β = 102.252(3)°, and Z = 4. The molecular and crystal structure of the title molecule is stabilized by an intramolecular interaction of the type N—HċċċO, and the intermolecular interactions of types N—HċċċN and O—HċċċN.

Synthesis, Characterization, and Crystal Structure of (E)-1-(4-(1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamino)phenyl)-3-phenylprop-2-en-1-one

(E)-1-(4-(1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamino)phenyl)-3-phenylprop-2-en-1-one, C29H26N4O, was synthesized and characterized by spectroscopy and elemental analysis. The crystal structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic crystal system with the space group Pī, and unit cell parameters, a = 9.667(2) Å, b = 11.408(3) Å, c = 12.286(3) Å, α = 116.7(1)°, β = 91.5(1)°, γ = 99.6(1)°, Z = 2, CuKα = 1.5418 Å, and final R1 and wR2 being 0.067 and 0.189, respectively. The molecular and crystal structures of the title molecule are stabilized by intramolecular interactions, N—H···N, C—H···N, and C—H···O, and intermolecular interaction, C—H···O.

6,7-Dimeth-oxy-2,4-di-phenyl-quinoline.

In the title structure of the title compound, C23H19NO2, two conformationally similar molecules (A and B) comprise the asymmetric unit. The dihedral angle between phenyl rings bridged by the quinoline moiety are 76.25 (8)° in molecule A and 70.39 (9)° in molecule B. In the crystal, the independent molecules are connected by C—H⋯O hydrogen bonds and the resulting dimeric aggregates are linked by π–π [inter-centroid distance = 3.7370 (8) Å] and C—H⋯π interactions, forming a three-dimensional architecture.